-
公开(公告)号：US20090022755A1
公开(公告)日：2009-01-22
申请号：US11909992
申请日：2006-03-24
申请人： Brenda Barth , Ajay Bhatia , Mark Alderson , Jean-Francois L. Maisonneuve , Yves Lobet , Florence Bernadette Nozay , Martine Marchand , Pascal Mettens , Yasir A. Skeiky , Peter Probst
发明人： Brenda Barth , Ajay Bhatia , Mark Alderson , Jean-Francois L. Maisonneuve , Yves Lobet , Florence Bernadette Nozay , Martine Marchand , Pascal Mettens , Yasir A. Skeiky , Peter Probst
CPC分类号： A61K39/118 , A61K2039/55572 , A61K2039/55577 , C07K14/295
摘要： The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention and diagnosis of Chlamydia infection.
摘要翻译： 本发明涉及包含衣原体属的蛋白质或多核苷酸的组合物，特别是编码它们的蛋白质或多核苷酸的组合，以及用于治疗，预防和诊断衣原体感染的蛋白质或多核苷酸的方法。
-
公开(公告)号：US08541007B2
公开(公告)日：2013-09-24
申请号：US12974428
申请日：2010-12-21
申请人： Mark Alderson , Ajay Bhatia , Yves Lobet , Brenda Maisonneuve , Jean-Francois L Maisonneuve , Martine Marchand , Pascal Mettens , Florence Bernadette Nozay , Peter Probst , Samira H Skeiky
发明人： Mark Alderson , Ajay Bhatia , Yves Lobet , Brenda Maisonneuve , Jean-Francois L Maisonneuve , Martine Marchand , Pascal Mettens , Florence Bernadette Nozay , Peter Probst , Yasir A Skeiky
IPC分类号： A61K39/118
CPC分类号： A61K39/118 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , G01N33/56927
摘要： The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention and diagnosis of Chlamydia infection.
摘要翻译： 本发明涉及包含衣原体属的蛋白质或多核苷酸的组合物，特别是编码它们的蛋白质或多核苷酸的组合，以及用于治疗，预防和诊断衣原体感染的蛋白质或多核苷酸的方法。
-
公开(公告)号：US20100172927A1
公开(公告)日：2010-07-08
申请号：US12442538
申请日：2007-10-03
申请人： Mark Alderson , Rhea Coler , Yves Lobet , Jean-Francois L. Maisonneuve , Pascal Mettens , Peter Probst , Steven Reed
发明人： Mark Alderson , Rhea Coler , Yves Lobet , Jean-Francois L. Maisonneuve , Pascal Mettens , Peter Probst , Steven Reed
IPC分类号： A61K39/118 , A61P31/04 , A61P27/00 , C07K14/295
CPC分类号： A61K39/118 , A61K2039/53 , A61K2039/54 , A61K2039/55555 , A61K2039/55566 , A61K2039/55572 , A61K2039/55577
摘要： Methods and compositions for the treatment or prevention of ocular Chlamydia trachomatis infection. Compositions comprise one or more Chlamydia trachomatis proteins, immunogenic fragments thereof or polynucleotides encoding such proteins or fragments.
摘要翻译： 用于治疗或预防眼沙眼衣原体感染的方法和组合物。 组合物包含一种或多种沙眼衣原体蛋白，其免疫原性片段或编码这种蛋白质或片段的多核苷酸。
-
公开(公告)号：US06607731B1
公开(公告)日：2003-08-19
申请号：US09565501
申请日：2000-05-05
申请人： Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. Skeiky , Ajay Bhatia , Rhea Coler , Peter Probst
发明人： Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. Skeiky , Ajay Bhatia , Rhea Coler , Peter Probst
IPC分类号： A61K39008
CPC分类号： C07K14/44 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00 , Y02A50/41
摘要： Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
-
5.发明授权公开(公告)号：US08263089B2
公开(公告)日：2012-09-11
申请号：US11928873
申请日：2007-10-30
申请人： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
发明人： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
CPC分类号： C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
摘要翻译： 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。
-
公开(公告)号：US20080317772A1
公开(公告)日：2008-12-25
申请号：US11928855
申请日：2007-10-30
申请人： Ajay Bhatia , Yasir A.W. Skeiky , Peter Probst
发明人： Ajay Bhatia , Yasir A.W. Skeiky , Peter Probst
CPC分类号： C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
-
公开(公告)号：US06638517B2
公开(公告)日：2003-10-28
申请号：US09874923
申请日：2001-06-04
申请人： Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. W. Skeiky , Ajay Bhatia , Rhea N. Coler , Peter Probst , Mark Brannon
发明人： Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. W. Skeiky , Ajay Bhatia , Rhea N. Coler , Peter Probst , Mark Brannon
IPC分类号： A61K39008
CPC分类号： C07K14/44 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00 , Y02A50/41
摘要： Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
-
公开(公告)号：US06613337B1
公开(公告)日：2003-09-02
申请号：US09639206
申请日：2000-08-14
申请人： Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. W. Skeiky , Ajay Bhatia , Rhea Coler , Peter Probst
发明人： Steven G. Reed , Antonio Campos-Neto , John R. Webb , Davin C. Dillon , Yasir A. W. Skeiky , Ajay Bhatia , Rhea Coler , Peter Probst
IPC分类号： A61K39008
CPC分类号： C07K14/44 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00 , Y02A50/41
摘要： Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
-
9.发明授权公开(公告)号：US08052975B2
公开(公告)日：2011-11-08
申请号：US11929665
申请日：2007-10-30
申请人： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
发明人： Ajay Bhatia , Yasir A. W. Skeiky , Peter Probst
IPC分类号： A61K39/00 , A61K39/38 , A61K39/02 , A61K39/118 , A61K45/00 , A61K38/00 , C07K14/00 , C07K16/00 , C07K17/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00 , C07K1/00
CPC分类号： C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
摘要翻译： 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。
-
公开(公告)号：US06447779B1
公开(公告)日：2002-09-10
申请号：US09288594
申请日：1999-04-08
申请人： Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Steven P. Fling
发明人： Peter Probst , Ajay Bhatia , Yasir A. W. Skeiky , Steven P. Fling
IPC分类号： A61K3902
CPC分类号： C07K14/295 , A61K39/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
摘要翻译： 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。
-
-
-
-
-
-
-
-
-
搜索结果
31 条记录 (耗时 0.065 秒)