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    MEDICAL DEVICE WITH THERAPEUTIC AGENTS
    2.
    发明申请
    MEDICAL DEVICE WITH THERAPEUTIC AGENTS 有权
    具有治疗药物的医疗器械

    公开(公告)号：US20080051737A1

    公开(公告)日：2008-02-28

    申请号：US11930722

    申请日：2007-10-31

    申请人： Ram Paul ,  Daniel Sirota ,  Paul Amarant

    发明人： Ram Paul ,  Daniel Sirota ,  Paul Amarant

    IPC分类号： A61M25/00 ,  A61L29/16

    CPC分类号： A61M25/00 ,  A61M25/0017 ,  A61M2025/0057

    摘要： A medical device is adapted for at least partial implantation into a body and includes first and second sections along the length of the device. A first therapeutic agent is associated with the first section and a second therapeutic agent is associated with the second section. The first therapeutic agent can be one or more antiproliferative, such as paclitaxel, a paclitaxel derivative, or a paclitaxel pro-drug, anti-coagulant, antithrombotic, thrombolytic, fibrinolytic, or combination thereof. The second therapeutic agent can be one or more antimicrobials, such as one or more antibiotics. Each of the first and second therapeutic agents can either be posited on one or more surfaces of the respective section, or impregnated within the section. The device can include a separator to space the first and second sections. A method of making a medical device and a method of establishing access to a vessel within a body are also provided.

    摘要翻译： 医疗装置适于至少部分植入体内，并且包括沿着装置长度的第一和第二部分。 第一治疗剂与第一部分相关联，第二治疗剂与第二部分相关联。 第一种治疗剂可以是一种或多种抗增殖剂，例如紫杉醇，紫杉醇衍生物或紫杉醇前药，抗凝血剂，抗血栓形成剂，溶栓剂，纤维蛋白溶解剂或其组合。 第二治疗剂可以是一种或多种抗微生物剂，例如一种或多种抗生素。 第一和第二治疗剂中的每一个可以被放置在相应部分的一个或多个表面上，或浸渍在该部分内。 该装置可以包括用于分隔第一和第二部分的分离器。 还提供了制造医疗装置的方法和建立对体内容器的通路的方法。

    Anastomosis clamp
    3.
    发明申请
    Anastomosis clamp 审中-公开
    吻合钳

    公开(公告)号：US20060004392A1

    公开(公告)日：2006-01-05

    申请号：US11121604

    申请日：2005-05-04

    申请人： Paul Amarant

    发明人： Paul Amarant

    IPC分类号： A61B17/08

    CPC分类号： A61B17/11 ,  A61B2017/081 ,  A61B2017/1103 ,  A61B2017/1107

    摘要： A clamp for use in joining two vessels in end-to-end anastomosis. The clamp comprises a clamp body comprising opposing clamp members joined by a hinge. The clamp members are pivotable along the hinge to selectively maneuver the clamp between an open position and a closed position. Each of the opposing clamp members includes an opening sized for axial passage of at least a portion of a separate one of the vessels therethrough. The clamp body includes a closing mechanism for sealing the clamp when the clamp members are pivoted to the closed position, whereupon the vessels are aligned to establish fluid communication therebetween.

    摘要翻译： 用于在端对端吻合中连接两个血管的夹具。 该夹具包括夹具主体，其包括由铰链连接的相对的夹紧构件。 夹紧构件可沿着铰链枢转以选择性地在打开位置和关闭位置之间操纵夹具。 每个相对的夹紧构件包括一个开口，其尺寸用于通过其中的一个单独的容器的至少一部分的轴向通过。 夹紧体包括用于在夹紧构件枢转到关闭位置时密封夹具的关闭机构，于是容器对准以在其间建立流体连通。

    Stent having arcuate struts
    4.
    发明申请
    Stent having arcuate struts 审中-公开
    支架具有弓形支柱

    公开(公告)号：US20060004436A1

    公开(公告)日：2006-01-05

    申请号：US11171909

    申请日：2005-06-30

    申请人： Paul Amarant ,  Thomas Osborne

    发明人： Paul Amarant ,  Thomas Osborne

    IPC分类号： A61F2/06

    CPC分类号： A61F2/90 ,  A61F2/88 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0065 ,  A61F2230/0078 ,  A61F2250/0037 ,  A61F2250/0039

    摘要： Stents are provided having a circumferential element with first and second ends, a longitudinal axis, and arcuate struts disposed intermediate the ends. End portions of adjacent arcuate struts are joined by strut connections formed at the first and second ends. The struts are spaced arcuately relative to a plane that includes the longitudinal axis, such that they arc convexly or concavely relative to the plane. Another stent has a tubular main body with a longitudinal axis, first and second ends defining a lumen in communication with openings at the first and second ends, and circumferential elements disposed along the tubular main body longitudinal axis, whereby one or more link members join two or more of the circumferential elements. Methods of using a stent having a circumferential element having arcuate struts connected by strut connections are also provided.

    摘要翻译： 提供具有具有第一和第二端部的周向元件，纵向轴线以及设置在端部中间的弓形支柱的支架。 相邻弓形支柱的端部通过形成在第一端和第二端的支柱连接件连接。 支柱相对于包括纵向轴线的平面呈弧形间隔开，使得它们相对于该平面凸起或凹入。 另一个支架具有带纵向轴线的管状主体，第一和第二端部限定与第一和第二端部处的开口相连通的内腔以及沿管状主体纵向轴线设置的周向元件，由此一个或多个连杆构件连接两个 或更多的周向元件。 还提供了使用具有通过支柱连接连接的具有弓形支柱的圆周元件的支架的方法。

    Percutaneous anastomosis connection system
    5.
    发明申请
    Percutaneous anastomosis connection system 审中-公开
    经皮吻合连接系统

    公开(公告)号：US20060004393A1

    公开(公告)日：2006-01-05

    申请号：US11121606

    申请日：2005-05-04

    申请人： Paul Amarant

    发明人： Paul Amarant

    IPC分类号： A61B17/08

    CPC分类号： A61B17/11 ,  A61B2017/081 ,  A61B2017/1103 ,  A61B2017/1107

    摘要： A system for providing an end-to-end anastomosis connection between two vessels. The system comprises first and second hollow tubes. Each of the tubes has a first end that is attachable to a free end of a separate one of the two vessels, and a second end that comprises a connector. The respective connectors are sized and shaped for engagement to each other, such that a fluid-tight connection can be established therebetween.

    摘要翻译： 一种用于在两个血管之间提供端对端吻合连接的系统。 该系统包括第一和第二中空管。 每个管具有可连接到两个容器中的单独一个的自由端的第一端，以及包括连接器的第二端。 相应的连接器的尺寸和形状被设计成彼此接合，使得它们之间可以建立流体密封的连接。

    Double-ended conduit with graded locking sleeves
    6.
    发明申请
    Double-ended conduit with graded locking sleeves 审中-公开
    带分级锁定套管的双端导管

    公开(公告)号：US20060004394A1

    公开(公告)日：2006-01-05

    申请号：US11121611

    申请日：2005-05-04

    申请人： Paul Amarant

    发明人： Paul Amarant

    IPC分类号： A61B17/08

    CPC分类号： A61B17/11 ,  A61B2017/081 ,  A61B2017/088 ,  A61B2017/1103 ,  A61B2017/1107

    摘要： An apparatus for joining two vessels in end-to-end anastomosis comprises a hollow tubular conduit having two ends, and a pair of opposing locking sleeves disposed along an outer surface of the conduit and at least partially moveable thereover. At least one of the conduit ends may include a grasping member, such as a barbed ring, adjacent the end. Each of the locking members has an inner diameter related to the outer diameter of a respective conduit end such that a vessel positionable between said locking member and said conduit end is substantially locked thereby, to inhibit disengagement of said vessel end from said apparatus.

    摘要翻译： 用于在端对端吻合中连接两个血管的装置包括具有两个端部的中空管状导管和沿着导管的外表面设置并且至少部分地可移动的一对相对的锁定套管。 导管末端中的至少一个可以包括靠近端部的抓握构件，例如有倒钩的环。 每个锁定构件具有与相应管道端部的外径相关的内径，使得可定位在所述锁定构件和所述导管端部之间的容器基本上被锁定，从而阻止所述容器端部与所述装置的分离。