公开(公告)号：US20070016240A1

公开(公告)日：2007-01-18

申请号：US11455382

申请日：2006-06-19

申请人： Boris Warnack ,  Judith Hartwig ,  Silke Pschibl ,  Travis Yribarren ,  Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

发明人： Boris Warnack ,  Judith Hartwig ,  Silke Pschibl ,  Travis Yribarren ,  Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

IPC分类号： A61M29/00

CPC分类号： A61M25/104 ,  A61M25/1034 ,  A61M25/1038 ,  A61M2025/1004 ,  A61M2025/1031 ,  A61M2025/1086 ,  A61M2025/1093 ,  B23K2103/42 ,  B23K2103/50 ,  B29C59/165 ,  B29C2791/009 ,  B29L2031/7542 ,  Y10T156/1062

摘要： A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways.

摘要翻译： 根据在球囊和/或导管部分中形成空腔和凹陷的方法制造扩张球囊。 一段长度的管材是轴向伸长的并以一种形式径向扩张以提供必要的双轴取向和强度。 然后，使用准分子激光器或其他类型的激光或机械材料去除工具来去除聚合物材料，实际上没有热效应。 气囊的套筒部分中的腔被限定，并且如果需要，限定锥形部分中的凹陷。 材料去除，特别是靠近气球套筒，能够在导管轴和球囊之间形成更薄，更灵活的粘结区域。 此外，沿着锥形部分的凹陷使得气囊能够更紧密地包裹以减少输送轮廓。 袖子附近的刚性减少，导致导管在弯曲通道中的更好的机动性。

公开(公告)号：US20060287703A1

公开(公告)日：2006-12-21

申请号：US11509346

申请日：2006-08-23

申请人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

发明人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/856 ,  A61F2/954 ,  A61M2025/09125 ,  A61M2025/1015

摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.

摘要翻译： 公开了用于在体内容器中的战略取向和位置处递送和展开径向可扩张的支架的支架输送系统。 递送系统包括适于插入身体容器中的细长柔性管状轴。 支架展开组件包括支撑扩张器装置的远侧过渡部分，所述扩张器装置适于围绕展开组件的纵向轴线从非扩张状态到径向膨胀状态的径向膨胀。 扩张器装置构造成在非扩张状态下以相对于展开组件的预定取向支撑其上的支架。 旋转离合器组件将过渡部分可旋转地安装到管状轴的远侧部分，使得展开组件围绕离合器组件的纵向轴线与管状轴基本上扭转隔离。 这使得支架展开组件能够基本上独立于管状轴线旋转，以便在穿过身体血管的进展期间扩张器装置的战略取向。

公开(公告)号：US20070288081A1

公开(公告)日：2007-12-13

申请号：US11747145

申请日：2007-05-10

申请人： Randolf Oepen ,  Arik Zucker ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey

发明人： Randolf Oepen ,  Arik Zucker ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2002/821 ,  A61F2002/9586

摘要： Disclosed are stent delivery apparatus and methods for moving a balloon catheter carrying a stent through a body vessel without the stent slipping from the balloon are provided. In general, the stent delivery system includes a stent stopper that impedes the stent from slipping from the balloon. The stent stopper is sized to serve as a barrier to the stent as it is carried on the balloon. In a specific embodiment, the stent stopper is formed from a material that encircles the proximal end of the balloon and abuts the proximal end of the stent. The stent stopper material expands with expansion of the balloon and collapses with deflation of the balloon. In some embodiments, the stent stopper material has a thickness that is about equal to or greater than the thickness of the stent so as to form a barrier against the stent and impede the stent from slipping off the proximal end of the balloon.

摘要翻译： 公开了用于移动携带支架的球囊导管通过身体容器而没有支架从气囊滑落的支架输送装置和方法。 通常，支架输送系统包括阻止支架从气囊滑落的支架塞子。 支架止动器的尺寸被设计成当支架承载在气囊上时用作支架的屏障。 在具体实施例中，支架止动器由围绕球囊的近端并邻接支架的近端的材料形成。 支架塞材料随气囊膨胀而膨胀，并伴随气囊的放气而塌陷。 在一些实施例中，支架止动器材料具有大约等于或大于支架厚度的厚度，以便形成抵靠支架的阻挡层并阻止支架从气囊的近端滑落。

公开(公告)号：US20070021685A1

公开(公告)日：2007-01-25

申请号：US11429424

申请日：2006-05-04

申请人： Randolf Oepen ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

发明人： Randolf Oepen ,  Travis Yribarren ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker

IPC分类号： A61M25/00

CPC分类号： A61M25/09 ,  A61M2025/09125 ,  A61M2025/09175 ,  A61M2025/09183

摘要： A guidewire apparatus for a medical device that includes an expandable guidewire section that can be locked in an expanded state. In one use, the expandable section can be temporarily locked to a working element of a medical device to facilitate the transmission of torque from the guidewire to the medical device. Hence, this configuration may be utilized to aid in orientation of the working element with a vessel side branch by providing the user with the ability to apply a rotational force to the distal end of the stent delivery system. Another use includes docking the expandable section near an opening into a guidewire lumen at the catheter tip. This configuration is particularly useful in forming a smooth transition between the guidewire and the catheter tip to reduce the phenomenon of fish-mouthing.

摘要翻译： 一种用于医疗装置的导丝装置，其包括能够被锁定在展开状态的可扩张导丝部分。 在一种用途中，可扩张部分可以临时锁定到医疗装置的工作元件，以便于将扭矩从导丝传递到医疗装置。 因此，这种构造可以用于通过向使用者提供向支架输送系统的远端施加旋转力的能力来帮助工作元件与血管侧分支的取向。 另一种用途包括将开口附近的可扩张部分对接在导管尖端处的导丝管腔中。 这种构造在形成导丝和导管尖端之间的平滑过渡以减少鱼嘴的现象特别有用。

公开(公告)号：US20060282154A1

公开(公告)日：2006-12-14

申请号：US11441388

申请日：2006-05-24

申请人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

发明人： Randolf Oepen ,  Thomas Rieth ,  Lorcan Coffey ,  Arik Zucker ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/958 ,  A61F2/856 ,  A61F2/954 ,  A61M2025/09125 ,  A61M2025/1015

摘要： A stent delivery system is disclosed for delivering and deploying a radially expandable stent at a strategic orientation and location in a body vessel. The delivery system includes an elongated flexible tubular shaft sized suitably for insertion into the body vessel. A stent deployment assembly includes a distal transition portion supporting a dilator device adapted for radial expansion about a longitudinal axis of the deployment assembly from a non-expanded condition to a radially expanded condition. The dilator device is configured to support the stent thereon in the non-expanded condition and in predetermined orientation relative the deployment assembly. A rotational clutch assembly rotatably mounts the transition portion to a distal portion of the tubular shaft such that the deployment assembly is substantially torsionally isolated from the tubular shaft, about a longitudinal axis of the clutch assembly. This enables the stent deployment assembly to rotate substantially independently of the tubular shaft for strategic orientation of the dilator device during advancement through the body vessel.

公开(公告)号：US20070016132A1

公开(公告)日：2007-01-18

申请号：US11439591

申请日：2006-05-23

申请人： Randolf Oepen ,  Axel Grandt ,  Lorcan Coffey ,  Louise Balfe ,  Andrew Jeffrey ,  Ib Joergensen ,  Bodo Quint

发明人： Randolf Oepen ,  Axel Grandt ,  Lorcan Coffey ,  Louise Balfe ,  Andrew Jeffrey ,  Ib Joergensen ,  Bodo Quint

IPC分类号： A61M29/00

CPC分类号： A61M25/10 ,  A61M2025/0063 ,  A61M2025/0183

摘要： The invention includes a catheter having an elongate main body having a proximal section and a distal section. The elongate main body further includes a plurality of stiffening members disposed along the length of the elongate main body. At least one stiffening member includes a plurality of clusters including helical turns or rotations disposed circumferentially about a tubular member and along the length of the cluster. The clusters can be configured to vary flexibility along the length of the tubular member. The catheter can include a sheath having a stationary section and a retractable section.

摘要翻译： 本发明包括具有细长主体的导管，该主体具有近端部分和远端部分。 细长主体还包括沿着细长主体的长度设置的多个加强构件。 至少一个加强构件包括多个簇，包括围绕管状构件并沿着簇的长度周向设置的螺旋形匝或旋转。 簇可以被配置为沿着管状构件的长度改变柔性。 导管可以包括具有固定部分和可缩回部分的护套。

公开(公告)号：US20070255094A1

公开(公告)日：2007-11-01

申请号：US11375380

申请日：2006-03-13

申请人： Randolf Oepen ,  Travis Yribarren ,  Anton Clifford

发明人： Randolf Oepen ,  Travis Yribarren ,  Anton Clifford

IPC分类号： A61B1/00

CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/3008 ,  A61F2002/30329 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2220/0025 ,  A61F2230/0054 ,  A61F2240/001 ,  A61F2250/0068 ,  A61F2250/0098

摘要： An endoprosthesis for delivery in a body lumen can be configured to inhibit crack formation and/or crack propagation, and/or fatigue-induced catastrophic failure by the use of holes extending through an endoprosthetic element. As such, the endoprosthesis can include at least one strut element having a strut width and a strut thickness, the strut thickness being defined by a first side opposite a second side. The element can be characterized by having a plurality of holes extending from the first side to the second side. The plurality of holes can be arranged in an amount, distribution, and/or pattern so as to inhibit crack propagation across the strut length or strut width.

摘要翻译： 用于在体腔内递送的内用假体可以被配置为通过使用延伸穿过假体内元件的孔来抑制裂缝形成和/或裂纹扩展，和/或疲劳引起的灾难性故障。 因此，内假体可以包括至少一个支柱元件，支柱宽度和支柱厚度，支柱厚度由与第二侧相对的第一侧限定。 元件的特征在于具有从第一侧延伸到第二侧的多个孔。 可以以数量，分布和/或图案布置多个孔，以便抑制穿过支柱长度或支柱宽度的裂纹扩展。

公开(公告)号：US20060235505A1

公开(公告)日：2006-10-19

申请号：US11375381

申请日：2006-03-13

申请人： Randolf Oepen ,  Anton Clifford ,  Travis Yribarren

发明人： Randolf Oepen ,  Anton Clifford ,  Travis Yribarren

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61F2/0077 ,  A61F2/90 ,  A61F2/915 ,  A61F2002/3008 ,  A61F2002/30329 ,  A61F2002/828 ,  A61F2002/91508 ,  A61F2002/91533 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/91583 ,  A61F2210/0076 ,  A61F2220/0025 ,  A61F2230/0054 ,  A61F2240/001 ,  A61F2250/0068 ,  A61F2250/0098

摘要： A crack-resistant endoprosthesis for delivery in a body lumen can be comprised of a multilayered material. The multilayered material can include at least two layers having a boundary layer therebetween. The boundary layer is configured to inhibit cracks from propagating from a first layer-to a second layer. The different layers can be comprised of the same materials or different materials. It can be preferred that the multilayered material have layers that are comprised of resiliently-flexible materials, shape memory materials, and/or radiopaque materials.

摘要翻译： 用于在体腔中输送的抗裂内固定物可以由多层材料构成。 多层材料可以包括其间具有边界层的至少两层。 边界层被配置为抑制裂纹从第一层传播到第二层。 不同的层可以由相同的材料或不同的材料组成。 可以优选的是，多层材料具有由弹性柔性材料，形状记忆材料和/或不透射线材料构成的层。

公开(公告)号：US20070083188A1

公开(公告)日：2007-04-12

申请号：US11357775

申请日：2006-02-17

申请人： Axel Grandt ,  Randolf Oepen ,  Thomas Rieth

发明人： Axel Grandt ,  Randolf Oepen ,  Thomas Rieth

IPC分类号： A61M25/00

CPC分类号： A61M25/10 ,  A61M2025/0063 ,  A61M2025/0183

摘要： Catheter including an elongate main body having a proximal section and a distal section. The elongate main body further includes a guidewire lumen along at least a portion of the elongate main body. In accordance with a further aspect of the invention, the catheter includes a first stiffening member and a second stiffening in an overlapping spaced relationship along at least a portion of a length between the distal end and the proximal end of the elongate main body.

摘要翻译： 导管包括具有近端部分和远端部分的细长主体。 细长主体还包括沿细长主体的至少一部分的导丝内腔。 根据本发明的另一方面，导管包括第一加强构件和沿着细长主体的远端和近端之间的长度的至少一部分上的重叠间隔关系的第二加强件。

公开(公告)号：US20050267408A1

公开(公告)日：2005-12-01

申请号：US11136640

申请日：2005-05-23

申请人： Axel Grandt ,  Randolf Oepen ,  Thomas Rieth

发明人： Axel Grandt ,  Randolf Oepen ,  Thomas Rieth

IPC分类号： A61F2/958 ,  A61M25/00 ,  A61M29/02 ,  A61M31/00

CPC分类号： A61M25/0021 ,  A61M25/0029 ,  A61M25/0032 ,  A61M25/0043 ,  A61M25/10 ,  A61M2025/0063 ,  A61M2025/0183 ,  A61M2025/1056

摘要： The invention includes a catheter having an elongate main body having a proximal section and a distal section. The elongate main body further includes a first guidewire lumen and a second guidewire lumen. Each guide wire lumen including a proximal port and a distal port in communication with an external environment. The proximal port of the first guidewire lumen spaced by a gap from the distal port of the second guidewire lumen. In accordance with a further aspect of the invention, the catheter includes a plurality of overlapping stiffening members defined along at least a portion of a length between the distal end and the proximal end of the elongate main body.

摘要翻译： 本发明包括具有细长主体的导管，该主体具有近端部分和远端部分。 细长主体还包括第一导丝管腔和第二导丝管腔。 每个导丝管腔包括与外部环境连通的近端口和远端口。 第一导丝管腔的近端口与第二导丝管腔的远端口间隔开间隔开。 根据本发明的另一方面，导管包括沿细长主体的远端和近端之间的长度的至少一部分限定的多个重叠的加强构件。