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    Robust Eye Tracking for Scanning Laser Ophthalmoscope
    4.
    发明申请
    Robust Eye Tracking for Scanning Laser Ophthalmoscope 审中-公开
    坚固的眼睛跟踪扫描激光眼镜

    公开(公告)号：US20170004344A1

    公开(公告)日：2017-01-05

    申请号：US14791088

    申请日：2015-07-02

    申请人： CANON KABUSHIKI KAISHA ,  UNIVERSITY OF ROCHESTER

    发明人： Koji Nozato ,  Kenichi Saito ,  Qiang Yang ,  Jie Zhang

    IPC分类号： G06K9/00 ,  G06K9/52 ,  G06T7/20 ,  H04N5/232 ,  G06T7/00 ,  G06K9/46

    CPC分类号： H04N5/23222 ,  A61B3/1025 ,  A61B3/113 ,  A61B3/12 ,  A61B3/14 ,  G06K9/00604 ,  G06K9/2054 ,  G06K9/522 ,  G06K2209/05 ,  G06T7/248 ,  G06T2207/30041 ,  H04N5/2258

    摘要： A system, apparatus, and method of obtaining an image of a fundus. Acquiring a reference image of the fundus at a first point in time. Acquiring a target image of the fundus at a second point in time. The target imaging area may overlap with the reference imaging area. An area of the target imaging area may be less than an area of the reference imaging area. Estimating movement of the fundus may be based upon at least the target image and the reference image. Acquiring a narrow field image of the fundus. An area of the narrow field imaging area may be less than the area of the target imaging area. A position of the narrow imaging area on the fundus may be adjusted based on the estimated movement of the fundus.

    摘要翻译： 一种获得眼底图像的系统，装置和方法。 在第一时间点获取眼底的参考图像。 在第二个时间点获取眼底的目标图像。 目标成像区域可能与参考成像区域重叠。 目标成像区域的区域可以小于参考成像区域的面积。 估计眼底的运动可以至少基于目标图像和参考图像。 获得眼底狭窄的形象。 窄场成像区域的区域可以小于目标成像区域的面积。 可以根据估计的眼底移动来调整眼底狭窄成像区域的位置。

    Image based correction of distortion from a scanner
    5.
    发明授权
    Image based correction of distortion from a scanner 有权
    基于图像校正来自扫描仪的失真

    公开(公告)号：US09485383B2

    公开(公告)日：2016-11-01

    申请号：US14096902

    申请日：2013-12-04

    申请人： CANON KABUSHIKI KAISHA ,  University of Rochester

    发明人： Koji Nozato ,  Qiang Yang

    IPC分类号： H04N1/047 ,  H04N1/04

    CPC分类号： H04N1/047 ,  H04N1/04 ,  H04N2201/04789

    摘要： System, method, and non-transitory computer readable medium encoded with instructions for imaging an object. Dividing raw data into forward scan data and backward scan data. Reversing the order of the backward scan data to produce inverted backward scan data. Determining an offset value that is associated with a maximum value of a first function based on the forward scan data and the inverted backward scan data. The forward scan data is shifted by the offset value relative to the inverted backward scan data. Producing a first image of the object that comprises the forward scan data interlaced with the inverted backward scan data. The forward scan data is shifted by the offset value relative to the inverted backward scan data.

    摘要翻译： 用用于成像对象的指令编码的系统，方法和非暂时计算机可读介质。 将原始数据划分为正向扫描数据和反向扫描数据。 反转反向扫描数据的顺序产生反向反向扫描数据。 基于前向扫描数据和反向反向扫描数据确定与第一功能的最大值相关联的偏移值。 前向扫描数据相对于反向反向扫描数据偏移偏移值。 产生包含与反向反向扫描数据隔行扫描前向数据的对象的第一图像。 正向扫描数据相对于反向反向扫描数据偏移偏移值。

    Light source modulation for a scanning microscope
    6.
    发明授权
    Light source modulation for a scanning microscope 有权
    扫描显微镜的光源调制

    公开(公告)号：US09254083B2

    公开(公告)日：2016-02-09

    申请号：US14099700

    申请日：2013-12-06

    申请人： CANON KABUSHIKI KAISHA ,  University of Rochester

    发明人： Koji Nozato ,  Qiang Yang

    IPC分类号： A61B3/14 ,  A61B3/12 ,  A61B3/13

    CPC分类号： A61B3/12 ,  A61B3/13

    摘要： Systems, method, and non-transitory computer readable medium for imaging an object. The system includes a scanner. The scanner positions a spot of light from a light source on the object along a scanning path. The scanning path includes a plurality of scan lines. The spot moves along the scanning path at a scanning velocity. The scanning velocity is not constant. The intensity of the spot of light is modulated as a function of the scanning velocity. The system includes a detector that is arranged to output data associated with positions along the scanning path. The system includes one or more processors that perform calculations. Pixels are calculated based on the output data. The image is constructed of the object based on the pixels.

    摘要翻译： 用于成像对象的系统，方法和非暂时计算机可读介质。 该系统包括扫描仪。 扫描仪沿着扫描路径将来自光源的光点定位在物体上。 扫描路径包括多条扫描线。 斑点以扫描速度沿着扫描路径移动。 扫描速度不是恒定的。 光点的强度作为扫描速度的函数进行调制。 该系统包括检测器，其被布置成输出与沿着扫描路径的位置相关联的数据。 该系统包括执行计算的一个或多个处理器。 基于输出数据计算像素。 该图像由基于像素的对象构成。

    MICROSCOPY IMAGING SYSTEM AND METHODS
    9.
    发明申请
    MICROSCOPY IMAGING SYSTEM AND METHODS 有权

    公开(公告)号：US20230022632A1

    公开(公告)日：2023-01-26

    申请号：US17812494

    申请日：2022-07-14

    申请人： University of Rochester

    发明人： Qiang Yang ,  Jennifer Hunter ,  Keith Parkins

    IPC分类号： A61B3/13 ,  A61B3/12 ,  G02B21/16 ,  G02B21/00

    摘要： A microscopy imaging system comprises a fluorescence lifetime imaging microscopy (FLIM) system comprising a pulsed light source configured to direct a plurality of excitation light pulses onto a sample, a photo detector configured to detect emitted fluorescent photons created by the plurality of excitation pulses interacting with the sample, and a FLIM data acquisition system configured to measure the time interval between the excitation light pulses and the detected emitted fluorescent photons, a scanning light microscopy (SLM) system comprising a SLM data acquisition system, a fast scanning mirror and a slow scanning mirror, wherein the mirrors are configured to scan the light pulses across the sample; and a data processing system communicatively connected to the FLIM and SLM systems. Microscopy imaging methods are also disclosed.