公开(公告)号：US11709129B2

公开(公告)日：2023-07-25

申请号：US17304928

申请日：2021-06-28

申请人： COR HEALTH, INC.

发明人： Robert G. Messerschmidt

IPC分类号： G01N21/27 ,  G01N21/35 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/026 ,  A61B5/145 ,  G01N21/33 ,  G01N21/65 ,  G01N33/49 ,  A61B5/20

CPC分类号： G01N21/27 ,  A61B5/0075 ,  A61B5/0261 ,  A61B5/1455 ,  A61B5/14507 ,  G01N21/33 ,  G01N21/35 ,  G01N21/65 ,  G01N33/49 ,  A61B5/208 ,  A61B2562/046 ,  G01N2201/068 ,  G01N2201/06113

摘要： A measurement apparatus comprises optical components arranged to provide parallel measurements of a biological sample. The parallel sample measurements provide improved accuracy with lower detection limit thresholds. The parallel measurements may comprise one or more of Raman spectroscopy measurements or infrared spectroscopy measurements. The parallel measurements can be combined with a light source. In many embodiments, the light source comprises one or more wavelengths corresponding to resonance frequencies of one or more molecules of the sample, such as wavelengths of ultraviolet light. The wavelengths of light corresponding to resonance frequencies can provide an increased signal to noise ratio. The parallel array optical configuration can be combined with wavelengths of light corresponding to resonance frequencies in order to provide increased measurement accuracy and detection of metabolites.

公开(公告)号：US11867613B2

公开(公告)日：2024-01-09

申请号：US17659702

申请日：2022-04-19

申请人： COR HEALTH, INC.

发明人： Robert G. Messerschmidt

IPC分类号： G01N21/25 ,  A61B5/151 ,  G01N33/49

CPC分类号： G01N21/255 ,  A61B5/151 ,  G01N33/49 ,  G01N2201/0221 ,  G01N2201/0636

摘要： A blood sample collector can be used to collect a blood sample from a subject. The blood sample collector can be placed in a receptacle of a spectrometer to measure spectral data from the blood sample while the blood sample separates. The container may comprise a window to allow light such as infrared light to pass through the container, with the blood sample at least partially separating within the container between spectral measurements, which can provide improved accuracy of the measurements and additional information regarding the sample. The container may comprise an elongate axis and the container configured for placement in the spectrometer receptacle with the elongate axis extending toward a vertical direction in order to improve gravimetric separation of the blood sample. The spectrometer can be configured to measure the blood sample at a plurality of heights along the sample as the sample separates.