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1.发明申请Ophthalmic devices comprising photochromic materials having extended PI-conjugated systems 审中-公开眼科装置包括具有延长的PI共轭系统的光致变色材料公开(公告)号：US20060226402A1
公开(公告)日：2006-10-12
申请号：US11102047
申请日：2005-04-08
申请人： Beon-Kyu Kim , Jun Deng , Wenjing Xiao , Barry Van Gemert , Anu Chopra , Frank Molock , Shivkumar Mahadevan
发明人： Beon-Kyu Kim , Jun Deng , Wenjing Xiao , Barry Van Gemert , Anu Chopra , Frank Molock , Shivkumar Mahadevan
CPC分类号： C09K9/02 , C09B57/02 , C09B69/109 , C09K2211/1007 , C09K2211/1011 , C09K2211/1059 , C09K2211/1088 , C09K2211/1096 , G02B1/043 , C08L101/14
摘要： Various non-limiting embodiments disclosed herein relate to ophthalmic devices comprising photochromic materials having extended pi-conjugated systems. For example, various non-limiting embodiments disclosed herein provide a photochromic material, such as an indeno-fused naphthopyran, which comprises a group that extends the pi-conjugated system of the indeno-fused naphthopyran bonded at the 11-position of thereof. Further, the photochromic materials according to certain non-limiting embodiments disclosed herein may display hyperchromic absorption of electromagnetic radiation as compared to conventional photochromic materials and/or may have a closed-form absorption spectrum that is bathochromically shifted as compared to conventional photochromic materials. Other non-limiting embodiments relate to methods of making the ophthalmic devices comprising photochromic materials.
摘要翻译： 本文公开的各种非限制性实施方案涉及包含具有延伸的π-共轭体系的光致变色材料的眼科装置。 例如，本文公开的各种非限制性实施方案提供光致变色材料，例如茚并稠合的萘并吡喃，其包含延伸在其11位键合的茚并稠合的萘并吡喃的π-共轭体系的基团。 此外，与常规光致变色材料相比，根据本文公开的某些非限制性实施方案的光致变色材料可以显示电磁辐射的超色吸收和/或可以具有与常规光致变色材料相比被红移的闭合形式的吸收光谱。 其它非限制性实施方案涉及制备包含光致变色材料的眼科装置的方法。
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2.发明申请OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS 审中-公开包含具有扩展PI连接系统的光致变色材料的光学器件公开(公告)号：US20090072206A1
公开(公告)日：2009-03-19
申请号：US12265842
申请日：2008-11-06
申请人： Beon-Kyu Kim , Jun Deng , Wenjing Xiao , Barry Van Gemert , Anu Chopra , Frank Molock , Shivkumar Mahadevan
发明人： Beon-Kyu Kim , Jun Deng , Wenjing Xiao , Barry Van Gemert , Anu Chopra , Frank Molock , Shivkumar Mahadevan
IPC分类号： G02B5/23
CPC分类号： C09K9/02 , C09B57/02 , C09B69/109 , C09K2211/1007 , C09K2211/1011 , C09K2211/1059 , C09K2211/1088 , C09K2211/1096 , G02B1/043 , C08L101/14
摘要： Various non-limiting embodiments disclosed herein relate to ophthalmic devices comprising photochromic materials having extended pi-conjugated systems. For example, various non-limiting embodiments disclosed herein provide a photochromic material, such as an indeno-fused naphthopyran, which comprises a group that extends the pi-conjugated system of the indeno-fused naphthopyran bonded at the 11-position of thereof. Further, the photochromic materials according to certain non-limiting embodiments disclosed herein may display hyperchromic absorption of electromagnetic radiation as compared to conventional photochromic materials and/or may have a closed-form absorption spectrum that is bathochromically shifted as compared to conventional photochromic materials. Other non-limiting embodiments relate to methods of making the ophthalmic devices comprising photochromic materials.
摘要翻译： 本文公开的各种非限制性实施方案涉及包含具有延伸的π-共轭体系的光致变色材料的眼科装置。 例如，本文公开的各种非限制性实施方案提供光致变色材料，例如茚并稠合的萘并吡喃，其包含延伸在其11位键合的茚并稠合的萘并吡喃的π-共轭体系的基团。 此外，与常规光致变色材料相比，根据本文公开的某些非限制性实施方案的光致变色材料可以显示电磁辐射的超色吸收和/或可以具有与常规光致变色材料相比被红移的闭合形式的吸收光谱。 其它非限制性实施方案涉及制备包含光致变色材料的眼科装置的方法。
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3.发明授权Ophthalmic devices comprising photochromic materials with reactive substituents 有权包含具有反应性取代基的光致变色材料的眼科装置公开(公告)号：US09052438B2
公开(公告)日：2015-06-09
申请号：US11101979
申请日：2005-04-08
摘要： Various non-limiting embodiments of the present disclosure relate to ophthalmic devices comprising photochromic materials comprising a reactive substituent. For example, the present disclosure contemplates ophthalmic devices comprising photochromic materials, such as photochromic naphthopyrans and indeno-fused naphthopyrans having a reactive substituent comprising a reactive moiety linked to the photochromic naphthopyran by one or more linking groups. In certain non-limiting embodiments, the reactive moiety comprises a polymerizable moiety. In other non-limiting embodiments, the reactive moiety comprises a nucleophilic moiety. Other non-limiting embodiments of the present disclosure relate to methods of making the photochromic ophthalmic device, wherein the photochromic ophthalmic devices comprise the photochromic naphthopyrans described herein.
摘要翻译： 本公开的各种非限制性实施方案涉及包含含有反应性取代基的光致变色材料的眼科装置。 例如，本公开涉及包含光致变色材料的光学装置，例如具有包含通过一个或多个连接基团与光致变色萘并吡喃连接的反应性部分的反应性取代基的光致变色萘并吡喃和茚并稠合萘并吡喃。 在某些非限制性实施方案中，反应性部分包含可聚合部分。 在其它非限制性实施方案中，反应性部分包含亲核部分。 本公开的其它非限制性实施方案涉及制备光致变色眼科装置的方法，其中光致变色眼科装置包含本文所述的光致变色萘并吡喃。
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公开(公告)号：US20060226401A1
公开(公告)日：2006-10-12
申请号：US11101979
申请日：2005-04-08
摘要： Various non-limiting embodiments of the present disclosure relate to ophthalmic devices comprising photochromic materials comprising a reactive substituent. For example, the present disclosure contemplates ophthalmic devices comprising photochromic materials, such as photochromic naphthopyrans and indeno-fused naphthopyrans having a reactive substituent comprising a reactive moiety linked to the photochromic naphthopyran by one or more linking groups. In certain non-limiting embodiments, the reactive moiety comprises a polymerizable moiety. In other non-limiting embodiments, the reactive moiety comprises a nucleophilic moiety. Other non-limiting embodiments of the present disclosure relate to methods of making the photochromic ophthalmic device, wherein the photochromic ophthalmic devices comprise the photochromic naphthopyrans described herein.
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公开(公告)号：US20060227287A1
公开(公告)日：2006-10-12
申请号：US11102319
申请日：2005-04-08
IPC分类号： G02C7/10
摘要： The present invention relates to a process comprising exposing a polymerizable mixture comprising at least one lens forming component, at least one thermal initiator, at least one photoinitiator and at least one photochromic compound to device forming conditions comprising heat and actinic radiation to form a photochromic ophthalmic device.
摘要翻译： 本发明涉及包括将包含至少一种透镜形成组分，至少一种热引发剂，至少一种光引发剂和至少一种光致变色化合物的可聚合混合物暴露于包含热和光化辐射的装置形成条件，以形成光致变色眼科 设备。
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公开(公告)号：US20050197505A1
公开(公告)日：2005-09-08
申请号：US11123430
申请日：2005-05-06
CPC分类号： C07F7/0889 , C07C67/26 , C07C69/54
摘要： The present invention relates to a process comprising the steps of reacting in the presence of an epoxide opening catalyst, a substituted epoxide, and preferably a silicone containing substituted epoxide with at least one carboxylic acid and at least one protecting agent to form a vicinal dialkyl ester or a vicinal disilyl ester.
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公开(公告)号：US06933401B2
公开(公告)日：2005-08-23
申请号：US10610262
申请日：2003-06-30
CPC分类号： C07F7/0889 , C07C67/26 , C07C69/54
摘要： The present invention relates to a process comprising the steps of reacting in the presence of an epoxide opening catalyst, a substituted epoxide, and preferably a silicone containing substituted epoxide with at least one carboxylic acid and at least one protecting agent to form a vicinal dialkyl ester or a vicinal disilyl ester.
摘要翻译： 本发明涉及一种方法，该方法包括以下步骤：在环氧化物开环催化剂，取代的环氧化物，优选含有硅氧烷的取代的环氧化物存在下，与至少一种羧酸和至少一种保护剂反应形成连位二烷基酯 或邻位二甲硅烷基酯。
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公开(公告)号：US09297928B2
公开(公告)日：2016-03-29
申请号：US10994717
申请日：2004-11-22
IPC分类号： A61K31/785 , A61K31/74 , A61F2/00 , G02B1/04
CPC分类号： A61K9/0048 , A61K31/765 , A61K31/78 , C11D3/0078 , G02B1/041 , G02B1/043 , C08L33/12
摘要： The present invention relates to ophthalmic solutions and devices comprising at least one water soluble polymer having a molecular weight of at least about 500,000 Daltons and linear or branched polyether pendant groups having a molecular weight of at least about 300.
摘要翻译： 本发明涉及眼用溶液和装置，其包含至少一种分子量至少为约500,000道尔顿的水溶性聚合物和分子量至少为约300的直链或支链聚醚侧基。
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公开(公告)号：US08466174B2
公开(公告)日：2013-06-18
申请号：US11686988
申请日：2007-03-16
IPC分类号： A01N43/40 , A61K31/445
CPC分类号： A61K31/4535 , A61K9/0048 , A61K9/08 , A61K47/18 , A61K47/183 , A61K47/32
摘要： Ophthalmic compositions and methods of preparing such compositions are disclosed.
摘要翻译： 公开了制备这种组合物的眼用组合物和方法。
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公开(公告)号：US08222353B2
公开(公告)日：2012-07-17
申请号：US13206702
申请日：2011-08-10
申请人： Osman Rathore , Shivkumar Mahadevan , Frank Molock , Azaam Alli , David Turner , Douglas G. Vanderlaan , Kevin P. McCabe
发明人： Osman Rathore , Shivkumar Mahadevan , Frank Molock , Azaam Alli , David Turner , Douglas G. Vanderlaan , Kevin P. McCabe
IPC分类号： C08F290/06
CPC分类号： C08L101/14 , C08G77/14 , C08G77/20 , C08G77/24 , C08G77/26 , C08G77/38 , C08G77/42 , C08G77/70 , C08G81/024 , C08L83/04 , G02B1/043 , C08L2666/20
摘要： The present invention relates to biomedical devices, and particularly contact lenses comprising a polymer having entangled therein at least one acyclic polyamide.
摘要翻译： 本发明涉及生物医学装置，特别涉及包含其中缠绕有至少一种无环聚酰胺的聚合物的隐形眼镜。
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