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公开(公告)号：US12071340B2
公开(公告)日：2024-08-27
申请号：US17700299
申请日：2022-03-21
发明人： Han Cao , Michael David Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
CPC分类号： B81C1/00119 , B01L3/502761 , B01L2200/0663 , B01L2200/0689 , B01L2200/10 , B01L2300/0816 , B01L2300/0851 , B01L2300/0858 , B01L2300/0864 , B01L2300/0887 , B01L2300/168 , B01L2400/0415 , B01L2400/043 , B01L2400/0442 , B01L2400/0487 , B01L2400/086 , B81B2201/058 , B81C2201/019 , G01N2021/0346 , G01N2021/6439 , Y10T29/4981
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided.
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公开(公告)号：US20220388838A1
公开(公告)日：2022-12-08
申请号：US17700299
申请日：2022-03-21
发明人： Han Cao , Michael David Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided
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公开(公告)号：US11529630B2
公开(公告)日：2022-12-20
申请号：US16889256
申请日：2020-06-01
IPC分类号： B01L3/00 , G01N27/447 , C12Q1/6869 , G01N33/487 , B82Y30/00 , G01N35/10
摘要： Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed. Also disclosed are methods for fabricating such devices and for analyzing macromolecules using such devices.
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4.发明申请NANONOZZLE DEVICE ARRAYS: THEIR PREPARATION AND USE FOR MACROMOLECULAR ANALYSIS 有权纳米器件阵列：其制备和用于大分子分析公开(公告)号：US20150323518A1
公开(公告)日：2015-11-12
申请号：US14712816
申请日：2015-05-14
IPC分类号： G01N33/487 , G01N27/447 , C12Q1/68
CPC分类号： B82Y30/00 , B01L3/502761 , B01L2200/0663 , B01L2200/12 , B01L2300/0645 , B01L2300/0816 , B01L2300/0822 , B01L2300/0896 , B01L2400/0415 , B01L2400/0487 , C12Q1/6869 , G01N27/447 , G01N33/48721 , G01N2035/1039 , Y10T436/143333 , Y10T436/2575 , C12Q2565/631
摘要： Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed. Also disclosed are methods for fabricating such devices and for analyzing macromolecules using such devices.
摘要翻译： 公开了适用于分析大分子结构（包括DNA测序）的约束纳米通道装置。 还公开了制造这种装置和使用这种装置分析大分子的方法。
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公开(公告)号：US20230126737A1
公开(公告)日：2023-04-27
申请号：US18056074
申请日：2022-11-16
IPC分类号： B01L3/00 , G01N27/447 , C12Q1/6869 , G01N33/487 , B82Y30/00
摘要： Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed. Also disclosed are methods for fabricating such devices and for analyzing macromolecules using such devices.
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公开(公告)号：US11292713B2
公开(公告)日：2022-04-05
申请号：US16864551
申请日：2020-05-01
发明人： Han Cao , Michael David Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided.
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公开(公告)号：US20170313580A1
公开(公告)日：2017-11-02
申请号：US15385302
申请日：2016-12-20
发明人： Han Cao , Michael David Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
CPC分类号： B81C1/00119 , B01L3/502761 , B01L2200/0663 , B01L2200/0689 , B01L2200/10 , B01L2300/0816 , B01L2300/0851 , B01L2300/0858 , B01L2300/0864 , B01L2300/0887 , B01L2300/168 , B01L2400/0415 , B01L2400/043 , B01L2400/0442 , B01L2400/0487 , B01L2400/086 , B81B2201/058 , B81C2201/019 , G01N2021/0346 , G01N2021/6439 , Y10T29/4981
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided.
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公开(公告)号：US20210101796A1
公开(公告)日：2021-04-08
申请号：US16864551
申请日：2020-05-01
发明人： Han Cao , Michael David Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided
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公开(公告)号：US10654715B2
公开(公告)日：2020-05-19
申请号：US15385302
申请日：2016-12-20
发明人： Han Cao , Michael David Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided.
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公开(公告)号：US20180290885A1
公开(公告)日：2018-10-11
申请号：US15801081
申请日：2017-11-01
IPC分类号： B82Y30/00 , C12Q1/6869 , B01L3/00 , G01N33/487 , G01N27/447 , G01N35/10
摘要： Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed. Also disclosed are methods for fabricating such devices and for analyzing macromolecules using such devices.
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