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公开(公告)号：US12295735B2
公开(公告)日：2025-05-13
申请号：US16705654
申请日：2019-12-06
Applicant: Cardiac Pacemakers, Inc.
Inventor： Deepa Mahajan , David L. Perschbacher , Sunipa Saha
Abstract: Systems and methods for detecting cardiac arrhythmia are discussed. An exemplary arrhythmia detection system can receive physiologic information of the patient, measure a first signal metric using a first portion of the received physiologic information, and determine an arrhythmia detection duration using a comparison between the measured first signal metric and a reference signal metric value. The system includes an arrhythmia detector to detect an AT episode using a second portion of the physiologic information corresponding to the determined arrhythmia detection duration.
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公开(公告)号：US20230173282A1
公开(公告)日：2023-06-08
申请号：US18073215
申请日：2022-12-01
Applicant: Cardiac Pacemakers, Inc.
Inventor： Abhijit Rajan , Deepa Mahajan , David L. Perschbacher
CPC classification number: A61N1/36585 , A61N1/025
Abstract: Systems and methods for detecting cardiac arrhythmias such as atrial tachyarrhythmia (AT) are discussed. An exemplary system includes an arrhythmia detector circuit that can receive physiologic information sensed from a patient over time, detect an arrhythmia onset when the physiologic information during a first time period satisfies an onset condition, and in response to the detected arrhythmia onset, detect an arrhythmia termination when the physiologic information during a second time period, subsequent to and longer than the first time period, satisfies an exit condition. An arrhythmia episode can be detected based on an arrhythmia duration between the detected onset and termination. The detected sustained arrhythmia episode can be provided to a user or a processor for further processing.
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公开(公告)号：US11504537B2
公开(公告)日：2022-11-22
申请号：US16263736
申请日：2019-01-31
Applicant: Cardiac Pacemakers, Inc.
Inventor： David L. Perschbacher , James O. Gilkerson , Sunipa Saha , Deepa Mahajan
IPC: A61N1/365 , A61B5/00 , A61N1/39 , A61B5/021 , A61B5/0245 , A61N1/37 , A61B5/349 , A61B5/0205 , A61N1/04 , A61B7/02 , A61B5/352
Abstract: Systems and methods for monitoring chronic over-pacing (COP) to the heart are discussed herein. In an embodiment, a system includes a receiver circuit to receive information about pacing rates of a plurality of paced heart beats, and a pacing analyzer circuit to generate a pacing rate distribution using pacing rates of the plurality of the paced heart beats. The pacing rate distribution includes a pacing rate histogram. The pacing analyzer circuit may recognize a morphological pattern from the pacing rate distribution, and detect a COP indication using the extracted feature. A programmer circuit adjusts one or more therapy parameters in response to the detected. COP indication.
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公开(公告)号：US11491337B2
公开(公告)日：2022-11-08
申请号：US16260947
申请日：2019-01-29
Applicant: Cardiac Pacemakers, Inc.
Inventor： Deepa Mahajan , David L. Perschbacher , Sunipa Saha
Abstract: Systems and methods for managing machine-generated alert notifications of medical events detected from one or more patients are described herein. An embodiment of a data management system may receive an adjudication of a medical event episode including an episode characterization. A storage unit stores an association between one or more episode characterizations and corresponding detection algorithms for detecting a medical event having respective episode characterizations. An episode management circuit may detect from a subsequent episode, using the stored association, a medical event having an episode characterization of at least one medical event episode presented for adjudication, and schedule presenting at least a portion of the subsequent episode based on the detection.
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公开(公告)号：US11480561B2
公开(公告)日：2022-10-25
申请号：US16518621
申请日：2019-07-22
Applicant: Cardiac Pacemakers, Inc.
Inventor： Gezheng Wen , Qi An , Pramodsingh Hirasingh Thakur , Deepa Mahajan
IPC: A61B5/0205 , G01N33/50
Abstract: Systems, devices, and methods for monitoring and assessing immunotherapy toxicity are discussed. An exemplary system receives physiologic information from a patient using an ambulatory medical device. In response to an immunotherapy such as CAR T-cell therapy, the system determines a toxicity indication using the received physiologic information. A therapy can be initiated or adjusted using the toxicity indication.
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Patent Agency Ranking
公开(公告)号：US11357441B2
公开(公告)日：2022-06-14
申请号：US16260817
申请日：2019-01-29
Applicant: Cardiac Pacemakers, Inc.
Inventor： David L. Perschbacher , Sunipa Saha , Deepa Mahajan
IPC: A61N1/37 , A61B5/361 , A61N1/05 , A61B5/00 , G16H40/63 , G16H15/00 , G16H50/30 , A61B5/363 , A61N1/39 , A61N1/08 , A61N1/365 , A61B5/0205 , A61B5/024 , A61B5/145 , A61B5/11 , A61N1/362 , A61B5/0215 , A61B5/0245 , A61B5/08 , A61B5/283 , A61B5/316
Abstract: Systems and methods for managing cardiac arrhythmias are discussed. A data management system receives a first detection algorithm including a detection criterion for detecting a cardiac arrhythmia. An arrhythmia detector detects arrhythmia episodes from a physiologic signal using a second detection algorithm that is different from and has a higher sensitivity for detecting the cardiac arrhythmia than the first detection algorithm. The arrhythmia detector assigns a detection indicator to each of the detected arrhythmia episodes. The detection indicator indicates a likelihood that the detected arrhythmia episode satisfies the detection criterion of the first detection algorithm. The system prioritizes the detected arrhythmia episodes according to the assigned detection indicators, and outputs the arrhythmia episodes to a user or a process according to the episode prioritization.
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公开(公告)号：US11298068B2
公开(公告)日：2022-04-12
申请号：US16705732
申请日：2019-12-06
Applicant: Cardiac Pacemakers, Inc.
Inventor： David L. Perschbacher , Deepa Mahajan , Sunipa Saha
Abstract: Systems and methods for detecting cardiac arrhythmias such as atrial tachyarrhythmia (AT) are discussed. An exemplary system includes a ventricular beat analyzer circuit to detect ventricular beats and assess ventricular activity, such as to evaluate a ventricular rate stability. The system includes an arrhythmia detector circuit to detect respective AT indications in distinct time periods using portions of received physiologic information during the distinct time periods. A control circuit can monitor the ventricular beats on a beat-by-beat basis, in response to the detected ventricular beats satisfying an instability condition, trigger AT detections during the distinct time periods and withhold AT detection in a subsequent time period if no AT is detected in the present time period. An AT characteristic may be generated using the detected AT indications. A therapy may be delivered in accordance with the AT characteristic.
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公开(公告)号：US11052255B2
公开(公告)日：2021-07-06
申请号：US16256746
申请日：2019-01-24
Applicant: Cardiac Pacemakers, Inc.
Inventor： Amy Jean Brisben , David J. Ternes , Allan Charles Shuros , Deepa Mahajan , David L. Perschbacher
Abstract: Systems and methods for pacing cardiac conductive tissue are described. A medical system includes an electrostimulation circuit to generate His-bundle pacing (HBP) pulses. A sensing circuit senses a physiologic signal, and detect a local His-bundle activation discrete from a pacing artifact of the HBP pulse. A control circuit verifies capture status in response to the HBP pulses. Based on the capture status, the control circuit determines one or more pacing thresholds including a selective HBP threshold representing a threshold strength to capture only the His bundle but not the local myocardium, and a non-selective HBP threshold representing a threshold strength to capture both the His bundle and the local myocardium. The electrostimulation circuit may deliver HBP pulses based on the selective and non-selective HBP thresholds.
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公开(公告)号：US20200375490A1
公开(公告)日：2020-12-03
申请号：US16886260
申请日：2020-05-28
Applicant: Cardiac Pacemakers, Inc.
Inventor： Keith L. Herrmann , Krzysztof Z. Siejko , Deepa Mahajan , Gezheng Wen
IPC: A61B5/0464 , A61B5/0452 , A61B5/0456 , G16H10/60 , G16H30/20 , G16H50/70
Abstract: Systems and methods for classifying a cardiac arrhythmia are discussed. An exemplary system includes a correlator circuit to generate autocorrelation sequences using information of cardiac activity of a subject, including signal segments taken from a cardiac signal at respective elapsed time with respect to reference time. The correlator circuit can generate a correlation image using the autocorrelation sequences. The correlation image may be constructed by stacking the autocorrelation sequences according to the elapsed time of signal segments. An arrhythmia classifier circuit can classify the cardiac activity of the subject as one of arrhythmia types using the correlation image.
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公开(公告)号：US20200179692A1
公开(公告)日：2020-06-11
申请号：US16691171
申请日：2019-11-21
Applicant: Cardiac Pacemakers, Inc.
Inventor： David J. Ternes , Deepa Mahajan , Keith L. Herrmann
Abstract: Systems and methods for pacing cardiac conductive tissue are described. An exemplary system includes an electrostimulation circuit that may generate HBP pulses to stimulate patient physiologic conduction pathway, such as a His bundle or a bundle branch. The system includes an arrhythmia detector to detect an atrial tachyarrhythmia (AT) with intermittent ventricular conduction. A control circuit may sense ventricular activation and, in response to the detected AT indication, determine or update a His-bundle pacing (HBP) configuration. The HBP may be recursively updated on a beat-by-beat basis using the sensed ventricular activation. The electrostimulation circuit may deliver HBP according to the determined or adjusted HBP configuration to regularize ventricular rate during AT.
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