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公开(公告)号:US20110230741A1
公开(公告)日:2011-09-22
申请号:US13151601
申请日:2011-06-02
申请人: Bradley Chi Liang , Larry E. Tyler , Mohsen Askarinya , Charles Robert Gordon , Randal C. Schulhauser , Kenneth W. Cooper , Kris R. Holtzclaw , Brian T. Kannard , Rajiv Shah
发明人: Bradley Chi Liang , Larry E. Tyler , Mohsen Askarinya , Charles Robert Gordon , Randal C. Schulhauser , Kenneth W. Cooper , Kris R. Holtzclaw , Brian T. Kannard , Rajiv Shah
IPC分类号: A61B5/1473 , G06F19/00 , G01R27/08
CPC分类号: A61B5/14532 , A61B5/14865
摘要: The invention disclosed herein provides methods and materials for observing the state of a sensor, for example those used by diabetic patients to monitor blood glucose levels. Typically a voltage such as a voltage pulse is applied to the sensor in order to solicit a current response from which for example, factors such as impedance values can be derived. Such values can then be used as indicators of a sensor's state, for example the state of sensor hydration, sensor noise, sensor offset, sensor drift or the like.
摘要翻译: 本文公开的本发明提供了用于观察传感器状态的方法和材料,例如糖尿病患者用于监测血糖水平的传感器的状态。 通常,诸如电压脉冲的电压被施加到传感器,以便征求电流响应,例如可以导出诸如阻抗值的因素。 然后可以将这些值用作传感器状态的指示器,例如传感器水合状态,传感器噪声,传感器偏移,传感器漂移等。
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公开(公告)号:US20100169035A1
公开(公告)日:2010-07-01
申请号:US12345354
申请日:2008-12-29
申请人: Bradley Chi Liang , Larry E. Tyler , Mohsen Askarinya , Charles Robert Gordon , Randal C. Schulhauser , Kenneth W. Cooper , Kris R. Holtzclaw , Brian T. Kannard , Rajiv Shah
发明人: Bradley Chi Liang , Larry E. Tyler , Mohsen Askarinya , Charles Robert Gordon , Randal C. Schulhauser , Kenneth W. Cooper , Kris R. Holtzclaw , Brian T. Kannard , Rajiv Shah
CPC分类号: A61B5/14532 , A61B5/14865
摘要: The invention disclosed herein provides methods and materials for observing the state of a sensor, for example those used by diabetic patients to monitor blood glucose levels. Typically a voltage such as a voltage pulse is applied to the sensor in order to solicit a current response from which for example, factors such as impedance values can be derived. Such values can then be used as indicators of a sensor's state, for example the state of sensor hydration, sensor noise, sensor offset, sensor drift or the like.
摘要翻译: 本文公开的本发明提供了用于观察传感器状态的方法和材料,例如糖尿病患者用于监测血糖水平的传感器的状态。 通常,诸如电压脉冲的电压被施加到传感器,以便征求电流响应,例如可以导出诸如阻抗值的因素。 然后可以将这些值用作传感器状态的指示器,例如传感器水合状态,传感器噪声,传感器偏移,传感器漂移等。
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公开(公告)号:US08160834B2
公开(公告)日:2012-04-17
申请号:US13151601
申请日:2011-06-02
申请人: Bradley Chi Liang , Larry E. Tyler , Mohsen Askarinya , Charles R. Gordon , Randal C. Schulhauser , Kenneth W. Cooper , Kris R. Holtzclaw , Brian T. Kannard , Rajiv Shah
发明人: Bradley Chi Liang , Larry E. Tyler , Mohsen Askarinya , Charles R. Gordon , Randal C. Schulhauser , Kenneth W. Cooper , Kris R. Holtzclaw , Brian T. Kannard , Rajiv Shah
CPC分类号: A61B5/14532 , A61B5/14865
摘要: The invention disclosed herein provides methods and materials for observing the state of a sensor, for example those used by diabetic patients to monitor blood glucose levels. Typically a voltage such as a voltage pulse is applied to the sensor in order to solicit a current response from which for example, factors such as impedance values can be derived. Such values can then be used as indicators of a sensor's state, for example the state of sensor hydration, sensor noise, sensor offset, sensor drift or the like.
摘要翻译: 本文公开的本发明提供了用于观察传感器状态的方法和材料,例如糖尿病患者用于监测血糖水平的传感器的状态。 通常,诸如电压脉冲的电压被施加到传感器,以便征求电流响应,例如可以导出诸如阻抗值的因素。 然后可以将这些值用作传感器状态的指示器,例如传感器水合状态,传感器噪声,传感器偏移,传感器漂移等。
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公开(公告)号:US08550997B2
公开(公告)日:2013-10-08
申请号:US12651213
申请日:2009-12-31
申请人: Cary Talbot , Kris R. Holtzclaw , Hans K. Wenstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
发明人: Cary Talbot , Kris R. Holtzclaw , Hans K. Wenstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
CPC分类号: A61B5/14532 , A61B5/14514 , A61B2560/0209 , A61B2560/0276 , A61B2560/0412 , A61B2560/0443 , A61B2560/0456
摘要: A monitor system is disclosed. The monitor system includes a sensor with a sensor port. The monitor system further includes a recorder with a recorder port within a recording housing. The recorder port interfaces with the sensor port to receive signals from the sensor port. A recorder clock is defined within the recorder housing, with a recorder processor to store signals from the sensor. The recorder includes a data port to interface with a dock receiver. The monitor system includes a dock remotely located from the sensor and the recorder. The dock receiver couples the recorder to the dock. The monitor system further includes a data processor to analyze the sensor signals from the recorder. The data processor includes memory and a clock. Further included with the data processor are program instructions to assign the time and date of the sensor signals.
摘要翻译: 公开了一种监视器系统。 监视器系统包括一个带传感器端口的传感器。 监视器系统还包括具有在记录外壳内的记录器端口的记录器。 记录器端口与传感器端口连接,以从传感器端口接收信号。 记录器时钟被定义在记录器外壳内,记录器处理器存储来自传感器的信号。 记录器包括与坞站接收器接口的数据端口。 监视器系统包括远离传感器和记录器的基座。 码头接收器将录音机连接到码头。 监视器系统还包括数据处理器,用于分析来自记录器的传感器信号。 数据处理器包括存储器和时钟。 数据处理器还包括用于分配传感器信号的时间和日期的程序指令。
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公开(公告)号:US20110160553A1
公开(公告)日:2011-06-30
申请号:US12651213
申请日:2009-12-31
申请人: Cary Talbot , Kris R. Holtzclaw , Hans K. Wanstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
发明人: Cary Talbot , Kris R. Holtzclaw , Hans K. Wanstad , Gary Cohen , Brian T. Kannard , Keith E. DeBrunner , Joseph Makram Arsanious , Fan Meng , Andrew Michael Bryan , Ulrich H. Rankers
IPC分类号: A61B5/145
CPC分类号: A61B5/14532 , A61B5/14514 , A61B2560/0209 , A61B2560/0276 , A61B2560/0412 , A61B2560/0443 , A61B2560/0456
摘要: A monitor system to monitor a characteristic of a user is disclosed. The monitor system includes a sensor to produce a signal indicative of a glucose characteristic measured in the user, the sensor further having a sensor port. The monitor system further includes a recorder within a recording housing, the recorder hosing also encompassing a batter. The recorder further includes a recorder port that interfaces with the sensor port in order to receive the produced signals from the sensor port. A recorder clock that assigns a time to the signals from the sensor is also defined within the recorder housing, as is a recorder processor that includes a recorder memory that is coupled to the recorder port to store the produced signals from the sensor. The recorder further includes a data port defined to interface with a dock receiver. A dock that is remotely located from the sensor and the recorder is also included with the monitor system. The dock includes the dock receiver that physically couples the recorder to the dock via the data port and a dock processor that is coupled to the dock receiver. The monitor system further includes a data processor defined to analyze the signals from the sensor that were stored in the recorder. The data processor includes: a data processor memory to store data from the recorder and a data processor clock. Further included with the data processor is a program to assign the time and date of the signals from the sensor by comparing the time and date on the data processor clock with the time assigned to the signals from the sensor by the recorder clock.
摘要翻译: 公开了一种用于监视用户特性的监视器系统。 监视器系统包括传感器,用于产生指示在用户中测量的葡萄糖特性的信号,该传感器还具有传感器端口。 监视器系统还包括在记录外壳内的记录器,记录器还包括面糊。 记录器还包括与传感器端口接口以便从传感器端口接收所产生的信号的记录器端口。 在记录器外壳内也定义了一个将时间分配给传感器的信号的记录器时钟,记录器处理器还包括与记录器端口相连的记录器存储器,以存储来自传感器的信号。 记录器还包括被定义为与码头接收器接口的数据端口。 远程位于传感器和记录仪的底座也包含在监视器系统中。 码头包括通过数据端口将记录器物理耦合到坞站的坞站接收器和耦合到坞站接收器的坞站处理器。 监视器系统还包括定义为分析存储在记录器中的来自传感器的信号的数据处理器。 数据处理器包括:数据处理器存储器,用于存储来自记录器的数据和数据处理器时钟。 数据处理器还包括一个程序,通过将数据处理器时钟上的时间和日期与分配给传感器的信号的时间与记录器时钟进行比较,来分配来自传感器的信号的时间和日期。
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公开(公告)号:US07029444B2
公开(公告)日:2006-04-18
申请号:US10926319
申请日:2004-08-25
申请人: John J. Shin , Kris R. Holtzclaw , Nandita D. Dangui , Sami Kanderian, Jr. , John J. Mastrototaro , Peter I. Hong
发明人: John J. Shin , Kris R. Holtzclaw , Nandita D. Dangui , Sami Kanderian, Jr. , John J. Mastrototaro , Peter I. Hong
IPC分类号: A61B5/00
CPC分类号: A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/6848 , A61B5/6849 , A61M2005/1726 , G06F19/00
摘要: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression. Alternatively, the calculation of the calibration characteristics is obtained using non-linear regression.
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公开(公告)号:US20080300572A1
公开(公告)日:2008-12-04
申请号:US11757153
申请日:2007-06-01
申请人: Ulrich Rankers , Bradley J. Enegren , Rebecca K. Gottlieb , Jino Han , Kris R. Holtzclaw , Peter I. Hong , Emilian Istoc , John J. Mastrototaro , Sheldon B. Moberg , Cary Talbot , Gary L. Williams , Arieh S. Halpern
发明人: Ulrich Rankers , Bradley J. Enegren , Rebecca K. Gottlieb , Jino Han , Kris R. Holtzclaw , Peter I. Hong , Emilian Istoc , John J. Mastrototaro , Sheldon B. Moberg , Cary Talbot , Gary L. Williams , Arieh S. Halpern
IPC分类号: A61M37/00
CPC分类号: A61B5/4839 , A61B5/14532 , A61B5/411 , A61B5/7275 , A61M5/142 , A61M5/14244 , A61M5/172 , A61M2205/18 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2205/505 , A61M2209/01 , G06F19/3418 , G06F19/3468 , G16H40/63
摘要: A monitor device for a fluid infusion system and its operating, display, and data processing characteristics are described herein. One embodiment of the monitor device is used in an insulin infusion system having an insulin infusion pump and a continuous glucose sensor transmitter. The monitor device is configured as a wireless bedside monitor that wirelessly receives status data from a device in the fluid infusion system, such as the infusion pump or the sensor transmitter. The monitor device supports a number of user interface features, alarm/alert features, and graphical display features, where such features enhance the overall operation and user-friendliness of the monitor device. For example, the monitor device can generate status icons that graphically indicate the time remaining for an exhaustible operating quantity of a device in the infusion system (e.g., a battery charge, a fluid reservoir volume, or a calibration or replacement period). The monitor device can also estimate future measurements of a physiological characteristic of a monitored patient, based upon empirical measurement data received by the monitor device.
摘要翻译: 本文描述了用于流体输注系统的监视器装置及其操作,显示和数据处理特性。 监测装置的一个实施例用于具有胰岛素输注泵和连续葡萄糖传感器发射器的胰岛素输注系统中。 监视器装置被配置为无线床边监视器,其从诸如输液泵或传感器发射器的流体输注系统中的装置无线地接收状态数据。 监视器设备支持许多用户界面功能,警报/警报功能和图形显示功能,其中这些功能可提高监视器设备的整体操作和用户友好性。 例如,监视器设备可以生成状态图标,其图形地指示输注系统中的设备的可耗费的操作量的剩余时间(例如,电池充电,流体存储器容积,或校准或更换周期)。 监视器装置还可以基于由监视器装置接收的经验测量数据来估计被监视患者的生理特征的未来测量。
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公开(公告)号:US20070255348A1
公开(公告)日:2007-11-01
申请号:US11583344
申请日:2006-10-18
申请人: Kris R. Holtzclaw
发明人: Kris R. Holtzclaw
IPC分类号: A61N1/00
CPC分类号: A61B5/0002 , A61B5/14532 , A61B5/4839 , A61B2560/045 , A61M5/1723 , A61M2205/3561 , A61M2205/3592 , A61M2205/52 , A61M2230/201 , G06F19/3468 , H04L67/12 , H04L67/125 , H04L67/28
摘要: A fluid infusion system as described herein includes a number of local “body network” devices, such as an infusion pump, a handheld monitor or controller, a physiological sensor, and a bedside or hospital monitor. The body network devices can be configured to support communication of status data, physiological information, alerts, control signals, and other information between one another. In addition, the body network devices can be configured to support networked communication of status data, physiological information, alerts, control signals, and other information between the body network devices and “external” devices, systems, or communication networks. Such external communication allows the infusion system to be extended beyond the traditional short-range user environment. One particular system embodiment includes a network router device that functions as a centralized storage, processing, and routing unit for data received from the body network devices. The network router device is configured to generate HTML documents (web pages) to facilitate Internet-based setup, management, and control.
摘要翻译: 如本文所述的流体输注系统包括许多局部“身体网络”装置,例如输液泵,手持式监视器或控制器,生理传感器和床边或医院监护仪。 身体网络设备可以被配置为支持状态数据,生理信息,警报,控制信号和彼此之间的其他信息的通信。 此外,身体网络设备可以被配置为支持身体网络设备和“外部”设备,系统或通信网络之间的状态数据,生理信息,警报,控制信号和其他信息的网络通信。 这种外部通信允许输注系统延伸到传统的短距离用户环境之外。 一个特定系统实施例包括网络路由器设备,其用作用于从身体网络设备接收的数据的集中式存储,处理和路由单元。 网络路由器设备被配置为生成HTML文档(网页),以促进基于Internet的设置,管理和控制。
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公开(公告)号:US06895263B2
公开(公告)日:2005-05-17
申请号:US10141375
申请日:2002-05-08
申请人: John J. Shin , Kris R. Holtzclaw , Nandita D. Dangui , Sami Kanderian, Jr. , John J. Mastrototaro , Peter I. Hong
发明人: John J. Shin , Kris R. Holtzclaw , Nandita D. Dangui , Sami Kanderian, Jr. , John J. Mastrototaro , Peter I. Hong
IPC分类号: G01N33/66 , A61B5/00 , A61B5/145 , A61B5/1468 , A61B5/1486 , A61B5/1495
CPC分类号: A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/6848 , A61B5/6849 , A61M2005/1726 , G06F19/00
摘要: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression. Alternatively, the calculation of the calibration characteristics is obtained using non-linear regression.
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公开(公告)号:US20100010330A1
公开(公告)日:2010-01-14
申请号:US12564830
申请日:2009-09-22
申请人: Ulrich Rankers , Bradley J. Enegren , Rebecca K. Gottlieb , Jino Han , Kris R. Holtzclaw , Peter I. Hong , Emilian Istoc , John J. Mastrototaro , Sheldon B. Moberg , Cary Talbot , Gary L. Williams , Arieh S. Halpern
发明人: Ulrich Rankers , Bradley J. Enegren , Rebecca K. Gottlieb , Jino Han , Kris R. Holtzclaw , Peter I. Hong , Emilian Istoc , John J. Mastrototaro , Sheldon B. Moberg , Cary Talbot , Gary L. Williams , Arieh S. Halpern
IPC分类号: A61B5/145
CPC分类号: A61B5/4839 , A61B5/14532 , A61B5/411 , A61B5/7275 , A61M5/142 , A61M5/14244 , A61M5/172 , A61M2205/18 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2205/505 , A61M2209/01 , G06F19/3418 , G06F19/3468 , G16H40/63
摘要: A monitor device for a fluid infusion system and its operating, display, and data processing characteristics are described herein. One embodiment of the monitor device is used in an insulin infusion system having an insulin infusion pump and a continuous glucose sensor transmitter. The monitor device is configured as a wireless bedside monitor that wirelessly receives status data from a device in the fluid infusion system, such as the infusion pump or the sensor transmitter. The monitor device supports a number of user interface features, alarm/alert features, and graphical display features, where such features enhance the overall operation and user-friendliness of the monitor device. For example, the monitor device can generate status icons that graphically indicate the time remaining for an exhaustible operating quantity of a device in the infusion system (e.g., a battery charge, a fluid reservoir volume, or a calibration or replacement period). The monitor device can also estimate future measurements of a physiological characteristic of a monitored patient, based upon empirical measurement data received by the monitor device.
摘要翻译: 本文描述了用于流体输注系统的监视器装置及其操作,显示和数据处理特性。 监测装置的一个实施例用于具有胰岛素输注泵和连续葡萄糖传感器发射器的胰岛素输注系统中。 监视器装置被配置为无线床边监视器,其从诸如输液泵或传感器发射器的流体输注系统中的装置无线地接收状态数据。 监视器设备支持许多用户界面功能,警报/警报功能和图形显示功能,其中这些功能可提高监视器设备的整体操作和用户友好性。 例如,监视器设备可以生成状态图标,其图形地指示输注系统中的设备的可耗费操作量(例如,电池充电,流体存储器容积,或校准或更换周期)的剩余时间。 监视器装置还可以基于由监视器装置接收的经验测量数据来估计被监视患者的生理特征的未来测量。
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