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公开(公告)号:US12193677B2
公开(公告)日:2025-01-14
申请号:US17653269
申请日:2022-03-02
Applicant: Covidien LP
Inventor: Mark Philip Ashby , Ashok Nageswaran , Eric Mintz , Gaurav Girdhar , Ujwal Ramesh Jalgonkar , John Wainwright
IPC: A61B17/12
Abstract: Expandable devices for occluding bifurcation aneurysms are disclosed herein. Several of the embodiments are directed towards an expandable device comprising a mesh configured to be deployed at a treatment site including blood vessel bifurcation of a human patient so that the mesh extends across a neck of an aneurysm and prevents or limits blood flow through the mesh and into the aneurysm. The mesh can comprise one or more circumferentially discontinuous portions so that, when the device is deployed at the treatment site, the device does not substantially impede flow from a parent blood vessel to two or more branching blood vessels. Systems and methods for delivering an expandable device of the present technology are also disclosed herein.
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公开(公告)号:US20230036800A1
公开(公告)日:2023-02-02
申请号:US17818585
申请日:2022-08-09
Applicant: Covidien LP
Inventor: Xiaodong Ma , Min-Shyan Sheu , Lincoln Eramo , John Wainwright , Junwei Li
IPC: A61F2/82 , A61L31/02 , A61L31/16 , A61F2/90 , A61L31/10 , A61F2/06 , A61L31/14 , A61L33/00 , A61L33/06
Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
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公开(公告)号:US11369497B2
公开(公告)日:2022-06-28
申请号:US16586639
申请日:2019-09-27
Applicant: Covidien LP
Inventor: Xiaodong Ma , Min-Shyan Sheu , Lincoln Eramo , John Wainwright , Junwei Li
IPC: A61M60/165 , A61F2/82 , A61L31/02 , A61L31/16 , A61F2/90 , A61L31/10 , A61F2/06 , A61L31/14 , A61L33/00 , A61L33/06 , B05D1/18 , B05D3/14
Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
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公开(公告)号:US20210125525A1
公开(公告)日:2021-04-29
申请号:US16662901
申请日:2019-10-24
Applicant: Covidien LP
Inventor: Tejashri Kumar , Hoai Nguyen , John Wainwright , Evan Epstein , Gaurav Girdhar , Ujwal Jalgaonkar , Eric Mintz
Abstract: Vasculature models and associated systems and methods are disclosed herein. In some embodiments, the model comprises a tube including a lumen extending therethrough, a synthetic thrombus including a magnetic component, and a magnetized member. The thrombus is sized to be positioned within the lumen, and the magnetized member is positioned peripheral to the thrombus such that a radially outward force is exerted on the thrombus via the magnetized member. The tube may be part of a network of tubes that generally resemble human neurovasculature.
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公开(公告)号:US10806611B2
公开(公告)日:2020-10-20
申请号:US15478149
申请日:2017-04-03
Applicant: Covidien LP
Inventor: Anh Cam , Michael Losordo , Jianlu Ma , Luong Nguyen , Sanjay Shrivastava , John Wainwright , Xiaoling Zhao
Abstract: Vascular remodeling devices can include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchor the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.
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公开(公告)号:US20190125555A1
公开(公告)日:2019-05-02
申请号:US16173879
申请日:2018-10-29
Applicant: Covidien LP
Inventor: Xiaodong Ma , Min-Shyan Sheu , Lincoln Eramo , John Wainwright , Junwei Li
IPC: A61F2/82 , A61F2/06 , A61L31/16 , A61F2/90 , A61L31/10 , A61L31/02 , A61L33/06 , A61L31/14 , A61L33/00
Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
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公开(公告)号:US10226366B2
公开(公告)日:2019-03-12
申请号:US15404760
申请日:2017-01-12
Applicant: Covidien LP
Inventor: John Wainwright , Todd Mendelson , Kurt Haggstrom , Masoud Molaei , Victoria Schuman , Min-Shyan Sheu
Abstract: Medical devices that include a tubular member with a plurality of braided filaments, each filament crossing another of the filaments at a respective crossing point forming sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm, the pores have an average pore size that is less than or equal to about 500 microns when the tubular member is in an expanded state, the filaments possessing antithrombogenic surfaces to increase antithrombogenicity of the medical device with pores substantially free of webs formed by antithrombogenic material, such that fewer than 5% of the crossing points have webs formed by antithrombogenic material thereby permitting the pores to be substantially free of webs.
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公开(公告)号:US20170231789A1
公开(公告)日:2017-08-17
申请号:US15478149
申请日:2017-04-03
Applicant: Covidien LP
Inventor: Anh Cam , Michael Losordo , Jianlu Ma , Luong Nguyen , Sanjay Shrivastava , John Wainwright , Xiaoling Zhao
Abstract: Vascular remodeling devices can include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchor the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.
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9.
公开(公告)号:US09545301B2
公开(公告)日:2017-01-17
申请号:US14317587
申请日:2014-06-27
Applicant: Covidien LP
Inventor: John Wainwright , Todd Mendelson , Kurt Haggstrom , Masoud Molaei , Victoria Schuman , Min-Shyan Sheu
CPC classification number: A61F2/90 , A61F2/07 , A61F2/966 , A61F2002/072 , A61F2002/823 , A61F2002/9665 , A61F2210/0076 , A61F2230/0069 , A61F2250/0023 , A61F2250/0067 , A61F2310/00389 , B05D1/18 , B05D3/0272 , B05D3/04
Abstract: Coating methods and related devices are provided. Such devices can include stents. For example, the device can comprise a sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm. The device can also comprise an anti-thrombogenic coating distributed over at least a portion of the device such that the pores are substantially free of webs formed by the coating.
Abstract translation: 提供涂布方法和相关设备。 这样的装置可以包括支架。 例如,该装置可以包括侧壁和侧壁中的多个孔,其尺寸被设计成当管状构件定位时防止血液通过侧壁流入动脉瘤至足以导致动脉瘤血栓形成和愈合的程度 在血管中并且与动脉瘤相邻。 该装置还可以包含分布在装置的至少一部分上的抗血栓形成的涂层,使得孔基本上不含由涂层形成的网。
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10.
公开(公告)号:US20140277400A1
公开(公告)日:2014-09-18
申请号:US13844577
申请日:2013-03-15
Applicant: COVIDIEN LP
Inventor: John Wainwright , Todd Mendelson , Kurt Haggstrom , Xiaodong Ma , Masoud Molaei , John Muri , Anastasia Righter , Victoria Schuman , Min-Shyan Sheu
IPC: A61F2/07
CPC classification number: A61F2/07 , A61F2/90 , A61F2002/072 , A61F2002/823 , A61F2250/0067
Abstract: Coating methods and related devices are provided. Such devices can include stents. For example, the device can comprise a sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm. The device can also comprise an anti-thrombogenic coating distributed over at least a portion of the device such that the pores are substantially free of webs formed by the coating.
Abstract translation: 提供涂布方法和相关设备。 这样的装置可以包括支架。 例如,该装置可以包括侧壁和侧壁中的多个孔,其尺寸被设计成当管状构件定位时防止血液通过侧壁流入动脉瘤至足以导致动脉瘤血栓形成和愈合的程度 在血管中并且与动脉瘤相邻。 该装置还可以包含分布在装置的至少一部分上的抗血栓形成的涂层,使得孔基本上不含由涂层形成的网。
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