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公开(公告)号:US10935424B2
公开(公告)日:2021-03-02
申请号:US16563616
申请日:2019-09-06
Applicant: California Institute of Technology
Inventor: James K. Wallace
Abstract: A spectral measurement device capable of achieving a high level of diffraction efficiency by reducing the polarization sensitivity of the device. Many such embodiments are capable of achieving high diffraction efficiency by fixing the polarization of the incoming light to a fixed polarized state internal to the device, thereby allowing for the full spectrum of light to be captured and measured by the device.
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公开(公告)号:US20200080892A1
公开(公告)日:2020-03-12
申请号:US16563616
申请日:2019-09-06
Applicant: California Institute of Technology
Inventor: James K. Wallace
Abstract: A spectral measurement device capable of achieving a high level of diffraction efficiency by reducing the polarization sensitivity of the device. Many such embodiments are capable of achieving high diffraction efficiency by fixing the polarization of the incoming light to a fixed polarized state internal to the device, thereby allowing for the full spectrum of light to be captured and measured by the device.
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公开(公告)号:US10345572B2
公开(公告)日:2019-07-09
申请号:US15422241
申请日:2017-02-01
Applicant: California Institute of Technology
Inventor: Eugene Serabyn , Christian A. Lindensmith , James K. Wallace , Kurt M. Liewer , Jay L. Nadeau
Abstract: In situ investigation of microbial life in extreme environments can be carried out with microscopes capable of imaging 3-dimensional volumes and tracking particle motion. A lensless digital holographic microscope is disclosed that provides roughly 1.5 micron resolution in a compact, robust package suitable for remote deployment. High resolution is achieved by generating high numerical-aperture input beams with radial gradient-index rod lenses. The ability to detect and track prokaryotes was explored using bacterial strains of two different sizes. In the larger strain, a variety of motions were seen, while the smaller strain was used to demonstrate a detection capability down to micron scales.
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公开(公告)号:US20160131882A1
公开(公告)日:2016-05-12
申请号:US14939389
申请日:2015-11-12
Applicant: California Institute of Technology
Inventor: James K. Wallace , Kurt M. Liewer , Christian A. Lindensmith , Eugene Serabyn , Stephanie Rider , Emilio C. Graff
CPC classification number: G02B21/0056 , G02B21/0008 , G02B21/0072 , G02B21/008 , G02B21/18 , G03H1/0443 , G03H2001/005 , G03H2001/0445 , G03H2222/12 , G03H2222/13 , G03H2227/02
Abstract: A digital holographic microscope including a single mode fiber collimated light source which provides illumination for both the ‘science’ and ‘reference’ arms, a pair of microscope objectives located side-by side, and illuminated by the common beam, a relay lens whose center is between the two objectives, and a focal plane element where the interference pattern is measured. A lens-less digital holographic microscope and a reflective digital holographic microscope are also disclosed.
Abstract translation: 一种数字全息显微镜,包括单模光纤准直光源,为“科学”和“参考”臂提供照明,一对显微镜物镜并排定位并由共用光束照射,中心透镜的中心 在两个目标之间,并且测量干涉图案的焦平面元件。 还公开了无镜头数字全息显微镜和反射数字全息显微镜。
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公开(公告)号:US10054777B2
公开(公告)日:2018-08-21
申请号:US14939389
申请日:2015-11-12
Applicant: California Institute of Technology
Inventor: James K. Wallace , Kurt M. Liewer , Christian A. Lindensmith , Eugene Serabyn , Stephanie Rider , Emilio C. Graff
CPC classification number: G02B21/0056 , G02B21/0008 , G02B21/0072 , G02B21/008 , G02B21/18 , G03H1/0443 , G03H2001/005 , G03H2001/0445 , G03H2222/12 , G03H2222/13 , G03H2227/02
Abstract: A lens-less digital holographic microscope, a reflective digital holographic microscope, and a digital holographic microscope including a plurality of lenses. In one example, the digital holographic microscope includes a single mode fiber collimated light source which provides illumination for both the ‘science’ and ‘reference’ arms, a pair of microscope objectives located side-by side, and illuminated by the common beam, a relay lens whose center is between the two objectives, and a focal plane element where the interference pattern is measured.
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公开(公告)号:US20170219999A1
公开(公告)日:2017-08-03
申请号:US15422241
申请日:2017-02-01
Applicant: California Institute of Technology
Inventor: Eugene Serabyn , Christian A. Lindensmith , James K. Wallace , Kurt M. Liewer , Jay L. Nadeau
CPC classification number: G02B23/2484 , G02B3/0087 , G02B6/0005 , G02B6/0006 , G02B6/0008 , G02B21/365 , G02B23/2469 , G02B23/26 , G03H1/0443 , G03H1/0465 , G03H2001/005 , G03H2001/0436 , G03H2001/0445 , G03H2001/0469 , G03H2001/0471 , G03H2222/52 , G03H2223/17
Abstract: In situ investigation of microbial life in extreme environments can be carried out with microscopes capable of imaging 3-dimensional volumes and tracking particle motion. A lensless digital holographic microscope is disclosed that provides roughly 1.5 micron resolution in a compact, robust package suitable for remote deployment. High resolution is achieved by generating high numerical-aperture input beams with radial gradient-index rod lenses. The ability to detect and track prokaryotes was explored using bacterial strains of two different sizes. In the larger strain, a variety of motions were seen, while the smaller strain was used to demonstrate a detection capability down to micron scales.
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