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16 条记录 (耗时 0.022 秒)

    Dry powder inhalation apparatus
    1.
    发明授权
    Dry powder inhalation apparatus 有权
    干粉吸入装置

    公开(公告)号：US08651103B2

    公开(公告)日：2014-02-18

    申请号：US10574386

    申请日：2004-10-02

    申请人： Brian Barney ,  David O'Leary ,  Rachel Striebig

    发明人： Brian Barney ,  David O'Leary ,  Rachel Striebig

    IPC分类号： A61M16/00 ,  A61M15/00

    CPC分类号： A61M15/0091 ,  A61M15/0026 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/0096 ,  A61M2016/0024 ,  A61M2202/064 ,  A61M2205/583 ,  A61M2205/8206

    摘要： The invention relates to dry powder inhalation apparatus usually operable by breath of a user which provides for controlled and smooth transfer of medicament during multiple actuations by a user. A mechanism of the apparatus for achieving this controlled and smooth transfer includes a device (4) normally held adjacent a reservoir for receiving medicament in a cup or receptacle (15) and which is generally movable transversely of a longitudinal axis of the apparatus to delivery channels of the apparatus. This bodily shifting of the device (4) is achieved by a yoke acting on an abutment (16) thereof. Spillage of medicament in the apparatus is avoided.

    摘要翻译： 本发明涉及通常由用户的呼吸操作的干粉吸入装置，其在用户的多次致动期间提供药物的受控和平滑的转移。 用于实现这种受控和平稳转移的装置的机构包括通常保持在容器附近的装置（4），用于接收在杯子或容器（15）中的药物，并且其通常可以横向于装置的纵向轴线移动到输送通道 的装置。 设备（4）的这种身体移动通过作用在其基台（16）上的轭来实现。 避免了药物在装置中的溢出。

    Pre-metered dose magazine for dry powder inhaler
    3.
    发明授权
    Pre-metered dose magazine for dry powder inhaler 失效
    用于干粉吸入器的预定剂量杂志

    公开(公告)号：US07503324B2

    公开(公告)日：2009-03-17

    申请号：US10783796

    申请日：2004-02-20

    申请人： Brian Barney ,  David O'Leary ,  Esther Perea-Borobio ,  Andrew Dickson ,  Sophia Chew ,  Rachel Striebig

    发明人： Brian Barney ,  David O'Leary ,  Esther Perea-Borobio ,  Andrew Dickson ,  Sophia Chew ,  Rachel Striebig

    IPC分类号： A61M15/00 ,  A61M16/00

    CPC分类号： A61M15/0045 ,  A61M15/0025 ,  A61M15/0035 ,  A61M15/0043 ,  A61M15/0048 ,  A61M15/0051 ,  A61M15/0061 ,  A61M15/0068 ,  A61M2202/064

    摘要： A dry powder inhaler including a housing having a mouthpiece and a delivery passageway connected to the mouthpiece, a magazine positioned within the housing and including a plurality of reservoirs for holding doses of dry powder, and wherein the magazine is movable within the housing so that the reservoirs are sequentially positioned within the delivery passageway of the housing upon movement of the magazine, a cover connected to the housing and movable to open and close the mouthpiece of the housing, and a rake connected to the cover, extending into the housing and engageable with the magazine so that, upon the cover being moved to open the mouthpiece, the rake moves the magazine and causes one of the reservoirs of the magazine to be positioned within the delivery passageway.

    摘要翻译： 一种干粉吸入器，包括具有接口管和连接到接口管的输送通道的壳体，定位在壳体内的储存器，并且包括用于保持剂量的干粉末的多个储存器，并且其中该盒可在壳体内移动， 储存器在料仓移动时顺序地定位在壳体的输送通道内，盖子连接到壳体并可移动以打开和关闭壳体的接口，以及连接到盖的耙子，延伸到壳体中并可与 使得当盖子被移动以打开接口管时，耙子移动杂物盒并使得盒子中的一个储存器定位在输送通道内。

    Dry Powder Inhalation Apparatus
    4.
    发明申请
    Dry Powder Inhalation Apparatus 有权
    干粉吸入装置

    公开(公告)号：US20080314383A1

    公开(公告)日：2008-12-25

    申请号：US10574386

    申请日：2004-10-02

    申请人： Brian Barney ,  David O'Leary ,  Rachel Striebig

    发明人： Brian Barney ,  David O'Leary ,  Rachel Striebig

    IPC分类号： A61M11/00

    CPC分类号： A61M15/0091 ,  A61M15/0026 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/0096 ,  A61M2016/0024 ,  A61M2202/064 ,  A61M2205/583 ,  A61M2205/8206

    摘要： The invention relates to dry powder inhalation apparatus usually operable by breath of a user which provides for controlled and smooth transfer of medicament during multiple actuations by a user. A mechanism of the apparatus for achieving this controlled and smooth transfer includes a device (4) normally held adjacent a reservoir for receiving medicament in a cup or receptacle (15) and which is generally movable transversely of a longitudinal axis of the apparatus to delivery channels of the apparatus. This bodily shifting of the device (4) is achieved by a yoke acting on an abutment (16) thereof. Spillage of medicament in the apparatus is avoided.

    摘要翻译： 本发明涉及通常由用户的呼吸操作的干粉吸入装置，其在用户的多次致动期间提供药物的受控和平滑的转移。 用于实现这种受控和平稳转移的装置的机构包括通常保持在容器附近的装置（4），用于接收在杯子或容器（15）中的药物，并且其通常可以横向于装置的纵向轴线移动到输送通道 的装置。 设备（4）的这种身体移动通过作用在其基台（16）上的轭来实现。 避免了药物在装置中的溢出。

    Breath-enhanced ultrasonic nebulizer and dedicated unit dose ampoule
    5.
    发明授权
    Breath-enhanced ultrasonic nebulizer and dedicated unit dose ampoule 失效
    呼吸增强超声雾化器和专用单位剂量安瓿

    公开(公告)号：US07261102B2

    公开(公告)日：2007-08-28

    申请号：US10487611

    申请日：2002-08-30

    申请人： Brian Barney ,  Sophia Chew ,  Paul Fairburn ,  David O'Leary ,  Rachel Striebig

    发明人： Brian Barney ,  Sophia Chew ,  Paul Fairburn ,  David O'Leary ,  Rachel Striebig

    IPC分类号： A61M11/00

    CPC分类号： A61M15/0028 ,  A61M15/0016 ,  A61M15/0018 ,  A61M15/0033 ,  A61M15/0085 ,  A61M16/208 ,  A61M2205/14

    摘要： A medicament delivery system comprises a nebulizer device, an open-faced mist chamber-defining element having a tubular input/output port, a tubular inhalation port connecting to the output port of the mist chamber-defining element, and a sealed unit dose ampoule adapted to fit within the mist chamber-defining element. The nebulizer device includes an ultrasonic transducer responsive to applied electrical energy to generate ultrasonic energy, an ultrasonic transmission horn between an input energy surface at an input end and an energy delivery surface at an output end. The sealed unit dose ampoule can be placed directly into the nebulizer device and acts as both the dose cup and baffle, so that the chance of spillage of drug and the number of components to be cleaned are minimized.

    摘要翻译： 药物输送系统包括雾化器装置，具有管状输入/输出端口的开放式雾室限定元件，连接到雾室限定元件的输出端口的管状吸入口，以及适于 以配合在雾室限定元件内。 喷雾器装置包括响应于所施加的电能以产生超声能量的超声换能器，在输入端的输入能量表面和输出端的能量输送表面之间的超声波传播喇叭。 密封单位剂量安瓿可以直接放置在雾化器装置中并充当剂量杯和挡板，使得药物溢出的可能性和待清洁的组分数量最小化。

    Breath-enhanced ultrasonic nebulizer and dedicated unit dose ampoule
    7.
    发明申请
    Breath-enhanced ultrasonic nebulizer and dedicated unit dose ampoule 失效
    呼吸增强超声雾化器和专用单位剂量安瓿

    公开(公告)号：US20050081845A1

    公开(公告)日：2005-04-21

    申请号：US10487611

    申请日：2002-08-30

    申请人： Brian Barney ,  Sophia Chew ,  Paul Fairburn ,  David O'Leary ,  Rachel Striebig

    发明人： Brian Barney ,  Sophia Chew ,  Paul Fairburn ,  David O'Leary ,  Rachel Striebig

    IPC分类号： A61M11/00 ,  A61M15/00 ,  A61M16/20 ,  B05B17/06

    CPC分类号： A61M15/0028 ,  A61M15/0016 ,  A61M15/0018 ,  A61M15/0033 ,  A61M15/0085 ,  A61M16/208 ,  A61M2205/14

    摘要： A medicament delivery system comprises a nebulizer device, an open-faced mist chamber-defining element having a tubular input/output port, a tubular inhalation port connecting to the output port of the mist chamber-defining element, and a sealed unit dose ampoule adapted to fit within the mist chamber-defining element. The nebulizer device includes an ultrasonic transducer responsive to applied electrical energy to generate ultrasonic energy, an ultrasonic transmission horn between an input energy surface at an input end and an energy delivery surface at an output end. The sealed unit dose ampoule can be placed directly into the nebulizer device and acts as both the dose cup and baffle, so that the chance of spillage of drug and the number of components to be cleaned are minimized. The unit dose ampoule has a conical base to allow ultrasonic energy conducted from the ultrasonic system to be concentrated at the base of the ampoule. The inhalation port includes an inhalation valve and an exhalation valve.

    摘要翻译： 药物输送系统包括雾化器装置，具有管状输入/输出端口的开放式雾室限定元件，连接到雾室限定元件的输出端口的管状吸入口，以及适于 以配合在雾室限定元件内。 喷雾器装置包括响应于所施加的电能以产生超声能量的超声换能器，在输入端的输入能量表面和输出端的能量输送表面之间的超声波传播喇叭。 密封单位剂量安瓿可以直接放置在雾化器装置中并充当剂量杯和挡板，使得药物溢出的可能性和待清洁的组分数量最小化。 单位剂量安瓿具有锥形基底，以允许从超声系统传导的超声能量集中在安瓿的底部。 吸入口包括吸入阀和呼气阀。

    De-agglomerator for breath-actuated dry powder inhaler
    8.
    发明授权
    De-agglomerator for breath-actuated dry powder inhaler 有权

    公开(公告)号：US06748947B2

    公开(公告)日：2004-06-15

    申请号：US09888281

    申请日：2001-06-23

    申请人： Laurence Keane ,  David O'Leary

    发明人： Laurence Keane ,  David O'Leary

    IPC分类号： B65D8306

    CPC分类号： A61M15/0086 ,  A61M15/0008 ,  A61M15/0045 ,  A61M15/0048 ,  A61M15/0068 ,  A61M15/0091 ,  A61M2202/064 ,  A61M2206/16 ,  G06M1/246

    摘要： A de-agglomerator is provided for use with a breath-actuated dry powder inhaler for breaking up aggregates and micronizing particles of dry powder prior to inhalation of the powder by a patient using the inhaler. The de-agglomerator includes an inner wall defining a swirl chamber extending along an axis from a first end to a second end, a dry powder supply port, an inlet port, and an outlet port. The supply port is in the first end of the swirl chamber for providing fluid communication between a dry powder delivery passageway of an inhaler and the first end of the swirl chamber. The inlet port is in the inner wall of the swirl chamber adjacent to the first end of the swirl chamber and provides fluid communication between a region exterior to the de-agglomerator and the swirl chamber. The outlet port provides fluid communication between the second end of the swirl chamber and a region exterior to the de-agglomerator, whereby a breath induced low pressure at the outlet port causes air flows into the swirl chamber through the dry powder supply port and the inlet port. The air flows collide with each other and with the wall of the swirl chamber prior to exiting through the outlet port, such that any powder entrained in the air flows is broken down and micronized. The de-agglomerator further includes vanes at the first end of the swirl chamber for creating additional collisions and impacts of entrained powder.

    Dose counter for medicament inhaler
    10.
    发明授权
    Dose counter for medicament inhaler 有权
    用于药物吸入器的剂量计数器

    公开(公告)号：US06701917B2

    公开(公告)日：2004-03-09

    申请号：US09888198

    申请日：2001-06-23

    申请人： David O'Leary

    发明人： David O'Leary

    IPC分类号： A61M1100

    CPC分类号： A61M15/0045 ,  A61M15/0008 ,  A61M15/0048 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/0078 ,  A61M15/0086 ,  A61M15/0091 ,  A61M15/0093 ,  A61M15/0096 ,  A61M2202/064 ,  A61M2206/16 ,  G06M1/04 ,  G06M1/246

    摘要： A new and improved inhaler includes an accurate and consistent mechanical dose metering system that dispenses dry powdered medicament in discrete amounts or doses for patient inhalation, a pressure relief system that manages pressure within a medicament reservoir of the inhaler to ensure consistently dispensed doses, and a dose counting system indicating the number of doses remaining in the inhaler.

    摘要翻译： 新的改进的吸入器包括准确和一致的机械剂量计量系统，其分配用于患者吸入的离散量或剂量的干燥粉末药物，压力释放系统，其管理吸入器的药物储存器内的压力以确保一致分配的剂量，以及 剂量计数系统，指示吸入器中剩余的剂量数。