公开(公告)号：US20250017956A1

公开(公告)日：2025-01-16

申请号：US18762216

申请日：2024-07-02

Applicant: Boston Scientific Scimed, Inc.

Inventor： Yen-Hao Hsu ,  Joseph Thomas Delaney, JR. ,  Rick Dorn ,  Cristian Parisi ,  Niraj Gurung ,  Claire Hobbs

IPC: A61K31/765 ,  A61K45/06 ,  C08J3/075 ,  C08K3/011

Abstract: Disclosed herein are radiopaque, reactive multi-arm polymers that comprise an iodine-containing core region, a plurality of polymer arms comprising a plurality of polymer segments linked to the iodine-containing core region, and a plurality of reactive moieties linked to the plurality of polymer segments. Also disclosed are methods of forming such radiopaque, reactive multi-arm polymers, systems for forming hydrogel compositions that comprise (a) such radiopaque, reactive multi-arm polymers and (b) multifunctional crosslinking compounds comprising a plurality of complementary reactive moieties that are reactive with the reactive moieties of the radiopaque, reactive multi-arm polymers, as well as reaction products of such systems and methods of treatment using such systems.

公开(公告)号：US20180303972A1

公开(公告)日：2018-10-25

申请号：US15959894

申请日：2018-04-23

Applicant: Boston Scientific Scimed, Inc.

Inventor： Joseph Thomas Delaney, JR. ,  Patrick Willoughby ,  David Robert Wulfman ,  Andrew J. Ro ,  Niraj Gurung

IPC: A61L27/16 ,  C08L53/00 ,  C08J3/24

CPC classification number: A61L27/16 ,  A61L27/48 ,  A61L2430/20 ,  C08J3/246 ,  C08J2323/22 ,  C08J2337/00 ,  C08J2479/02 ,  C08L53/00 ,  C08L2203/02 ,  C08L23/22

Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.

公开(公告)号：US12115275B2

公开(公告)日：2024-10-15

申请号：US17179971

申请日：2021-02-19

Applicant: Boston Scientific Scimed, Inc.

Inventor： Joseph Thomas Delaney, Jr. ,  Patrick Willoughby ,  David Robert Wulfman ,  Andrew J. Ro ,  Niraj Gurung

IPC: A61L27/16 ,  A61L27/48 ,  C08J3/24 ,  C08L53/00 ,  D01D5/00 ,  D01D5/098

CPC classification number: A61L27/16 ,  A61L27/48 ,  C08J3/246 ,  C08L53/00 ,  D01D5/0023 ,  D01D5/003 ,  D01D5/0985 ,  A61L2430/20 ,  C08J2323/18 ,  C08J2323/22 ,  C08J2337/00 ,  C08J2479/02 ,  C08L2203/02 ,  D10B2509/06 ,  A61L27/48 ,  C08L23/22

Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.

公开(公告)号：US20210170069A1

公开(公告)日：2021-06-10

申请号：US17179971

申请日：2021-02-19

Applicant: Boston Scientific Scimed, Inc.

Inventor： Joseph Thomas Delaney, JR. ,  Patrick Willoughby ,  David Robert Wulfman ,  Andrew J. Ro ,  Niraj Gurung

IPC: A61L27/16 ,  D01D5/098 ,  A61L27/48 ,  C08L53/00 ,  D01D5/00 ,  C08J3/24

Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.

公开(公告)号：US10925998B2

公开(公告)日：2021-02-23

申请号：US15959894

申请日：2018-04-23

Applicant: Boston Scientific Scimed, Inc.

Inventor： Joseph Thomas Delaney, Jr. ,  Patrick Willoughby ,  David Robert Wulfman ,  Andrew J. Ro ,  Niraj Gurung

IPC: C08J3/24 ,  C08J7/04 ,  C08J7/056 ,  C08L23/18 ,  C08L23/22 ,  D01D5/08 ,  D01D5/18 ,  D02G3/36 ,  A61L27/16 ,  C08L53/00 ,  A61L27/48 ,  D01D5/00 ,  D01D5/098

Abstract: Aspects herein relate to biocompatible polyisobutylene-fiber composite materials and related methods. In one aspect a biocompatible composite material is included. The biocompatible composite material can include a network of fibers comprising one or more polymers to form a substrate and a continuous, interpenetrating polyisobutylene matrix that is non-porous and completely surrounds the electrospun fibers. Other aspects are included herein.