公开(公告)号：US20210353439A1

公开(公告)日：2021-11-18

申请号：US17318821

申请日：2021-05-12

Applicant: California Institute of Technology ,  INSERM (Institut National de la Santé et de la Recherche Médicale) ,  CNRS-CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris

Inventor： Sumner L Norman ,  David Maresca ,  Vasileios Christopoulos ,  Mikhail Shapiro ,  Richard A. Andersen ,  Mickael Tanter ,  Charlie Demene

IPC: A61F2/70 ,  A61B8/06 ,  A61F4/00 ,  A61N1/08 ,  G16H30/40 ,  G06N20/00

Abstract: Methods and systems are provided for decoding movement intentions using functional ultrasound (fUS) imaging of the brain. In one example, decoding movement intentions include determining a memory phase of a cognitive state of the brain, the memory phase between a gaze fixation phase and movement execution phase, and determining one or more movement intentions including one or more of intended effector (e.g., hand, eye) and intended direction (e.g., right, left) according to a machine learning algorithm trained to classify one or more movement intentions simultaneously.

公开(公告)号：US20210100663A1

公开(公告)日：2021-04-08

申请号：US17121218

申请日：2020-12-14

Applicant: California Institute of Technology

Inventor： Carey Y. Zhang ,  Tyson Aflalo ,  Richard A. Andersen

IPC: A61F2/72 ,  G06F3/01 ,  G06N3/06 ,  G06N20/00 ,  A61F4/00

Abstract: In an embodiment, the invention relates to neural prosthetic devices in which control signals are based on the cognitive activity of the prosthetic user. The control signals may be used to control an array of external devices, such as prosthetics, computer systems, and speech synthesizers. Data obtained from a 4×4 mm patch of the posterial parietal cortex illustrated that a single neural recording array could decoded movements of a large extent of the body. Cognitive activity is functionally segregated between body parts.

公开(公告)号：US20140018882A1

公开(公告)日：2014-01-16

申请号：US13943227

申请日：2013-07-16

Applicant: California Institute of Technology

Inventor： Melanie Wilke ,  Igor Kagan ,  Richard A. Andersen

IPC: A61N1/36

CPC classification number: A61N1/36103 ,  A61B5/055 ,  A61B5/4064 ,  A61B2576/026 ,  A61N1/0529

Abstract: A method and system of compensating for a damaged brain node is disclosed. The damaged node is determined by techniques such as fMRI or neural recording. A healthy node that can compensate for the function of the damaged node is determined. A stimulating electrode is placed on at least one functioning node to bypass the activity from the damaged node to compensate for a missing node. The functioning node is then stimulated to compensate for the damaged node.

Abstract translation: 公开了补偿损伤脑节点的方法和系统。 受损节点由fMRI或神经记录等技术决定。 确定可以补偿损坏节点功能的健康节点。 刺激电极放置在至少一个功能节点上以绕过来自受损节点的活动以补偿丢失的节点。 然后激活功能节点以补偿损坏的节点。

公开(公告)号：US20180177619A1

公开(公告)日：2018-06-28

申请号：US15850625

申请日：2017-12-21

Applicant: California Institute of Technology

Inventor： Carey Y. Zhang ,  Tyson Aflalo ,  Richard A. Andersen

IPC: A61F2/72 ,  G06F3/01 ,  G06N3/06

CPC classification number: A61F2/72 ,  A61B5/04001 ,  A61B5/4851 ,  A61B5/6868 ,  A61B5/7264 ,  A61F4/00 ,  A61F2002/6827 ,  A61F2002/704 ,  G06F3/015 ,  G06N3/061

Abstract: In an embodiment, the invention relates to neural prosthetic devices in which control signals are based on the cognitive activity of the prosthetic user. The control signals may be used to control an array of external devices, such as prosthetics, computer systems, and speech synthesizers. Data obtained from a 4×4 mm patch of the posterial parietal cortex illustrated that a single neural recording array could decoded movements of a large extent of the body. Cognitive activity is functionally segregated between body parts.

公开(公告)号：US20240315665A1

公开(公告)日：2024-09-26

申请号：US18734823

申请日：2024-06-05

Applicant: California Institute of Technology ,  University of Southern California

Inventor： Sumner L. Norman ,  Claire Rabut ,  Whitney S. Griggs ,  Richard A. Andersen ,  Mikhail G. Shapiro ,  Charles Liu

IPC: A61B8/00 ,  A61F2/28

CPC classification number: A61B8/4209 ,  A61F2/2875

Abstract: A cranial implant that facilitates functional ultrasound imaging is disclosed. The example cranial implant replaces a section of a skull. The cranial implant in includes a support section shaped to replace a removed section of the skull. The implant includes a window of sonolucent material allowing functional ultrasound imaging through an ultrasound probe on the window. The window is shaped to allow access to a region of interest in the brain from the ultrasound probe.

公开(公告)号：US08831733B2

公开(公告)日：2014-09-09

申请号：US13943227

申请日：2013-07-16

Applicant: California Institute of Technology

Inventor： Melanie Wilke ,  Igor Kagan ,  Richard A. Andersen

IPC: A61N1/00 ,  A61N1/36

CPC classification number: A61N1/36103 ,  A61B5/055 ,  A61B5/4064 ,  A61B2576/026 ,  A61N1/0529

Abstract: A method and system of compensating for a damaged brain node is disclosed. The damaged node is determined by techniques such as fMRI or neural recording. A healthy node that can compensate for the function of the damaged node is determined. A stimulating electrode is placed on at least one functioning node to bypass the activity from the damaged node to compensate for a missing node. The functioning node is then stimulated to compensate for the damaged node.

Abstract translation: 公开了补偿损伤脑节点的方法和系统。 受损节点由fMRI或神经记录等技术决定。 确定可以补偿损坏节点功能的健康节点。 刺激电极放置在至少一个功能节点上以绕过来自受损节点的活动以补偿丢失的节点。 然后激活功能节点以补偿损坏的节点。