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1.发明申请公开(公告)号：US20190292526A1
公开(公告)日：2019-09-26
申请号：US16426453
申请日：2019-05-30
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Lan Huh , Jun Ok Moon , Hyun Won Bae , Hyung Joon Kim , Sung Ki Song
Abstract: The present disclosure relates to a novel pyruvate dehydrogenase variant, a polynucleotide encoding the pyruvate dehydrogenase variant, a microorganism of the genus Corynebacterium producing L-amino acid, which includes the pyruvate dehydrogenase variant, and a method for producing an L-amino acid using the microorganism.
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2.发明申请MICROORGANISMS OF CORYNEBACTERIUM WHICH CAN UTILIZE XYLOSE AND METHOD FOR PRODUCING L-LYSINE USING SAME 审中-公开可以利用木糖醇的康乃馨的微生物和使用其生产L-赖氨酸的方法公开(公告)号：US20160040200A1
公开(公告)日：2016-02-11
申请号：US14923825
申请日：2015-10-27
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： So Yeon Rah , Lan Huh , Chang Gyeom Kim , Kwang Ho Lee , Jun Ok Moon , Kyung Han Lee , Jin Seok Sung , Hyung Joon Kim
CPC classification number: C12P13/08 , C12N9/1205 , C12N9/92 , C12Y207/01017 , C12Y503/01005 , Y02P20/52
Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
Abstract translation: 本发明涉及能够利用木糖的棒状杆菌的微生物和使用其的L-赖氨酸的制造方法。 更具体地，本发明涉及被修饰的棒状杆菌的微生物，其中引入木糖异构酶和木酮糖激酶的基因是木糖合成酶来表达木糖合酶。 本发明还涉及L-赖氨酸的制造方法，其特征在于，包括使用木糖作为碳源培养棒状杆菌的修饰微生物并从培养物中回收L-赖氨酸的步骤。
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公开(公告)号：US10526586B2
公开(公告)日：2020-01-07
申请号：US15557013
申请日：2016-03-15
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Lan Huh , Jun Ok Moon , Hyun Won Bae , Hyung Joon Kim , Sung Ki Song
Abstract: The present disclosure relates to a novel pyruvate dehydrogenase variant, a polynucleotide encoding the pyruvate dehydrogenase variant, a microorganism of the genus Corynebacterium producing L-amino acid, which includes the pyruvate dehydrogenase variant, and a method for producing an L-amino acid using the microorganism.
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4.发明申请MICROORGANISMS OF CORYNEBACTERIUM WHICH CAN UTILIZE XYLOSE AND METHOD FOR PRODUCING L-LYSINE USING SAME 有权可以利用木糖醇的康乃馨的微生物和使用其生产L-赖氨酸的方法公开(公告)号：US20140377816A1
公开(公告)日：2014-12-25
申请号：US14371653
申请日：2013-01-10
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： So Yeon Rah , Lan Huh , Chang Gyeom Kim , Kwang Ho Lee , Jun Ok Moon , Kyung Han Lee , Jin Seok Sung , Hyung Joon Kim
IPC: C12P13/08
CPC classification number: C12P13/08 , C12N9/1205 , C12N9/92 , C12Y207/01017 , C12Y503/01005 , Y02P20/52
Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
Abstract translation: 本发明涉及能够利用木糖的棒状杆菌的微生物和使用其的L-赖氨酸的制造方法。 更具体地，本发明涉及被修饰的棒状杆菌的微生物，其中引入木糖异构酶和木酮糖激酶的基因是木糖合成酶来表达木糖合酶。 本发明还涉及L-赖氨酸的制造方法，其特征在于，包括使用木糖作为碳源培养棒状杆菌的修饰微生物并从培养物中回收L-赖氨酸的步骤。
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公开(公告)号：US11236374B2
公开(公告)日：2022-02-01
申请号：US16483309
申请日：2019-05-21
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Hyo Jin Kim , Lan Huh , Sang Jo Lim , Hyun Ah Kim , Hyoung Joon Kim , Chang il Seo , Seung Bin Lee , Ji Sun Lee
Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20180037615A1
公开(公告)日：2018-02-08
申请号：US15508662
申请日：2015-09-04
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Lan Huh , Kwang Ho Lee , Hyung Joon Kim , Jun Ok Moon , Song-Gi Ryu
Abstract: The present disclosure relates to a novel modified RNA polymerase sigma factor A (SigA) polypeptide; a polynucleotide encoding the same; a microorganism containing the polypeptide; and a method for producing L-lysine using the microorganism.
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公开(公告)号：US09777282B2
公开(公告)日：2017-10-03
申请号：US15103147
申请日：2014-12-08
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Jun Ok Moon , Sang Hee Park , Lan Huh , Kwang Ho Lee
Abstract: A microorganism of the genus Corynebacterium with an improved ability to produce L-lysine in which a septum formation initiator protein is inactivated and a method for producing L-lysine using the microorganism.
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公开(公告)号：US11555213B2
公开(公告)日：2023-01-17
申请号：US17472028
申请日：2021-09-10
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Hyo Jin Kim , Lan Huh , Sang Jo Lim , Hyun Ah Kim , Hyoung Joon Kim , Chang il Seo , Seung Bin Lee , Ji Sun Lee
Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.
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公开(公告)号：US20220205003A1
公开(公告)日：2022-06-30
申请号：US17605648
申请日：2020-03-10
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Lan Huh , Nara Kwon , Chang Il Seo
Abstract: Provided are a microorganism having an enhanced L-histidine producing ability and a method of producing histidine using the same.
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公开(公告)号：US10982244B2
公开(公告)日：2021-04-20
申请号：US16478286
申请日：2019-04-10
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Su Yon Kwon , Kwang Woo Lee , Lan Huh , Kyungrim Kim , Mina Baek , Seung-ju Son , Jaemin Lee
Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing homoserine or a homoserine-derived L-amino acid using the same.
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