Multi-color Flow Cytometric Analysis of Samples with Low Cell Numbers

    公开(公告)号:US20200225143A1

    公开(公告)日:2020-07-16

    申请号:US16837900

    申请日:2020-04-01

    IPC分类号: G01N15/14

    摘要: Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include contacting a biological sample having cells with an assay reagent that includes one or more analyte-specific binding members to produce a biological sample assay composition and introducing the biological assay composition into an inlet of a flow cytometer having an integrated acoustic separator. Systems, including a flow cytometer with integrated acoustic separator having one or more acoustic concentrator devices suitable for practicing the subject methods are also described.

    DEVICES AND METHODS FOR DISSOCIATING A BIOLOGICAL TISSUE SAMPLE
    3.
    发明申请
    DEVICES AND METHODS FOR DISSOCIATING A BIOLOGICAL TISSUE SAMPLE 审中-公开
    用于分解生物组织样品的装置和方法

    公开(公告)号:US20160069781A1

    公开(公告)日:2016-03-10

    申请号:US14817789

    申请日:2015-08-04

    IPC分类号: G01N1/28

    摘要: Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators may include a housing having a distal end and a proximal end, a cutting blade positioned at the distal end of the housing and a tissue actuator configured to be displaced along a longitudinal axis within the housing. Also provided are methods of using the tissue dissociators, as well as kits including the tissue dissociators.

    摘要翻译: 提供了构造成破坏生物组织样品的组织解离器。 组织解离器的方面可以包括具有远端和近端的壳体,设置在壳体的远端处的切割刀片和构造成沿壳体内的纵向轴线移位的组织致动器。 还提供了使用组织解离器的方法,以及包括组织解离器的试剂盒。

    Multi-color flow cytometric analysis of samples with low cell numbers

    公开(公告)号:US10648900B2

    公开(公告)日:2020-05-12

    申请号:US15371088

    申请日:2016-12-06

    IPC分类号: G01N15/14 G01N15/10 G01N15/00

    摘要: Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include contacting a biological sample having cells with an assay reagent that includes one or more analyte-specific binding members to produce a biological sample assay composition and introducing the biological assay composition into an inlet of a flow cytometer having an integrated acoustic separator. Systems, including a flow cytometer with integrated acoustic separator having one or more acoustic concentrator devices suitable for practicing the subject methods are also described.