-
公开(公告)号：US06302919B1
公开(公告)日：2001-10-16
申请号：US09358130
申请日：1999-07-20
申请人： Brian Chambers , Adam Sampson , Matt McDermott , Byron Knight , Gunars E. Valkirs , Howard J. Kirchick
发明人： Brian Chambers , Adam Sampson , Matt McDermott , Byron Knight , Gunars E. Valkirs , Howard J. Kirchick
IPC分类号： B01D2126
CPC分类号： G01N1/4077 , B01L3/5021
摘要： A filtration device, apparatus, and method of filtration useful for filtering liquid samples are disclosed wherein filtration occurs opposite the direction of centrifugal force. The filtration device is placed within a container that contains the liquid sample to be filtered. Together, the filtration device and the container comprise the filtration apparatus. Centrifugation forces the liquid sample present in the container to enter the filtration device, thereby effecting filtration. The vertical position of the filtration device is fixed within this container during filtration.
摘要翻译： 公开了用于过滤液体样品的过滤装置，装置和过滤方法，其中过滤与离心力方向相反。 将过滤装置放置在容纳要过滤的液体样品的容器内。 过滤装置和容器一起包括过滤装置。 离心迫使存在于容器中的液体样品进入过滤装置，从而进行过滤。 在过滤期间，过滤装置的垂直位置固定在该容器内。
-
2.发明授权公开(公告)号：US07427490B2
公开(公告)日：2008-09-23
申请号：US10225082
申请日：2002-08-20
IPC分类号： G01N33/00
CPC分类号： G01N33/6893 , G01N33/573 , G01N2333/96486 , G01N2800/2871 , Y10S436/811
摘要： The present invention relates to methods for the diagnosis and evaluation of stroke and transient ischemic attacks. In a particular aspect, patient samples are analyzed for the presence or amount of a panel of markers comprising one or more specific markers for cerebral injury and one or more non-specific markers for cerebral injury. In an alternative aspect, samples are analyzed for B-type natriuretic peptide. A variety of markers are disclosed for assembling a panel for such diagnosis and evaluation. In various aspects, the invention provides methods for early detection and differentiation of stroke types and transient ischemic attacks, for determining the prognosis of a patient presenting with stroke symptoms, and identifying a patient at risk for cerebral vasospasm. Invention methods provide rapid, sensitive and specific assays to greatly increase the number of patients that can receive beneficial stroke treatment and therapy, and reduce the costs associated with incorrect stroke diagnosis.
摘要翻译： 本发明涉及中风和短暂性脑缺血发作的诊断和评估方法。 在特定方面，分析患者样品的一组标志物的存在或量，其包含一种或多种用于脑损伤的特异性标志物和一种或多种用于脑损伤的非特异性标志物。 在另一方面，分析B型利尿钠肽的样品。 公开了用于组装用于这种诊断和评估的面板的各种标记。 在各个方面，本发明提供了用于早期检测和分化卒中类型和短暂性脑缺血发作的方法，用于确定患有中风症状的患者的预后，以及鉴定患有脑血管痉挛风险的患者。 本发明方法提供快速，灵敏和特异性的测定以大大增加可以接受有益的中风治疗和治疗的患者的数量，并且降低与不正确的中风诊断相关的成本。
-
3.发明授权公开(公告)号：US07608406B2
公开(公告)日：2009-10-27
申请号：US10875800
申请日：2004-06-23
IPC分类号： G01N33/53
CPC分类号： G01N33/6896 , G01N2800/2871
摘要： The present invention relates to methods for the diagnosis and evaluation of stroke and transient ischemic attacks. A variety of markers are disclosed for assembling a panel for such diagnosis and evaluation. In various aspects, the invention provides methods for early detection and differentiation of stroke types and transient ischemic attacks, for determining the prognosis of a patient presenting with stroke symptoms, and identifying a patient at risk for cerebral vasospasm. Invention methods provide rapid, sensitive and specific assays to greatly increase the number of patients that can receive beneficial stroke treatment and therapy, and reduce the costs associated with incorrect stroke diagnosis.
摘要翻译： 本发明涉及中风和短暂性脑缺血发作的诊断和评估方法。 公开了用于组装用于这种诊断和评估的面板的各种标记。 在各个方面，本发明提供了用于早期检测和分化卒中类型和短暂性脑缺血发作的方法，用于确定患有中风症状的患者的预后，以及鉴定患有脑血管痉挛风险的患者。 本发明方法提供快速，灵敏和特异性的测定以大大增加可以接受有益的中风治疗和治疗的患者的数量，并且降低与不正确的中风诊断相关的成本。
-
4.发明授权Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology 失效在使用磁选分离技术的测定中可磁化颗粒的洗涤，再悬浮，回收和定位的方法和设备
公开(公告)号：US5888835A
公开(公告)日：1999-03-30
申请号：US644909
申请日：1996-05-10
IPC分类号： B03C1/28 , G01N33/543 , G01N33/553 , G01N35/00
CPC分类号： G01N33/54326 , B03C1/288 , G01N35/0098 , Y10S436/807 , Y10S436/809 , Y10T436/113332
摘要： Method and apparatus for enabling resuspension wash and magnetic localization of sample components bound to particles with magnetic properties in reaction vessels during separation and wash for enhanced chemiluminescent signal generation in biomedical assays. The assays involve moving reaction vessels past magnetic arrays that partially localized the particles prior to passing a gap where washing occurs, with or without resuspension, after separating out the unbound components and liquid. The band of particles is further localized by a focusing magnet at the end of the array prior to dosing the vessel with acid for chemiluminescent purposes. A block of soft magnetic material is employed in place of a magnet in the gap to minimize magnetic strength at the gap. Trimmed magnets adjacent the gap cause left, then right, particle shifting that localizes the magnetizable particles. The gap enables improved resuspension by wash, whereas the localized particles enable more efficient resuspension by reagent.
摘要翻译： 用于在分离和洗涤期间使得能够重新悬浮洗涤和磁性定位结合到反应容器中的具有磁性的颗粒的样品组分的洗涤和磁定位的方法和装置，用于生物医学测定中增强的化学发光信号产生。 测定包括使分离出未结合的组分和液体之后，将反应容器移动通过磁性阵列，该磁性阵列在通过发生洗涤的间隙之前部分地定位该颗粒，同时具有或不具有重新悬浮。 在用酸化学发光目的给容器给料之前，颗粒带在进一步定位在阵列末端的聚焦磁体。 使用一块软磁性材料代替间隙中的磁体，以使间隙处的磁强度最小化。 邻近间隙的修整磁体会导致左边，然后是右边的颗粒移动，使可磁化的颗粒定位。 该间隙能够通过洗涤改善再悬浮，而局部颗粒使得能够通过试剂更有效的再悬浮。
-
公开(公告)号：USD321940S
公开(公告)日：1991-11-26
申请号：US383136
申请日：1989-07-20
-
-
-
-
搜索结果
5 条记录 (耗时 0.028 秒)
