公开(公告)号：US11499173B2

公开(公告)日：2022-11-15

申请号：US16470030

申请日：2019-02-12

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jaewon Jang ,  Kwang Woo Lee ,  Yong Uk Shin ,  Imsang Lee

IPC: C12P13/08 ,  C12N1/20 ,  C12N9/10 ,  C12P13/06 ,  C12P13/12 ,  C12R1/15

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.

公开(公告)号：US20230203106A1

公开(公告)日：2023-06-29

申请号：US17778810

申请日：2020-06-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyungrim Kim ,  Tae Yeon Kim ,  Imsang Lee ,  Kwang Woo Lee ,  Heeyeong Kim ,  Kwang Soo Shin

IPC: C07K14/34 ,  C07K14/245 ,  C12N1/20

CPC classification number: C07K14/34 ,  C07K14/245 ,  C12N1/205

Abstract: The present disclosure relates to an acetohydroxy acid synthase variant, a polynucleotide encoding the variant, a microorganism including the variant, and a method of producing L-isoleucine using the microorganism.

公开(公告)号：US10982244B2

公开(公告)日：2021-04-20

申请号：US16478286

申请日：2019-04-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Yon Kwon ,  Kwang Woo Lee ,  Lan Huh ,  Kyungrim Kim ,  Mina Baek ,  Seung-ju Son ,  Jaemin Lee

IPC: C12N1/21 ,  C12N9/04 ,  C12P13/12 ,  C12P13/06 ,  C12P13/08

Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing homoserine or a homoserine-derived L-amino acid using the same.

公开(公告)号：US12270061B2

公开(公告)日：2025-04-08

申请号：US17604896

申请日：2021-03-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Jin Choi ,  Imsang Lee ,  Heeyeong Kim ,  Byeong Soo Kim ,  Kwang Woo Lee

IPC: C12P13/14 ,  C12N9/00 ,  C12N15/10 ,  C12N15/77 ,  C12R1/15 ,  C40B40/02 ,  C40B40/10

Abstract: The present disclosure relates to a modified polypeptide of glutamine synthetase having enhanced activity and a method of producing L-glutamine using the same. Since production of L-glutamine may be increased by using the novel modified polypeptide without a decrease in a growth rate compared to wild-type strains having glutamine synthetase activity, the modified polypeptide may be widely used for mass production of L-glutamine.

公开(公告)号：US11667936B2

公开(公告)日：2023-06-06

申请号：US17938508

申请日：2022-10-06

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jaewon Jang ,  Kwang Woo Lee ,  Yong Uk Shin ,  Imsang Lee

IPC: C12P13/08 ,  C12N1/20 ,  C12N9/10 ,  C12P13/06 ,  C12P13/12 ,  C12R1/15

CPC classification number: C12P13/08 ,  C12N1/20 ,  C12N9/1025 ,  C12P13/06 ,  C12P13/12 ,  C12R2001/15 ,  C12Y203/03001

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.

公开(公告)号：US11293014B2

公开(公告)日：2022-04-05

申请号：US16484315

申请日：2019-04-09

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyungrim Kim ,  Hyo Jeong Byun ,  Kwang Woo Lee ,  Hyung Joon Kim ,  Yong Uk Shin ,  Jung Kee Lee

IPC: C12N9/26 ,  C12N1/20 ,  C12P13/04 ,  C12P13/06 ,  C12P13/08

Abstract: The present disclosure relates to a microorganism for producing an L-amino acid with enhanced activity of α-glucosidase and a method for producing an L-amino acid using the same. According to the present disclosure, the microorganism of the genus Corynebacterium producing an L-amino acid has enhanced activity of α-glucosidase, thereby improving L-amino acid production yield. Therefore, the microorganism may be very usefully used for L-amino acid production.

公开(公告)号：US11180784B2

公开(公告)日：2021-11-23

申请号：US16344205

申请日：2019-01-25

Applicant: CJ Cheiljedang Corporation

Inventor： Seung-ju Son ,  Byoung Hoon Yoon ,  Kwang Woo Lee ,  Seon Hye Kim ,  Hyo Jeong Byun ,  Jin Sook Chang ,  Hyung Joon Kim ,  Yong Uk Shin

IPC: C12P13/08 ,  C07K14/34

Abstract: A microorganism of the genus Corynebacterium producing L-amino acids, and a method of producing L-amino acids using the same.