Method of matching retention times among multiple chromatographic system
    2.
    发明授权
    Method of matching retention times among multiple chromatographic system 有权
    匹配多个色谱系统保留时间的方法

    公开(公告)号:US06915227B2

    公开(公告)日:2005-07-05

    申请号:US10722994

    申请日:2003-11-26

    CPC分类号: G01N30/8665 G01N30/8672

    摘要: A data manipulation method to make local chromatography data more usable and comparable to a reference. The method provides time axis correction to better match local data to a reference of the same time scale, time axis transformation to correspond more directly to a reference based on a different time scale, and response axis correction to better match a reference of the same or different response scale, while maintaining the original peak areas. The method may be used along or concurrently with other data manipulation technique to facilitate operations such as searching, matching, visual comparison, mathematical manipulation, and pattern recognition of chromatographic data.

    摘要翻译: 一种数据操作方法,使局部色谱数据更为可用,与参照物相当。 该方法提供时间轴校正以更好地将本地数据与相同时标的参考相匹配,时间轴转换以基于不同时间尺度更直接地对应于参考,以及响应轴校正以更好地匹配相同或者 不同的响应规模,同时保持原有的峰值区域。 该方法可以与其他数据操作技术一起使用或同时使用,以便于诸如搜索,匹配,视觉比较,数学操作和色谱数据的模式识别等操作。

    Solvent dumping apparatus
    5.
    发明授权
    Solvent dumping apparatus 失效
    溶剂倾倒装置

    公开(公告)号:US4517824A

    公开(公告)日:1985-05-21

    申请号:US510127

    申请日:1983-07-01

    申请人: Bruce D. Quimby

    发明人: Bruce D. Quimby

    IPC分类号: G01N30/62 G01N30/84 G01N31/08

    摘要: A solvent dumping apparatus is described having an inlet enclosure coupled to the inlet of a detector and an outlet enclosure coupled to the outlet of a detector. Venting means are provided for both enclosures, one of which is controllable; means are provided for introducing sample gas into the inlet enclosure; and means are provided for introducing gas into the outlet enclosure. During a detection mode, at least one of the venting means is so adjusted as to cause sample gas to flow through the detector and out the venting means for the outlet enclosure, and during a diversionary mode, at least one of the venting means is so adjusted as to cause the gas introduced into the outlet enclosure to pass back through the detector and carry any sample gas out through the venting means for the inlet enclosure. In preferred forms of the invention, one of the venting means is a back pressure regulator.

    摘要翻译: 描述了具有耦合到检测器的入口的入口外壳和耦合到检测器的出口的出口外壳的溶剂倾倒装置。 为两个外壳提供通风装置,其中一个可控制; 提供用于将样品气体引入入口外壳的装置; 并且提供用于将气体引入出口外壳中的装置。 在检测模式期间,排气装置中的至少一个被调节成使得样品气体流过检测器并排出出口外壳的通风装置,并且在分流模式期间,至少一个排气装置是如此 调整为使引入出口外壳的气体通过检测器返回,并将任何样品气体通过用于入口外壳的排气装置输出。 在本发明的优选形式中,排气装置之一是背压调节器。

    Connector for analytical devices
    6.
    发明授权
    Connector for analytical devices 有权
    分析仪器连接器

    公开(公告)号:US07507336B2

    公开(公告)日:2009-03-24

    申请号:US11111243

    申请日:2005-04-20

    IPC分类号: B01D15/08

    摘要: A connector element for use with analytical devices is provided. The connector element includes a cavity for receiving a sealing member, and an access element for providing access to the sealing member when disposed in the cavity, e.g., for dislodging the sealing member from the connector element. Also provided are analytical devices that include the connector element, as well as methods of using the same.

    摘要翻译: 提供了一种用于分析装置的连接器元件。 连接器元件包括用于接收密封构件的空腔和用于当设置在空腔中时提供对密封构件的通路的进入构件,例如用于将密封构件从连接器元件移出。 还提供了包括连接器元件的分析装置,以及使用它们的方法。

    Retention factor database
    7.
    发明授权
    Retention factor database 失效
    保留因子数据库

    公开(公告)号:US6153438A

    公开(公告)日:2000-11-28

    申请号:US859630

    申请日:1997-05-20

    摘要: A method for identifying analytes of interest by referencing to a retention factor database corresponding to a plurality of identified analytes that is independent of column dimensions and carrier gas type while dependent upon stationary phase type ratio and a relative temperature program. The retention factor database is generated on a reference GC system in which the column head pressure is adjusted to ensure high reproducibility of retention times by locking the column void time and/or the retention time of an identified analyte to a specific value such that accurate retention factors (k) can be calculated in accordance with the formula: ##EQU1## where VT is the void time of the column having a specified stationary phase and phase coating installed in a GC system operating in accordance to a specified temperature program (where time is expressed in units of column void time).

    摘要翻译: 通过参考与多个识别的分析物相对应的保留因子数据库来识别感兴趣的分析物的方法,其独立于列尺寸和载气类型,同时依赖于固定相型比率和相对温度程序。 保留因子数据库是在参考GC系统上产生的,其中柱头压力被调整以通过将所确定的分析物的柱空隙时间和/或保留时间锁定到特定值来确保保留时间的高再现性,使得精确保留 因子(k)可以根据以下公式计算:其中VT是具有指定的固定相和相涂层的柱的空隙时间,其安装在根据指定温度程序操作的GC系统中(时间以单位表示 的列空闲时间)。

    Method, apparatus, and article of manufacture for enhanced intergration
of signals
    8.
    发明授权
    Method, apparatus, and article of manufacture for enhanced intergration of signals 失效
    用于增强信号整合的方法,装置和制造

    公开(公告)号:US6112161A

    公开(公告)日:2000-08-29

    申请号:US932150

    申请日:1997-09-17

    IPC分类号: G01N30/86

    摘要: A method, apparatus, and article of manufacture for enhanced integration of signals, such as those generated by chromatographs. In one embodiment an approximate baseline used for integration of a signal is improved to reduce error. Alternate embodiments filter drift, noise, or both from a signal prior to integration or simulated distillation. The signals are processed according to a computer program stored in a memory. The methods include steps for subtracting an approximate baseline from the signal, defining a noise band in the resulting difference, and forming a composite baseline by substituting signal data for baseline data wherever the difference does not exceed the threshold, thus leaving the parts of the approximate baseline that correspond to signal peaks unchanged.

    摘要翻译: 用于增强信号集成的方法,装置和制品,例如由色谱仪产生的信号。 在一个实施例中,用于信号积分的近似基线被改进以减少误差。 替代实施例在集成或模拟蒸馏之前从信号滤波漂移,噪声或二者。 信号根据存储在存储器中的计算机程序进行处理。 这些方法包括从信号中减去近似基线的步骤,在所得到的差值中定义噪声带,并通过将信号数据代入基线数据形成复合基线,无论差值不超过阈值,因此留下近似的部分 对应于信号峰的基线不变。

    Automated retention time locking
    9.
    发明授权
    Automated retention time locking 失效
    自动保留时间锁定

    公开(公告)号:US5987959A

    公开(公告)日:1999-11-23

    申请号:US36658

    申请日:1998-03-06

    IPC分类号: G01N30/32 G01N30/86 G01N30/02

    摘要: The invention provides a method for automated matching of retention times obtained using a known chromatographic method having a defined set of column parameters and operating parameters to the retention times obtained using a new chromatographic method having a new set of column parameters, wherein the retention times of components separated in accordance with the new chromatographic method are matched to the retention times set forth in the known chromatographic methods. A procedure is described to adjust head pressure to compensate for differences in a new versus the original column, carrier gas, and column outlet pressure of the known method.

    摘要翻译: 本发明提供了一种使用已知色谱法获得的保留时间自动匹配的方法,所述色谱方法具有定义的一组列参数和操作参数与使用具有新的一组列参数的新色谱方法获得的保留时间,其中保留时间 根据新的色谱方法分离的组分与已知色谱方法中列出的保留时间相匹配。 描述了一种程序来调节压头压力以补偿已知方法的新色谱柱与原始色谱柱,载气和色谱柱出口压力的差异。