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公开(公告)号：US20240008821A1
公开(公告)日：2024-01-11
申请号：US18218504
申请日：2023-07-05
IPC分类号： A61B5/00 , A61B5/0245 , A61B5/352
CPC分类号： A61B5/7275 , A61B5/6847 , A61B5/0245 , A61B5/352
摘要： Systems and methods for detecting and classifying premature ventricular contractions (PVCs) are discussed. An exemplary system includes a sensor circuit to sense a cardiac signal of a subject, and a processor circuit to detect heartbeats from the cardiac signal and detect a PVC under a first detection mode or a different second detection mode. The first detection mode includes identifying a PVC candidate of a particular type using cardiac intervals or signal amplitudes of the detected heartbeats, and classifying the identified PVC candidate as a PVC singleton or a pattern of multiple consecutive PVCs using signal features including morphology features of the sensed cardiac signal. The second detection mode includes detecting PVC of the particular type using the cardiac intervals or the signal amplitudes of the detected heartbeats. The first detection mode can be transitioned to the second detection mode in response to a mode-switching trigger event.
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公开(公告)号：US11832968B2
公开(公告)日：2023-12-05
申请号：US15478652
申请日：2017-04-04
发明人： David L. Perschbacher , Deepa Mahajan , Krzysztof Z. Siejko , Keith L Herrmann , Jonathan Walter Krueger
CPC分类号： A61B5/7221 , A61B5/02405 , A61B5/076 , A61B5/361 , A61B5/364 , A61B5/4836 , A61B5/686 , A61B5/7203 , A61B5/746 , A61N1/3621 , A61N1/3627 , A61N1/3704
摘要： Systems and methods for detecting an arrhythmic event and storing physiological information associated with the detected arrhythmic event are described. A system may include a first detector to detect an arrhythmic event from a physiological signal sensed from a subject, and generate a confidence indicator indicating a confidence level of the detection of the arrhythmic event. If the confidence indicator indicates a relatively high confidence of arrhythmia detection, the system may provide the detected arrhythmic event to a first process for storing the detected arrhythmic event or generating an alert. If the confidence indicator indicates a relatively low confidence of arrhythmia detection, the system may provide the detected arrhythmic event to at least a second process including confirming or rejecting the detected arrhythmic event.
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公开(公告)号：US11826152B2
公开(公告)日：2023-11-28
申请号：US16886260
申请日：2020-05-28
摘要： Systems and methods for classifying a cardiac arrhythmia are discussed. An exemplary system includes a correlator circuit to generate autocorrelation sequences using information of cardiac activity of a subject, including signal segments taken from a cardiac signal at respective elapsed time with respect to reference time. The correlator circuit can generate a correlation image using the autocorrelation sequences. The correlation image may be constructed by stacking the autocorrelation sequences according to the elapsed time of signal segments. An arrhythmia classifier circuit can classify the cardiac activity of the subject as one of arrhythmia types using the correlation image.
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公开(公告)号：US20230122366A1
公开(公告)日：2023-04-20
申请号：US18084345
申请日：2022-12-19
发明人： Pramodsingh Hirasingh Thakur , Jason Humphrey , David J. Ternes , Qi An , Krzysztof Z. Siejko , Michael James Dufresne , Yinghong Yu
摘要： Systems and methods for managing heart failure are described. The system receives physiological information including a first HS signal corresponding to paced ventricular contractions and a second HS signal corresponding to intrinsic ventricular contractions. The system detects worsening heart failure (WHF) using the received physiological information. A signal analyzer circuit can generate a paced HS metric from the first HS signal and a sensed HS metric from the second HS signal, and determine a concordance indicator between the paced and the sensed HS metrics. In response to the detected WHF, the system can use the concordance indicator to generate a therapy adjustment indicator for adjusting electrostimulation therapy, or a worsening cardiac contractility indicator indicating the detected WHF is attributed to degrading myocardial contractility.
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5.发明授权公开(公告)号：US11497921B2
公开(公告)日：2022-11-15
申请号：US16681103
申请日：2019-11-12
发明人： Stephen J. Hahn , Krzysztof Z. Siejko , William J. Linder , Keith R. Maile , Amy Jean Brisben , Keith L. Herrmann , Brendan E. Koop , Benjamin J. Haasl
IPC分类号： A61N1/372 , A61N1/365 , A61N1/375 , A61N1/39 , A61B5/00 , A61B5/349 , A61N1/362 , A61N1/368 , A61B5/352 , A61B5/363
摘要： Systems, methods and implantable devices configured to provide cardiac resynchronization therapy and/or bradycardia pacing therapy. A first device located in the heart of the patient is configured to receive a communication from a second device and deliver a pacing therapy in response to or in accordance with the received communication. A second device located elsewhere is configured to determine an atrial event has occurred and communicate to the first device to trigger the pacing therapy. The second device may be configured for sensing the atrial event by the use of vector selection and atrial event windowing, among other enhancements. Exception cases are discussed and handled as well.
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公开(公告)号：US11464983B2
公开(公告)日：2022-10-11
申请号：US16366899
申请日：2019-03-27
发明人： Stephen J. Hahn , Pramodsingh Hirasingh Thakur , Qi An , Viktoria A. Averina , Krzysztof Z. Siejko , Ramesh Wariar
摘要： This document discusses, among other things, systems and methods to generate a first pacing waveform during a first pacing period and a second pacing waveform during a second pacing period, to alternate first and second pacing periods to provide pacing-based hypertension therapy to a heart of a patient to reduce patient blood pressure, to receive information indicative of patient metabolic demand, and to determine an adjusted pacing-based hypertension therapy parameter using the received information indicative of patient metabolic demand, wherein the first pacing waveform has a first atrioventricular (AV) delay and the second pacing waveform has a second AV delay longer than the first AV delay.
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公开(公告)号：US20200324121A1
公开(公告)日：2020-10-15
申请号：US16845762
申请日：2020-04-10
发明人： Yinghong Yu , Krzysztof Z. Siejko , Qi An
IPC分类号： A61N1/365
摘要： This document discusses, among other things, systems and methods to determine a response between received cardiac electrical information from a subject, such as a time of a P wave, and received cardiac acceleration information of the subject, such as a time of a first heart sound (S1) or a second heart sound (S2), across a set of stimulation signals provided to the subject at different AVD intervals, and determining one or more cardiac resynchronization therapy (CRT) parameters using an inflection point of the determined response.
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公开(公告)号：US10780278B2
公开(公告)日：2020-09-22
申请号：US15684366
申请日：2017-08-23
摘要： Methods, systems and devices for providing cardiac resynchronization therapy (CRT) to a patient using a leadless cardiac pacemaker (LCP) and an extracardiac device (ED). The LCP is configured to deliver pacing therapy at a pacing interval. Illustratively, the ED may be configured to analyze the cardiac cycle including a portion preceding the pacing therapy delivery for one or several cardiac cycles, and determine whether an interval from the P-wave to the pace therapy in the cardiac cycle(s) is in a desired range. In an example, if the P-wave to pace interval is outside the desired range, the ED communicates to the LCP to adjust the pacing interval.
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公开(公告)号：US10729909B2
公开(公告)日：2020-08-04
申请号：US15598614
申请日：2017-05-18
发明人： Jeffrey E. Stahmann , Krzysztof Z. Siejko , Carlos Haro , Abhilash Patangay , Gerrard M. Carlson , Andres Belalcazar
IPC分类号： A61B5/02 , A61B5/024 , A61B5/00 , A61N1/365 , A61B5/11 , A61B7/04 , A61B5/021 , A61B5/053 , A61B5/08
摘要： A system and method to sense heart sounds with one or more implantable medical devices according to one or more signal processing parameters. The method alters one or more of the parameters as a function of one or more physiologic triggering events. The method then senses heart sounds with the one or more implantable medical devices according to at least the one or more altered signal processing parameters.
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10.发明授权公开(公告)号：US10512784B2
公开(公告)日：2019-12-24
申请号：US15633517
申请日：2017-06-26
发明人： Stephen J. Hahn , Krzysztof Z. Siejko , William J. Linder , Keith R. Maile , Amy Jean Brisben , Keith L. Herrmann , Brendan E. Koop , Benjamin J. Haasl
IPC分类号： A61N1/365 , A61N1/375 , A61B5/0452 , A61N1/372 , A61N1/39 , A61B5/00 , A61N1/362 , A61N1/368 , A61B5/0456 , A61B5/0464
摘要： Systems, methods and implantable devices configured to provide cardiac resynchronization therapy and/or bradycardia pacing therapy. A first device located in the heart of the patient is configured to receive a communication from a second device and deliver a pacing therapy in response to or in accordance with the received communication. A second device located elsewhere is configured to determine an atrial event has occurred and communicate to the first device to trigger the pacing therapy. The second device may be configured for sensing the atrial event by the use of vector selection and atrial event windowing, among other enhancements. Exception cases are discussed and handled as well.
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