公开(公告)号：US08205782B2

公开(公告)日：2012-06-26

申请号：US12373450

申请日：2007-07-12

申请人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle ,  Boaz Shenhav ,  Kobby Greenberg

发明人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle ,  Boaz Shenhav ,  Kobby Greenberg

IPC分类号： A61B17/04

CPC分类号： A61B17/0643 ,  A61B17/115 ,  A61B17/32053 ,  A61B2017/0641

摘要： A compression assembly for use in compressing tissue comprising a first portion which includes a first compression element and a second portion which comprises a second compression element, at least one support element, and at least one spring element. Typically the spring element is formed of a shape-memory material. The at least one spring element is in compressive force contact with the second compression element and the tissue to be joined is positioned between the first and second compression elements. A plurality of needles on one of the support elements is operative to pierce the tissue and the first portion of the assembly, holding the first compression element to the second portion of the assembly. The invention is appropriate for joining severed tissue in anastomosis procedures or closing natural or surgically produced tissue perforations.

摘要翻译： 一种用于压缩组织的压缩组件，包括包括第一压缩元件的第一部分和包括第二压缩元件，至少一个支撑元件和至少一个弹簧元件的第二部分。 通常，弹簧元件由形状记忆材料形成。 所述至少一个弹簧元件与第二压缩元件压缩力接触，并且待连接的组织定位在第一和第二压缩元件之间。 一个支撑元件上的多个针可操作以刺穿组织和组件的第一部分，将第一压缩元件保持在组件的第二部分。 本发明适用于在吻合过程中连接切断的组织或闭合天然或手术产生的组织穿孔。

公开(公告)号：US07635374B2

公开(公告)日：2009-12-22

申请号：US11647912

申请日：2006-12-29

申请人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

发明人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

IPC分类号： A61B17/10 ,  A61B17/08 ,  A61B1/00

CPC分类号： A61B17/0643 ,  A61B1/00135 ,  A61B1/0014 ,  A61B1/018 ,  A61B17/068 ,  A61B17/12 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/0641 ,  A61B2017/308

摘要： A system including surgical compression clips is described and used for endoscopic full thickness resection. Similarly, methods for endoscopic full thickness resection using the described system are also discussed. Surgical compression clips using shape-memory elements are discussed. These clips are advanceable to the site of suspect tissue to be resected through a lumen of a multi-lumen sleeve encasing an endoscope. At the site of the tissue, the compression clip is opened and operated to circumscribe the suspect tissue. Grasper assemblies, advanceable through an endoscope, are also described. These latter grasp and bring the suspect tissue to the open clip. The clip is then closed and the tissue resected. The clip effects necrosis and healing at the resected site.

摘要翻译： 描述了一种包括手术压缩夹的系统，用于内窥镜全厚度切除。 类似地，还讨论了使用所述系统的内窥镜全厚度切除术的方法。 讨论使用形状记忆元件的手术压缩夹。 这些夹子可推进到可疑组织的位置，以通过包围内窥镜的多腔套筒的内腔切除。 在组织的位置处，压缩夹被打开并操作以包围可疑组织。 还描述了可通过内窥镜推进的抓斗组件。 这些后者将把嫌疑组织带到打开的夹子上。 然后关闭夹子并切除组织。 夹子会影响切除部位的坏死和愈合。

公开(公告)号：US20070213747A1

公开(公告)日：2007-09-13

申请号：US11647913

申请日：2006-12-29

申请人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

发明人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

IPC分类号： A61B17/08

CPC分类号： A61B17/12 ,  A61B1/0014 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/0641 ,  A61B2017/308

摘要： A surgical clip assembly which includes a pair of generally linear compression elements for securing tissue between them and for applying to the secured tissue a compression force. The clip assembly has an initial, open position in which the linear compression elements may be positioned about tissue to be secured between them. The assembly also has a final, closed position where the compression elements are substantially parallel to each other, applying a compressive force to the secured tissue. The clip assembly also includes a force means disposed between the pair of compression elements and operative to transmit operational forces between them.

摘要翻译： 一种外科夹子组件，其包括一对大致线性的压缩元件，用于将组织固定在它们之间并用于向固定的组织施加压缩力。 夹子组件具有初始的打开位置，其中线性压缩元件可以围绕组织定位以固定在它们之间。 组件还具有最终的闭合位置，其中压缩元件基本上彼此平行，向固定的组织施加压缩力。 夹子组件还包括设置在该对压缩元件之间并且可操作地在它们之间传递操作力的力装置。

公开(公告)号：US20100331862A1

公开(公告)日：2010-12-30

申请号：US12521597

申请日：2007-12-27

申请人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

发明人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

IPC分类号： A61B17/10 ,  A61B17/08

CPC分类号： A61B17/12 ,  A61B1/0014 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/0641 ,  A61B2017/308

摘要： A compression clip system where compression is used to close a tissue opening, reduce the volume of an organ, ligate dilated blood vessels or compress tissue adjacent to various other types of lesions to induce healing. Compression prevents bleeding and the leakage of body fluids into a body cavity. The opening may be surgery induced as in gastrectomies or formed naturally such as peptic ulcers and hemorrhoids. The system may include a compression clip, a suitable clip applier, a grasper assembly and an endoscope all brought to the compression site via a multi-lumen sleeve.

摘要翻译： 压缩夹系统，其中压缩用于封闭组织开口，减少器官的体积，连接扩张的血管或压迫与各种其它类型的损伤相邻的组织以诱导愈合。 压缩防止体液流入体腔的出血和泄漏。 开口可以是胃切除手术或自然形成的手术，如消化性溃疡和痔疮。 该系统可以包括压缩夹，合适的施夹器，抓紧器组件和内窥镜，其全部通过多腔套筒带到压缩部位。

公开(公告)号：US20070213585A1

公开(公告)日：2007-09-13

申请号：US11647912

申请日：2006-12-29

申请人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

发明人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

IPC分类号： A61B1/00

CPC分类号： A61B17/0643 ,  A61B1/00135 ,  A61B1/0014 ,  A61B1/018 ,  A61B17/068 ,  A61B17/12 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/0641 ,  A61B2017/308

摘要： A system including surgical compression clips is described and used for endoscopic full thickness resection. Similarly, methods for endoscopic full thickness resection using the described system are also discussed. Surgical compression clips using shape-memory elements are discussed. These clips are advanceable to the site of suspect tissue to be resected through a lumen of a multi-lumen sleeve encasing an endoscope. At the site of the tissue, the compression clip is opened and operated to circumscribe the suspect tissue. Grasper assemblies, advanceable through an endoscope, are also described. These latter grasp and bring the suspect tissue to the open clip. The clip is then closed and the tissue resected. The clip effects necrosis and healing at the resected site.

摘要翻译： 描述了一种包括手术压缩夹的系统，用于内窥镜全厚度切除。 类似地，还讨论了使用所述系统的内窥镜全厚度切除术的方法。 讨论使用形状记忆元件的手术压缩夹。 这些夹子可推进到可疑组织的位置，以通过包围内窥镜的多腔套筒的内腔切除。 在组织的位置处，压缩夹被打开并操作以包围可疑组织。 还描述了可通过内窥镜推进的抓斗组件。 这些后者将把嫌疑组织带到打开的夹子上。 然后关闭夹子并切除组织。 夹子会影响切除部位的坏死和愈合。

公开(公告)号：US07892244B2

公开(公告)日：2011-02-22

申请号：US11647913

申请日：2006-12-29

申请人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

发明人： Leonid Monassevitch ,  Boaz Shenhav ,  Boaz Harari ,  Amir Perle ,  Michael Arad ,  Shahar Millis ,  Kobby Greenberg ,  Alex Geller ,  Amir Szold ,  Shlomo Lelcuk ,  Doron Kopelman ,  Amol Bapaye ,  Dror Rosner

IPC分类号： A61B17/08

CPC分类号： A61B17/12 ,  A61B1/0014 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/0641 ,  A61B2017/308

摘要： A surgical clip assembly which includes a pair of generally linear compression elements for securing tissue between them and for applying to the secured tissue a compression force. The clip assembly has an initial, open position in which the linear compression elements may be positioned about tissue to be secured between them. The assembly also has a final, closed position where the compression elements are substantially parallel to each other, applying a compressive force to the secured tissue. The clip assembly also includes a force means disposed between the pair of compression elements and operative to transmit operational forces between them.

摘要翻译： 一种外科夹子组件，其包括一对大致线性的压缩元件，用于将组织固定在它们之间并用于向固定的组织施加压缩力。 夹子组件具有初始的打开位置，其中线性压缩元件可以围绕组织定位以固定在它们之间。 组件还具有最终的闭合位置，其中压缩元件基本上彼此平行，向固定的组织施加压缩力。 夹子组件还包括设置在该对压缩元件之间并且可操作地在它们之间传递操作力的力装置。

公开(公告)号：US20090302089A1

公开(公告)日：2009-12-10

申请号：US12373450

申请日：2007-07-12

申请人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle ,  Boaz Shenhav ,  Kobby Greenberg

发明人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle ,  Boaz Shenhav ,  Kobby Greenberg

IPC分类号： A61B17/04

CPC分类号： A61B17/0643 ,  A61B17/115 ,  A61B17/32053 ,  A61B2017/0641

摘要： A compression assembly for use in compressing tissue comprising a first portion which includes a first compression element and a second portion which comprises a second compression element, at least one support element, and at least one spring element. Typically the spring element is formed of a shape-memory material. The at least one spring element is in compressive force contact with the second compression element and the tissue to be joined is positioned between the first and second compression elements. A plurality of needles on one of the support elements is operative to pierce the tissue and the first portion of the assembly, holding the first compression element to the second portion of the assembly. The invention is appropriate for joining severed tissue in anastomosis procedures or closing natural or surgically produced tissue perforations.

摘要翻译： 一种用于压缩组织的压缩组件，包括包括第一压缩元件的第一部分和包括第二压缩元件，至少一个支撑元件和至少一个弹簧元件的第二部分。 通常，弹簧元件由形状记忆材料形成。 所述至少一个弹簧元件与第二压缩元件压缩力接触，并且待连接的组织定位在第一和第二压缩元件之间。 一个支撑元件上的多个针可操作以刺穿组织和组件的第一部分，将第一压缩元件保持在组件的第二部分。 本发明适用于在吻合过程中连接切断的组织或闭合天然或手术产生的组织穿孔。

公开(公告)号：US07527185B2

公开(公告)日：2009-05-05

申请号：US11485604

申请日：2006-07-12

申请人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle

发明人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle

IPC分类号： A61B17/08

CPC分类号： A61B17/115 ,  A61B17/0643 ,  A61B17/1155 ,  A61B17/32053 ,  A61B2017/0641

摘要： A compression anastomosis ring (CAR) assembly for use in joining severed organ wall portions of a hollow organ. The assembly comprises a first portion which includes an anvil assembly and a second portion which comprises a bottom ring, at least one ring element, and at least one spring element formed of a shape-memory alloy. The at least one spring element provides a restorative force and is in compressive force contact with the bottom ring and the tissue to be joined is positioned between the anvil ring and the bottom ring. A plurality of needles on one of the ring elements is operative, upon application of a closure force, to pierce the tissue and the anvil ring, holding the anvil ring to the second portion of the CAR assembly. An applicator for applying the CAR assembly and a method for using the assembly and applicator are taught.

摘要翻译： 压缩吻合环（CAR）组件，用于连接中空器官的切断的器官壁部分。 组件包括包括砧组件的第一部分和包括底环，至少一个环形元件和由形状记忆合金形成的至少一个弹簧元件的第二部分。 所述至少一个弹簧元件提供修复力并且与所述底环压缩力接触，并且待连接的组织位于所述砧座环和所述底环之间。 一个环形元件上的多个针在施加闭合力时可操作以刺穿组织和砧座环，将砧座环保持在CAR组件的第二部分。 教导了用于施加CAR组件的施加器和使用组件和涂敷器的方法。

公开(公告)号：US20080015617A1

公开(公告)日：2008-01-17

申请号：US11485604

申请日：2006-07-12

申请人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle

发明人： Boaz Harari ,  Leonid Monassevitch ,  Michael Arad ,  Doron Kopelman ,  Amir Perle

IPC分类号： A61B17/08

CPC分类号： A61B17/115 ,  A61B17/0643 ,  A61B17/1155 ,  A61B17/32053 ,  A61B2017/0641

摘要： A compression anastomosis ring (CAR) assembly for use in joining severed organ wall portions of a hollow organ. The assembly comprises a first portion which includes an anvil ring and a second portion which comprises a bottom ring, at least one ring element, and at least one spring element formed of a shape-memory alloy. The at least one spring element provides a restorative force and is in compressive force contact with the bottom ring and the tissue to be joined is positioned between the anvil ring and the bottom ring. A plurality of needles on one of the ring elements is operative, upon application of a closure force, to pierce the tissue and the anvil ring, holding the disk to the second portion of the CAR assembly. An applicator for applying the CAR assembly and a method for using the assembly and applicator are taught.

摘要翻译： 压缩吻合环（CAR）组件，用于连接中空器官的切断的器官壁部分。 组件包括包括砧座环的第一部分和包括底环，至少一个环形元件和由形状记忆合金形成的至少一个弹簧元件的第二部分。 所述至少一个弹簧元件提供修复力并且与所述底环压缩力接触，并且待连接的组织位于所述砧座环和所述底环之间。 一个环形元件上的多个针在施加闭合力时可操作以刺穿组织和砧座环，将盘保持在CAR组件的第二部分。 教导了用于施加CAR组件的施加器和使用组件和涂敷器的方法。

公开(公告)号：US06896684B2

公开(公告)日：2005-05-24

申请号：US10158673

申请日：2002-05-30

申请人： Leonid Monassevitch ,  Shlomo Lelcuk ,  Michael Arad ,  Boaz Harari ,  Ronen Neeman

发明人： Leonid Monassevitch ,  Shlomo Lelcuk ,  Michael Arad ,  Boaz Harari ,  Ronen Neeman

IPC分类号： A61B17/12 ,  A61B17/00 ,  A61B17/064 ,  A61B17/08 ,  A61B17/11 ,  A61B17/122 ,  A61B17/28 ,  A61B17/32 ,  A61B17/10

CPC分类号： A61B17/128 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/0644 ,  A61B17/083 ,  A61B17/11 ,  A61B17/1114 ,  A61B17/1227 ,  A61B17/2812 ,  A61B17/32 ,  A61B2017/00867 ,  A61B2017/0649 ,  A61B2017/1107 ,  A61B2017/1125 ,  A61B2017/1139 ,  A61B2017/1225

摘要： The present invention, discloses an anastomosis clip applicator device for applying a surgical clip, formed at least partly of a shape memory alloy, to press together adjacent wall portions of adjacent hollow organ portions so as to effect anastomosis therebetween. The applicator device includes: gripping apparatus for gripping a surgical clip, a release mechanism, associated with the gripping apparatus, and tissue cutting apparatus, operatively associated with the gripping apparatus. There is also apparatus for activating the gripping apparatus, the release mechanism and the cutting apparatus, so as to introduce and apply the surgical clip into adjacent hollow organ portions, such that the surgical clip compresses together the adjacent walls of the hollow organ portions, and thereafter causes the cutting apparatus to perforate the adjacent pressed together organ walls to provide patency through the joined portions of the hollow organ.

摘要翻译： 本发明公开了一种用于施加至少部分由形状记忆合金形成的手术夹子以将相邻中空器官部分的相邻壁部分压在一起以在其间进行吻合的吻合夹施加器装置。 涂抹器装置包括：与夹持装置可操作地相关联的用于夹持手术夹子的夹持装置，与夹持装置相关联的释放机构和组织切割装置。 还有用于启动夹持装置，释放机构和切割装置的装置，以便将手术夹子引入并应用到相邻的中空器官部分中，使得手术夹子将中空器官部分的相邻壁压缩在一起，以及 然后使切割装置穿过相邻的压制在一起的器官壁，以通过中空器官的连接部分提供通畅。