Preparing live microbial samples and microorganisms for subsequent mass spectrometric measurement and evaluation

    公开(公告)号:US11480579B2

    公开(公告)日:2022-10-25

    申请号:US16464288

    申请日:2016-11-30

    IPC分类号: G01N33/68 C12Q1/18

    摘要: The invention relates to a method for the preparation of living, microbial samples and microorganisms for subsequent mass spectrometric measurement and evaluation. Findings which can be derived from such a measurement can particularly serve the faster identification of microorganisms in the microbial sample according to species/subspecies and/or the fast determination of resistance/sensitivity of the microorganisms to antimicrobial substances and/or the further characterization of microorganisms, for example in respect of pathogenicity, virulence and metabolism. According to a preferred embodiment of the invention, the preparation particularly takes place directly on a mass spectrometric sample support.