利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

16 条记录 (耗时 0.034 秒)

    Process for the large scale production of rabies vaccine
    4.
    发明授权
    Process for the large scale production of rabies vaccine 失效
    大规模生产狂犬病疫苗的过程

    公开(公告)号：US4664912A

    公开(公告)日：1987-05-12

    申请号：US656762

    申请日：1984-10-01

    申请人： Tadeusz J. Wiktor ,  Bernard J. Fanget ,  Pierre Fournier ,  Bernard J. Montagnon

    发明人： Tadeusz J. Wiktor ,  Bernard J. Fanget ,  Pierre Fournier ,  Bernard J. Montagnon

    IPC分类号： A61K39/205 ,  C12N7/00 ,  C12N7/08

    CPC分类号： A61K39/205 ,  A61K39/12 ,  A61K2039/5252 ,  C12N2760/20134

    摘要： In the large-scale production of rabies vaccine a cell stock comprising a VERO cell strain and a liquid nutritive medium containing serum and microcarriers suspended therein is successively passed into biogenerators of increasing volume. The last of the passages is carried out in a biogenerator having a volume of at least 150 liters. The liquid nutritive medium is drawn off at the end of the final passage and replaced with a serum-free liquid nutritive medium. The cell stock is inoculated in the last passage biogenerator with virus which is allowed to develop. The virus is then cultured, withdrawn and filtered. The filtered liquid suspension is then ultrafiltered, with inactivated beta-propiolactone and purified by zonal centrifugation or chromatography.

    摘要翻译： 在狂犬病疫苗的大规模生产中，包含VERO细胞株和含有悬浮于其中的血清和微载体的液体营养培养基的细胞储存液依次进入增加体积的生物发生器中。 最后的通道在具有至少150升的体积的生物发生器中进行。 液体营养培养基在最终通道的末端被抽出并用无血清的液体营养培养基代替。 将细胞储存液接种在最后一代有生物发生器的病毒中。 然后将病毒培养，取出并过滤。 然后将经过滤的液体悬浮液进行超滤，用灭活的β-丙内酯，并通过区域离心或色谱纯化。

    Polyphonic note detection
    6.
    发明授权
    Polyphonic note detection 有权
    复音笔记检测

    公开(公告)号：US08309834B2

    公开(公告)日：2012-11-13

    申请号：US12758675

    申请日：2010-04-12

    申请人： Steffen Gehring ,  Markus Sapp ,  Pierre Fournier

    发明人： Steffen Gehring ,  Markus Sapp ,  Pierre Fournier

    IPC分类号： G10H1/38

    CPC分类号： G10H1/383 ,  G10H2210/066 ,  G10H2220/091 ,  G10H2250/235

    摘要： Processor-implemented methods and systems for polyphonic note detection are disclosed. The method includes converting a portion of a polyphonic audio signal from a time domain to a frequency domain. The method includes detecting a fundamental frequency peak in the frequency domain. The method then detects a defined number of integer-interval harmonic partials. If a defined number of integer-interval harmonic partials relative to the fundamental frequency peak are detected the fundamental frequency is recorded as a detected note. This process is repeated for each fundamental frequency until each note in the polyphonic audio signal has been detected. For example, this method allows detection of each note in a strummed guitar chord to provide feedback on the tuning of each string in a strummed chord or allows detection and feedback of the timing and pitch errors for guitar chords played along with a reference track.

    摘要翻译： 公开了用于复音音符检测的处理器实现的方法和系统。 该方法包括将来自时域的多音音频信号的一部分转换为频域。 该方法包括检测频域中的基频峰值。 该方法然后检测定义数量的整数间隔谐波分量。 如果检测到相对于基频峰值的定义数量的整数间隔谐波部分，则将基频记录为检测到的音符。 对于每个基本频率重复该过程，直到已经检测到复音音频信号中的每个音符。 例如，该方法允许检测吉他弦中的每个音符，以提供对弦弦中的每个弦的调谐的反馈，或允许检测和反馈与参考轨道一起播放的吉他和弦的定时和俯仰误差。