公开(公告)号：US20070016240A1

公开(公告)日：2007-01-18

申请号：US11455382

申请日：2006-06-19

申请人： Boris Warnack ,  Judith Hartwig ,  Silke Pschibl ,  Travis Yribarren ,  Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

发明人： Boris Warnack ,  Judith Hartwig ,  Silke Pschibl ,  Travis Yribarren ,  Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

IPC分类号： A61M29/00

CPC分类号： A61M25/104 ,  A61M25/1034 ,  A61M25/1038 ,  A61M2025/1004 ,  A61M2025/1031 ,  A61M2025/1086 ,  A61M2025/1093 ,  B23K2103/42 ,  B23K2103/50 ,  B29C59/165 ,  B29C2791/009 ,  B29L2031/7542 ,  Y10T156/1062

摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.

摘要翻译： 根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。 一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。 然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。 气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。 材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。 此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。 袖子附近的刚性减少，导致导管在弯曲通道中的更好的机动性。

公开(公告)号：US20060287703A1

公开(公告)日：2006-12-21

申请号：US11509346

申请日：2006-08-23

申请人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

发明人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/856 ,  A61F2/954 ,  A61M2025/09125 ,  A61M2025/1015

摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.

摘要翻译： 公开了用于在体内容器中的战略取向和位置处递送和展开径向可扩张的支架的支架输送系统。 递送系统包括适于插入身体容器中的细长柔性管状轴。 支架展开组件包括支撑扩张器装置的远侧过渡部分，所述扩张器装置适于围绕展开组件的纵向轴线从非扩张状态到径向膨胀状态的径向膨胀。 扩张器装置构造成在非扩张状态下以相对于展开组件的预定取向支撑其上的支架。 旋转离合器组件将过渡部分可旋转地安装到管状轴的远侧部分，使得展开组件围绕离合器组件的纵向轴线与管状轴基本上扭转隔离。 这使得支架展开组件能够基本上独立于管状轴线旋转，以便在穿过身体血管的进展期间扩张器装置的战略取向。

公开(公告)号：US20070288081A1

公开(公告)日：2007-12-13

申请号：US11747145

申请日：2007-05-10

申请人： Randolf Oepen ,  Arik Zucker ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey

发明人： Randolf Oepen ,  Arik Zucker ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2002/821 ,  A61F2002/9586

摘要： Disclosed are stent delivery apparatus and methods for moving a balloon catheter carrying a stent through a body vessel without the stent slipping from the balloon are provided. In general, the stent delivery system includes a stent stopper that impedes the stent from slipping from the balloon. The stent stopper is sized to serve as a barrier to the stent as it is carried on the balloon. In a specific embodiment, the stent stopper is formed from a material that encircles the proximal end of the balloon and abuts the proximal end of the stent. The stent stopper material expands with expansion of the balloon and collapses with deflation of the balloon. In some embodiments, the stent stopper material has a thickness that is about equal to or greater than the thickness of the stent so as to form a barrier against the stent and impede the stent from slipping off the proximal end of the balloon.

摘要翻译： 公开了用于移动携带支架的球囊导管通过身体容器而没有支架从气囊滑落的支架输送装置和方法。 通常，支架输送系统包括阻止支架从气囊滑落的支架塞子。 支架止动器的尺寸被设计成当支架承载在气囊上时用作支架的屏障。 在具体实施例中，支架止动器由围绕球囊的近端并邻接支架的近端的材料形成。 支架塞材料随气囊膨胀而膨胀，并伴随气囊的放气而塌陷。 在一些实施例中，支架止动器材料具有大约等于或大于支架厚度的厚度，以便形成抵靠支架的阻挡层并阻止支架从气囊的近端滑落。

公开(公告)号：US20070021685A1

公开(公告)日：2007-01-25

申请号：US11429424

申请日：2006-05-04

申请人： Randolf Oepen ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

发明人： Randolf Oepen ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

IPC分类号： A61M25/00

CPC分类号： A61M25/09 ,  A61M2025/09125 ,  A61M2025/09175 ,  A61M2025/09183

摘要： A guidewire apparatus for a medical device that includes an expandable guidewire section that can be locked in an expanded state. In one use, the expandable section can be temporarily locked to a working element of a medical device to facilitate the transmission of torque from the guidewire to the medical device. Hence, this configuration may be utilized to aid in orientation of the working element with a vessel side branch by providing the user with the ability to apply a rotational force to the distal end of the stent delivery system. Another use includes docking the expandable section near an opening into a guidewire lumen at the catheter tip. This configuration is particularly useful in forming a smooth transition between the guidewire and the catheter tip to reduce the phenomenon of fish-mouthing.

摘要翻译： 一种用于医疗装置的导丝装置，其包括能够被锁定在展开状态的可扩张导丝部分。 在一种用途中，可扩张部分可以临时锁定到医疗装置的工作元件，以便于将扭矩从导丝传递到医疗装置。 因此，这种构造可以用于通过向使用者提供向支架输送系统的远端施加旋转力的能力来帮助工作元件与血管侧分支的取向。 另一种用途包括将开口附近的可扩张部分对接在导管尖端处的导丝管腔中。 这种构造在形成导丝和导管尖端之间的平滑过渡以减少鱼嘴的现象特别有用。

公开(公告)号：US20060282154A1

公开(公告)日：2006-12-14

申请号：US11441388

申请日：2006-05-24

申请人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

发明人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/856 ,  A61F2/954 ,  A61M2025/09125 ,  A61M2025/1015

摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.

公开(公告)号：US20070016241A1

公开(公告)日：2007-01-18

申请号：US11474111

申请日：2006-06-23

申请人： Randolf von Oepen ,  Lorcan Coffey ,  Thomas Rieth ,  Travis Yribarren ,  Arik Zucker

发明人： Randolf von Oepen ,  Lorcan Coffey ,  Thomas Rieth ,  Travis Yribarren ,  Arik Zucker

IPC分类号： A61M29/00

CPC分类号： A61M25/10 ,  A61F2/958 ,  A61M25/1002 ,  A61M25/1011 ,  A61M25/1027 ,  A61M25/1029 ,  A61M25/104 ,  A61M2025/018 ,  A61M2025/0183 ,  A61M2025/1045 ,  A61M2025/1056 ,  A61M2025/107 ,  A61M2029/025

摘要： A catheter arrangement is described that is arranged to permit a guide wire or other structure to be fed laterally from the region of an expandable working element. The catheter includes an elongate flexible tubular member and an inflatable structure carried by a distal portion of the flexible tubular member. The flexible tubular member has a guide wire lumen and at least one fluid supply lumen that is in fluid communication with the inflatable structure. The inflatable structure includes at least one, and preferably two, inflatable members (which may take the form of balloons). In the case of two inflatable members, the first and second inflatable members are radially spaced about the guide wire lumen such that at least one gap is formed between the inflatable members. With this arrangement, the distal end of a guide wire may be advanced through the guide lumen and out of a side opening such that the guide wire passes laterally between the first and second inflatable members. With such an arrangement, a guide wire passing out of the side opening in the region between the inflatable members can readily be directed into a second branch of a vessel bifurcation while the device is positioned in a first branch.

摘要翻译： 描述了布置成允许导丝或其他结构从可扩张工作元件的区域横向地供给的导管装置。 导管包括细长的柔性管状构件和由柔性管状构件的远侧部分承载的可膨胀结构。 柔性管状构件具有导丝腔和与可充气结构流体连通的至少一个流体供应腔。 可膨胀结构包括至少一个，优选两个可膨胀构件（其可以采取气球的形式）。 在两个可膨胀构件的情况下，第一和第二可膨胀构件围绕导丝管腔​​径向隔开，使得在可膨胀构件之间形成至少一个间隙。 通过这种布置，导丝的远端可以通过引导腔前进并且从侧开口排出，使得导丝横向地在第一和第二可膨胀构件之间通过。 通过这样的布置，在可膨胀构件之间的区域中的侧开口中的引导线可以容易地被引导到容器分叉的第二分支中，同时装置位于第一分支中。

公开(公告)号：US20070260224A1

公开(公告)日：2007-11-08

申请号：US11683997

申请日：2007-03-08

申请人： Randolf Von Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Richard Newhauser ,  Travis Yribarren

发明人： Randolf Von Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Richard Newhauser ,  Travis Yribarren

IPC分类号： A61M25/16

CPC分类号： A61M25/0054 ,  A61M25/0053 ,  A61M25/0067 ,  A61M25/0069 ,  A61M25/008 ,  A61M25/0138 ,  A61M2025/1093

摘要： A catheter tip for attachment with an intravascular balloon catheter that is used within a body lumen is disclosed. The catheter tip includes a body portion having a base that is attached to the balloon catheter. The base defines a proximal end of the catheter tip. A head that is attached to the body portion defines a distal end of the catheter tip. An axial cavity, cooperatively defined by the body portion and the head, extends longitudinally from the proximal to the distal end of the catheter tip. The axial cavity receives a first guidewire along which the catheter is moved within the body lumen. An outer surface of the head is shaped in a predetermined manner to control the magnitude of deflection of a second guidewire that is often twisted about the first guidewire in the lumen so as to prevent catheter obstruction by the guidewires during catheter procedures.

摘要翻译： 公开了用于与在体腔内使用的血管内气囊导管连接的导管末端。 导管尖端包括具有附接到气囊导管的基部的主体部分。 基部限定了导管尖端的近端。 附接到主体部分的头限定导管末端的远端。 由主体部分和头部协同地限定的轴向腔从导管末端的近端延伸到远端。 轴向空腔容纳第一导丝，导管沿着该第一导丝在体腔内移动。 头部的外表面以预定的方式成形，以控制通常在内腔中围绕第一导丝扭转的第二导丝的偏转量，以防止在导管过程期间导管阻塞导线。

公开(公告)号：US07993303B2

公开(公告)日：2011-08-09

申请号：US11738384

申请日：2007-04-20

申请人： Randolf Von Oepen ,  Ian J. Clark ,  Lorcan Coffey ,  Thomas Rieth ,  Richard Newhauser ,  Travis Yribarren ,  Marc Gianotti ,  Bernhard Uihlein

发明人： Randolf Von Oepen ,  Ian J. Clark ,  Lorcan Coffey ,  Thomas Rieth ,  Richard Newhauser ,  Travis Yribarren ,  Marc Gianotti ,  Bernhard Uihlein

IPC分类号： A61M29/00

CPC分类号： A61M25/0054 ,  A61M25/0053 ,  A61M2025/0006 ,  A61M2025/0025 ,  A61M2025/0063

摘要： A support catheter that can puncture a heart septum with a guidewire without buckling and that can access difficult to reach arteries such as carotid or renal arteries from the aorta under difficult circumstances is provided. The support catheter comprises a catheter body having a proximal end, a distal end, and an interior wall surface defining a first lumen extending from the proximal end toward the distal end. A second lumen is disposed between the interior wall surface and an outer surface of the catheter body. A plurality of stiffening members is disposed around the second lumen, the plurality of stiffening members being engageable to selectively stiffen the catheter body. In another configuration, the catheter further comprises a second plurality of stiffening members disposed between the first lumen and the second lumen.

摘要翻译： 提供了一种支撑导管，其可以用导线刺穿心脏隔膜而没有屈曲，并且可以在困难的情况下进入难以到达主动脉的颈动脉或肾动脉的动脉。 支撑导管包括具有近端，远端和限定从近端朝向远端延伸的第一内腔的内壁表面的导管主体。 第二管腔设置在内壁表面和导管主体的外表面之间。 多个加强构件设置在第二内腔周围，多个加强构件可接合以选择性地加强导管主体。 在另一种构造中，导管还包括设置在第一腔和第二腔之间的第二多个加强构件。

公开(公告)号：US20080027411A1

公开(公告)日：2008-01-31

申请号：US11739050

申请日：2007-04-23

申请人： Randolf Von Oepen ,  Lorcan Coffey ,  Richard Newhauser ,  Thomas Rieth ,  Travis Yribarren

发明人： Randolf Von Oepen ,  Lorcan Coffey ,  Richard Newhauser ,  Thomas Rieth ,  Travis Yribarren

IPC分类号： A61M25/09

CPC分类号： A61M25/0029 ,  A61M25/0071 ,  A61M25/01 ,  A61M25/0108 ,  A61M2025/0037 ,  A61M2025/0063 ,  A61M2025/018

摘要： This invention describes a guidewire placement device for facilitating the delivery of multiple guidewires to the branches of a tubular system. The invention also includes a method for placing guidewires in the branches of a tubular system using a device in accordance with the present invention, while mitigating guidewire entanglement. The present invention may be utilized during percutaneous treatment of vascular and non-vascular disease, and in particular to complement the use of balloon angioplasty and the deployment of balloon-expanded or self-expanding stents into a bifurcated vessel system.

摘要翻译： 本发明描述了一种用于便于将多条导线输送到管状系统的分支的导丝放置装置。 本发明还包括一种使用根据本发明的装置将导线布置在管状系统的分支中的方法，同时减轻导丝缠结。 本发明可以在血管和非血管疾病的经皮治疗期间使用，特别是补充使用球囊血管成形术和将球囊扩张或自扩张支架部署到分叉血管系统中。

公开(公告)号：US20070270933A1

公开(公告)日：2007-11-22

申请号：US11683999

申请日：2007-03-08

申请人： Randolf Von Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Richard Newhauser ,  Travis Yribarren

发明人： Randolf Von Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Richard Newhauser ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/856 ,  A61F2/91 ,  A61F2/915 ,  A61F2/954 ,  A61F2/958 ,  A61F2002/821 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91541 ,  A61F2002/91558

摘要： A contoured intraluminal stent for deployment proximate a bifurcated vessel is disclosed. The contoured stent is configured to seat within a side branch of the bifurcated vessel so as to acceptably cover a curvilinear ostium defined at the intersection of the side branch with a main branch of the vessel. A stent deployment system includes a first guidewire positioned in the vessel main branch and a second guidewire that extends through the main branch and into the vessel side branch, wherein the intersection of the branches defines an ostium having a three-dimensionally curvilinear shape. A balloon catheter is tracked along the second guidewire to a position in the side branch proximate the ostium. A contoured stent disposed about the balloon includes a proximal end that defines a curvilinear profile that at least approximately matches the curvilinear shape of the ostium when the stent is deployed in the side branch.

摘要翻译： 公开了一种用于在分叉血管附近部署的成型的管腔内支架。 轮廓支架被配置为位于分叉血管的侧分支内，以便可接受地覆盖在侧分支与血管的主分支的交叉处限定的曲线口。 支架展开系统包括位于容器主分支中的第一导丝和延伸穿过主分支并进入血管侧分支的第二导线，其中分支的交点限定具有三维曲线形状的口。 气球导管沿着第二导丝被跟踪到靠近口的侧分支中的位置。 围绕气囊设置的成像支架包括限定曲线轮廓的近端，当支架部署在侧支中时，该近端至少近似匹配口的曲线形状。