MICROCAPSULES WITH POLYMERIC COATING COMPRISING A LIPID AND AN ACTIVE AGENT
    10.
    发明申请
    MICROCAPSULES WITH POLYMERIC COATING COMPRISING A LIPID AND AN ACTIVE AGENT 审中-公开
    具有包含脂质和活性剂的聚合物涂层的微胶囊

    公开(公告)号:US20170000741A1

    公开(公告)日:2017-01-05

    申请号:US15106476

    申请日:2014-12-19

    摘要: The present invention relates to microcapsules and to methods for preparing them. The microcapsules comprise a polymeric coating that is at least partly crosslinked with a polymeric matrix comprising a polysaccharide. In the matrix, a lipid and an active agent or a prodrug or salt thereof are embedded, the lipid preferably having a melting point of at least 30° C. The microcapsules can be used as a medicament, dietary supplement or food additive, the microcapsules comprising a polymeric coating that is at least partly crosslinked with a polymeric matrix comprising a polysaccharide. As above, a lipid and an active agent or a prodrug or salt thereof are embedded in the matrix, with the lipid preferably having a melting point of at least 30° C. Methods for treating diarrhea or preventing colon cancer comprising administering such microcapsules are also disclosed.

    摘要翻译: 本发明涉及微胶囊及其制备方法。 微胶囊包含至少部分与包含多糖的聚合物基质部分交联的聚合物涂层。 在基质中,嵌入了脂质和活性剂或其前体药物或其盐,脂质优选具有至少30℃的熔点。微胶囊可用作药物,膳食补充剂或食品添加剂,微胶囊 包括与包含多糖的聚合物基质至少部分交联的聚合物涂层。 如上所述,脂质和活性剂或其前药或盐嵌入基质中,脂质优选具有至少30℃的熔点。治疗腹泻或预防结肠癌的方法包括施用这种微胶囊也是 披露