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公开(公告)号：US08729123B2
公开(公告)日：2014-05-20
申请号：US13251399
申请日：2011-10-03
CPC分类号： A61K31/202 , A23L33/12 , A23L33/22 , A23L33/40 , A23V2002/00 , A23V2250/187 , A23V2250/1868 , A23V2250/5046 , A23V2250/1872 , A23V2250/1874 , A23V2250/0644 , A23V2250/1642
摘要： The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt % docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.
摘要翻译： 本发明涉及长链多不饱和脂肪酸用于制造用于喂养怀孕期间代谢紊乱的母亲的婴儿的营养组合物和相应组合物的用途。 所述组合物包含n-3多不饱和脂肪酸级分，其含有基于脂质总重量的至少0.1重量％二十二碳六烯酸（DHA），至少0.01重量％的n-3二十二碳五烯酸（DPAn-3），基于 脂质和至少0.01重量％ 基于脂质总重量的二十碳五烯酸（EPA），其中DHA，DPAn-3和EPA的总和低于1wt。 总脂质的百分比。
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公开(公告)号：US20080269330A1
公开(公告)日：2008-10-30
申请号：US11666990
申请日：2005-11-11
IPC分类号： A61K31/202 , A61P3/02
CPC分类号： A61K31/202 , A23L33/12 , A23L33/22 , A23L33/40 , A23V2002/00 , A23V2250/187 , A23V2250/1868 , A23V2250/5046 , A23V2250/1872 , A23V2250/1874 , A23V2250/0644 , A23V2250/1642
摘要： The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.
摘要翻译： 本发明涉及长链多不饱和脂肪酸用于制造用于喂养怀孕期间代谢紊乱的母亲的婴儿的营养组合物和相应组合物的用途。 所述组合物包含n-3多不饱和脂肪酸级分，其含有至少0.1重量％的二十二碳六烯酸（DHA），基于脂质的总重量，至少0.01重量％的n-3二十二碳烯酸（DPAn-3），基于 脂质，和至少0.01重量％ 基于脂质总重量的二十碳五烯酸（EPA），其中DHA，DPAn-3和EPA的总和低于1wt。 总脂质的百分比。
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公开(公告)号：US20120195975A1
公开(公告)日：2012-08-02
申请号：US13360508
申请日：2012-01-27
CPC分类号： A61K31/201 , A23L33/12 , A23L33/19 , A23L33/22 , A23L33/40 , A23V2002/00 , A61K31/702 , A61K31/7052 , A61K31/715 , A23V2250/28 , A23V2250/5046 , A23V2250/1872 , A23V2250/1874 , A23V2250/187 , A23V2250/1868 , A23V2250/1862 , A23V2250/5072
摘要： A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein is provided. The composition has a weight ratio of casein to whey between 1:1 to 1:2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. Methods of treatment by administering the composition are also provided.
摘要翻译： 提供了包含脂肪，蛋白质，碳水化合物，乳清和酪蛋白的营养或药物组合物。 该组合物的酪蛋白与乳清的重量比在1:1至1:2.4之间，包括：a）每100克蛋白质至少3克精氨酸; b）至少10wt。 ％亚油酸基于总脂肪酸; c）至少1wt。 基于总脂肪酸的％α亚麻酸; d）至少一种超过0.1重量％的长链多不饱和脂肪酸。 基于选自二十二碳六烯酸，花生四烯酸和二十碳五烯酸的总脂肪酸的％; e）5至25wt。 至少一种基于总脂肪酸的多不饱和脂肪酸的％; 和f）2至12克不可消化的低聚糖，其聚合度为每100克组合物干重2至100。 还提供了施用该组合物的治疗方法。
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公开(公告)号：US08580316B2
公开(公告)日：2013-11-12
申请号：US13360508
申请日：2012-01-27
CPC分类号： A61K31/201 , A23L33/12 , A23L33/19 , A23L33/22 , A23L33/40 , A23V2002/00 , A61K31/702 , A61K31/7052 , A61K31/715 , A23V2250/28 , A23V2250/5046 , A23V2250/1872 , A23V2250/1874 , A23V2250/187 , A23V2250/1868 , A23V2250/1862 , A23V2250/5072
摘要： A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein is provided. The composition has a weight ratio of casein to whey between 1:1 to 1:2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. Methods of treatment by administering the composition are also provided.
摘要翻译： 提供了包含脂肪，蛋白质，碳水化合物，乳清和酪蛋白的营养或药物组合物。 该组合物的酪蛋白与乳清的重量比在1:1至1:2.4之间，包括：a）每100克蛋白质至少3克精氨酸; b）至少10wt。 ％亚油酸基于总脂肪酸; c）至少1wt。 基于总脂肪酸的％α亚麻酸; d）至少一种超过0.1重量％的长链多不饱和脂肪酸。 基于选自二十二碳六烯酸，花生四烯酸和二十碳五烯酸的总脂肪酸的％; e）5至25wt。 至少一种基于总脂肪酸的多不饱和脂肪酸的％; 和2至12克不可消化的寡糖，其组合物的每100克干重具有聚合度为2至100。 还提供了施用组合物的治疗方法。
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公开(公告)号：US08114441B2
公开(公告)日：2012-02-14
申请号：US11660594
申请日：2005-08-19
CPC分类号： A61K31/201 , A23L33/12 , A23L33/19 , A23L33/22 , A23L33/40 , A23V2002/00 , A61K31/702 , A61K31/7052 , A61K31/715 , A23V2250/28 , A23V2250/5046 , A23V2250/1872 , A23V2250/1874 , A23V2250/187 , A23V2250/1868 , A23V2250/1862 , A23V2250/5072
摘要： A nutritional or pharmaceutical composition containing a fat component, a protein component and a carbohydrate component and comprising whey and casein. The composition has a weight ratio of casein to whey is 1:1 to 1:2.4 and that the composition contains: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids. The long chain polyunsaturated fatty acid being docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerization of 2 to 100 per 100 gram dry weight of the composition. The composition reduces—among others—the risks attached to feeding whey dominant infant formula.
摘要翻译： 一种含有脂肪组分，蛋白质组分和碳水化合物组分并包含乳清和酪蛋白的营养或药物组合物。 该组合物的酪蛋白与乳清的重量比为1:1至1:2.4，组合物含有：a）每100克蛋白质至少3克精氨酸; b）至少10wt。 ％亚油酸基于总脂肪酸; c）至少1wt。 基于总脂肪酸的％α亚麻酸; d）至少一种超过0.1重量％的长链多不饱和脂肪酸。 基于总脂肪酸的％。 长链多不饱和脂肪酸是二十二碳六烯酸，花生四烯酸和二十碳五烯酸; e）5至25wt。 至少一种基于总脂肪酸的多不饱和脂肪酸的％; 和f）2至12克不可消化的低聚糖，其聚合度为组合物每100克干重2至100。 组合物减少 - 其中包括喂食乳清主要婴儿配方奶粉的风险。
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公开(公告)号：US08053471B2
公开(公告)日：2011-11-08
申请号：US11666990
申请日：2005-11-11
CPC分类号： A61K31/202 , A23L33/12 , A23L33/22 , A23L33/40 , A23V2002/00 , A23V2250/187 , A23V2250/1868 , A23V2250/5046 , A23V2250/1872 , A23V2250/1874 , A23V2250/0644 , A23V2250/1642
摘要： The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition comprises a n-3 polyunsaturated fatty acid fraction containing at least 0.1 wt docosahexaenoic acid (DHA) based on total weight of the lipid, at least 0.01 wt % n-3 docosapentaenoic acid (DPAn-3) based on total weight of the lipid, and at least 0.01 wt. % eicosapentaenoic acid (EPA) based on total weight of the lipid, wherein the sum of DHA, DPAn-3 and EPA is below 1 wt. % of total lipid.
摘要翻译： 本发明涉及长链多不饱和脂肪酸用于制造用于喂养怀孕期间代谢紊乱的母亲的婴儿的营养组合物和相应组合物的用途。 所述组合物包含n-3多不饱和脂肪酸级分，其含有至少0.1重量％的二十二碳六烯酸（DHA），基于脂质的总重量，至少0.01重量％的n-3二十二碳烯酸（DPAn-3），基于 脂质，和至少0.01重量％ 基于脂质总重量的二十碳五烯酸（EPA），其中DHA，DPAn-3和EPA的总和低于1wt。 总脂质的百分比。
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公开(公告)号：US20070098762A1
公开(公告)日：2007-05-03
申请号：US10576834
申请日：2004-10-25
申请人： Bernd Stahl , Laura M'Rabet , Arjan Vos , Johan Garssen , Gunther Boehm
发明人： Bernd Stahl , Laura M'Rabet , Arjan Vos , Johan Garssen , Gunther Boehm
IPC分类号： A61K31/715 , A61K47/00
CPC分类号： A61K31/732 , A23L29/30 , A23L33/10 , A23L33/125 , A23L33/40 , A23V2002/00 , A61K31/70 , A61K31/702 , A23V2200/324 , A23V2250/28
摘要： The present invention relates to a method for enhancing the immune system and the treatment and/or prevention of immune system related disorders in a mammal, particularly newborns, said method comprising the administration of acid oligosaccharide and neutral oligosaccharide. Food compositions suitable for use in the above method are also provided.
摘要翻译： 本发明涉及增强哺乳动物，特别是新生儿免疫系统和治疗和/或预防免疫系统相关疾病的方法，所述方法包括施用酸性寡糖和中性寡糖。 还提供了适用于上述方法的食品组合物。
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8.发明申请COMPOSITION CONTAINING OLIGOSACCHARIDES FOR THE TREATMENT/PREVENTION OF INFECTIONS 审中-公开含有治疗/预防感染的低聚糖的组合物公开(公告)号：US20090156550A1
公开(公告)日：2009-06-18
申请号：US12096573
申请日：2005-12-06
IPC分类号： A61K31/715
CPC分类号： A61K31/702 , A23L29/231 , A23L29/244 , A23L33/40 , A23V2002/00 , A61K31/70 , Y02A50/475 , A23V2200/324 , A23V2250/28 , A23V2250/5072
摘要： The present invention relates to the use of oligosaccharide mixtures for the treatment and/or prevention of infections, in particular for reducing the severity of childhood infection or the treatment and/or prevention of childhood infection.
摘要翻译： 本发明涉及寡糖混合物用于治疗和/或预防感染的用途，特别是用于降低儿童感染的严重性或治疗和/或预防儿童感染。
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公开(公告)号：US20080124323A1
公开(公告)日：2008-05-29
申请号：US11574180
申请日：2005-08-24
申请人： Gunther Boehm , Laura M'Rabet , Bernd Stahl , Johan Garssen
发明人： Gunther Boehm , Laura M'Rabet , Bernd Stahl , Johan Garssen
IPC分类号： A61K31/733 , A61K31/715 , A61K45/00 , A61K39/42 , A61P11/00
CPC分类号： A61K31/702 , A23L33/12 , A23L33/21 , A23L33/40 , A23V2002/00 , A23Y2300/29 , A61K31/202 , A61K31/733 , A61K35/741 , A61K39/42 , A61K2300/00 , A23V2200/324 , A23V2250/28 , A23V2250/608 , A23V2250/304 , A23V2250/1642 , A23V2250/1882 , A23V2200/3202 , A23V2200/3204
摘要： The present invention provides a method and composition for the treatment and/or prevention of respiratory tract infection and/or respiratory tract infection disease, said method comprising orally administering a composition to a mammal, said composition comprising a galactose containing indigestible oligosaccharide and at least 5 wt. % digestible galactose saccharide.
摘要翻译： 本发明提供了一种用于治疗和/或预防呼吸道感染和/或呼吸道感染疾病的方法和组合物，所述方法包括向哺乳动物口服施用组合物，所述组合物包含含有不可消化的寡糖的半乳糖和至少5 重量 ％消化半乳糖。
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公开(公告)号：US20100136134A1
公开(公告)日：2010-06-03
申请号：US11660594
申请日：2005-08-19
CPC分类号： A61K31/201 , A23L33/12 , A23L33/19 , A23L33/22 , A23L33/40 , A23V2002/00 , A61K31/702 , A61K31/7052 , A61K31/715 , A23V2250/28 , A23V2250/5046 , A23V2250/1872 , A23V2250/1874 , A23V2250/187 , A23V2250/1868 , A23V2250/1862 , A23V2250/5072
摘要： A nutritional or pharmaceutical composition containing a fat component, a protein component and a carbohydrate component and comprising whey and casein. The composition has a weight ratio of casein to whey is 1:1 to 1:2.4 and that the composition contains: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids. The long chain polyunsaturated fatty acid being docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. The composition reduces—among others—the risks attached to feeding whey dominant infant formula.
摘要翻译： 一种含有脂肪组分，蛋白质组分和碳水化合物组分并包含乳清和酪蛋白的营养或药物组合物。 该组合物的酪蛋白与乳清的重量比为1:1至1:2.4，组合物含有：a）每100克蛋白质至少3克精氨酸; b）至少10wt。 ％亚油酸基于总脂肪酸; c）至少1wt。 基于总脂肪酸的％α亚麻酸; d）至少一种超过0.1重量％的长链多不饱和脂肪酸。 基于总脂肪酸的％。 长链多不饱和脂肪酸是二十二碳六烯酸，花生四烯酸和二十碳五烯酸; e）5至25wt。 至少一种基于总脂肪酸的多不饱和脂肪酸的％; 和f）2至12克不可消化的低聚糖，其聚合度为每100克组合物干重2至100。 组合物减少 - 其中包括喂食乳清主要婴儿配方奶粉的风险。
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