中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

61 records (took 0.028 seconds)

    Compact multimodality optical coherence tomography imaging systems having a ring of optical fibers in image capture path
    5.
    发明授权
    Compact multimodality optical coherence tomography imaging systems having a ring of optical fibers in image capture path 有权
    具有图像捕捉路径中的光纤环的紧凑型多模光学相干断层成像系统

    公开(公告)号：US09585556B2

    公开(公告)日：2017-03-07

    申请号：US15054714

    申请日：2016-02-26

    Applicant: Bioptigen, Inc.

    Inventor： Eric L. Buckland ,  Bradley A. Bower ,  Robert H. Hart ,  Pete Huening

    IPC: G01B9/02 ,  A61B3/10 ,  A61B3/14

    CPC classification number: A61B3/102 ,  A61B3/14 ,  G01B9/0203 ,  G01B9/02091

    Abstract: Systems for imaging a sample are provided. The system includes an OCT imaging portion having an associated OCT path defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path defined by a second set of optical elements between an image capture device and the sample; and an illuminator portion having an associated illumination path defined by a third set of optical elements between an illumination source and the sample. The OCT path, the image capture path, and the illuminator path have at least one optical element in common, and the respective paths differ from each other by at least one optical element. The illumination path includes a multi-wavelength source of optical radiation.

    Abstract translation: 提供了用于成像样本的系统。 该系统包括OCT成像部分，其具有由OCT信号传送光纤和样本之间的一组光学元件限定的相关OCT路径; 具有由图像捕获装置和样本之间的第二组光学元件限定的相关联的图像捕获路径的图像捕获部分; 以及具有由照明源和样品之间的第三组光学元件限定的相关联的照明路径的照明器部分。 OCT路径，图像捕获路径和照明器路径具有共同的至少一个光学元件，并且相应的路径由至少一个光学元件彼此不同。 照明路径包括多波长的光辐射源。

    Image Registration, Averaging, and Compounding for High Speed Extended Depth Optical Coherence Tomography
    6.
    发明申请
    Image Registration, Averaging, and Compounding for High Speed Extended Depth Optical Coherence Tomography 审中-公开
    图像配准，平均和复合高速扩展深度光学相干断层扫描

    公开(公告)号：US20160298953A1

    公开(公告)日：2016-10-13

    申请号：US15190299

    申请日：2016-06-23

    Applicant: Bioptigen, Inc.

    Inventor： Eric L. Buckland ,  Al-Hafeez Z. Dhalla ,  Nestor O. Farmiga ,  Mehran Ghofrani ,  Robert H. Hart ,  Andrew Murnan ,  Christopher Saxer

    IPC: G01B9/02 ,  A61B3/10

    CPC classification number: G01B9/02087 ,  A61B3/102 ,  G01B9/02004 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091

    Abstract: An optical coherence tomography (OCT) system including a source of broadband optical radiation and a beamsplitter coupled to the source is provided. The beamsplitter divides the source radiation into a reference path and a sample path. The reference path includes an optical switch to switch the reference path between a first path having a first reference reflection at a first reference optical path length and a second path having a second reference reflection at a second reference optical path length. The system further includes a beam combiner that mixes source radiation reflected from a subject in the sample path with source radiation returned from the first reference reflection and the second reference reflection. A detection system detects a first wavelength dependent interferogram during the first time interval and a second wavelength dependent interferogram during the second time interval. A processor preconditions the first and second wavelength dependent interferograms.

    Abstract translation: 提供了包括宽带光辐射源和耦合到源的分束器的光学相干断层摄影（OCT）系统。 分束器将源辐射分为参考路径和采样路径。 参考路径包括光开关，用于在具有第一参考光路长度的第一参考反射的第一路径和具有第二参考光路长度的第二参考反射的第二路径之间切换参考路径。 该系统还包括一个光束组合器，它将从样本路径中的被摄体反射的源辐射与从第一参考反射和第二参考反射返回的源辐射混合。 检测系统在第一时间间隔期间检测第一波长相关干涉图，并且在第二时间间隔期间检测第二波长相关干涉图。 处理器预处理第一和第二波长依赖干涉图。

    Compact Multimodality Optical Coherence Tomography Imaging Systems
    7.
    发明申请
    Compact Multimodality Optical Coherence Tomography Imaging Systems 审中-公开
    紧凑型多光学相干层析成像系统

    公开(公告)号：US20150103355A1

    公开(公告)日：2015-04-16

    申请号：US14551916

    申请日：2014-11-24

    Applicant: Bioptigen, Inc.

    Inventor： Bradley A. Bower ,  Robert H. Hart ,  Pete Huening ,  Eric L. Buckland

    IPC: A61B3/10 ,  A61B3/14 ,  G01B9/02

    CPC classification number: A61B3/102 ,  A61B3/14 ,  G01B9/0203 ,  G01B9/02091

    Abstract: Systems for imaging a sample are provided. The system includes an optical coherence tomography (OCT) imaging portion having an associated OCT path defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path defined by a second set of optical elements between an image capture device and the sample, different from the OCT path; and an illuminator portion having an associated illumination path defined by a third set of optical elements between an illumination source and the sample. The OCT path, the image capture path, and the illuminator path have at least one optical element in common, and the respective paths differ from each other by at least one optical element. The OCT path and the image capture path share a common intermediate conjugate image plane. Focal control is achieved for the OCT path and the image capture path concurrently through adjustment of one or more common optical elements distal to the common intermediate conjugate plane, such that focal control requires no differential adjustment between optical elements not in common to both paths.

    Abstract translation: 提供了用于成像样本的系统。 该系统包括光学相干断层摄影（OCT）成像部分，其具有由OCT信号传送光纤和样本之间的一组光学元件限定的相关OCT路径; 图像捕获部分，具有由图像捕获装置和样本之间的不同于OCT路径的第二组光学元件定义的相关联的图像捕获路径; 以及具有由照明源和样品之间的第三组光学元件限定的相关联的照明路径的照明器部分。 OCT路径，图像捕获路径和照明器路径具有共同的至少一个光学元件，并且相应的路径由至少一个光学元件彼此不同。 OCT路径和图像捕获路径共享一个共同的中间共轭图像平面。 通过调整远离公共中间共轭平面的一个或多个共同的光学元件，通过同时进行OCT路径和图像捕获路径的焦点控制，使得焦点控制不需要在两个路径不共同的光学元件之间进行差分调整。

    Procedural Optical Coherence Tomography (OCT) for Surgery and Related Systems and Methods
    8.
    发明申请
    Procedural Optical Coherence Tomography (OCT) for Surgery and Related Systems and Methods 审中-公开
    手术相关系统和方法的程序性光学相干断层扫描（OCT）

    公开(公告)号：US20150031993A1

    公开(公告)日：2015-01-29

    申请号：US14446013

    申请日：2014-07-29

    Applicant: Bioptigen, Inc.

    Inventor： Eric L. Buckland ,  AI-Hafeez Dhalla ,  Robert H. Hart

    IPC: A61B3/10 ,  A61F2/16 ,  A61B3/107

    Abstract: Methods for performing a surgical procedure using optical coherence tomography (OCT) are provided. The method includes orienting the subject for the surgical procedure, wherein orienting comprises imaging a region of the subject that contains a structure having a known orientational asymmetry, testing the image for the presence and location of the structure, and confirming correct orientation of the subject using the OCT image of the structure having the known orientational asymmetry; obtaining at least one image of the surgical region of the subject using OCT and constructing an initial structural view of the surgical region; computing at least one clinical parameter relevant as an end point for assessing the outcome of the surgical procedure using data derived from the OCT image; periodically assessing a surgical process and monitoring clinical outcomes related to the surgical procedure using changes to the OCT-derived structural view of the surgical region OCT or the changes to the computed clinical parameters derived from the at least an OCT image; determining if a surgical plan for the surgical procedure needs modification based on the periodic assessment and/or monitoring; modifying the surgical plan for the surgical procedure if it is determined modification is needed; and repeatedly assessing and monitoring, determining and modifying until it is determined that modification is not needed.

    Abstract translation: 提供了使用光学相干断层扫描（OCT）进行外科手术的方法。 该方法包括使被检体定向于外科手术，其中定向包括成像包含具有已知取向不对称性的结构的受试者的区域，测试该图像的结构的存在和位置，以及使用 具有已知取向不对称性的结构的OCT图像; 使用OCT获得所述受试者的手术区域的至少一个图像，并且构建所述手术区域的初始结构图; 计算至少一个临床参数，作为使用从OCT图像得到的数据来评估外科手术结果的终点; 周期性地评估外科手术过程并且使用对来自手术区域OCT的OCT衍生的结构视图的改变或由至少OCT图像导出的计算的临床参数的变化来监测与外科手术相关的临床结果; 确定外科手术手术方案是否需要基于定期评估和/或监测进行修改; 如果需要修改，则修改外科手术的手术计划; 并重复评估和监测，确定和修改，直到确定不需要修改为止。

Patent Agency Ranking