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公开(公告)号：US07317947B2
公开(公告)日：2008-01-08
申请号：US10835548
申请日：2004-04-29
IPC分类号： A61N1/378
CPC分类号： A61N1/3787
摘要： The invention is directed to a recharging system and associated techniques to recharge an implantable medical device (IMD). In particular, a recharging system according to the invention comprises a headset having an energy delivery module that delivers energy to a power source of an IMD implanted on or within the cranium of a patient. The energy delivery module may comprise a coil for inductive transfer of energy to the power source. The headset may be configured for placement over the head of the patient, and may further only partially cover the top of the head. The energy delivery module may be adjustably coupled to the headset. In some embodiments, the position of the energy delivery module may be adjusted along three or four axes, including a rotational axis, allowing the coil to be placed over an IMD located at any of a variety of locations on or within the cranium.
摘要翻译： 本发明涉及一种再充电系统和相关技术以对可植入医疗装置（IMD）进行再充电。 特别地，根据本发明的再充电系统包括具有能量递送模块的头戴式耳机，所述能量递送模块将能量传递到植入在患者的颅骨上或内部的IMD的动力源。 能量传递模块可以包括用于将能量感应地传递到电源的线圈。 耳机可以被配置为放置在患者的头部上，并且还可以仅部分地覆盖头部的顶部。 能量传递模块可以可调整地耦合到耳机。 在一些实施例中，能量输送模块的位置可以沿着三个或四个轴线（包括旋转轴线）进行调整，允许线圈放置在位于颅骨上或颅内的各种位置中的任何位置上的IMD上。
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公开(公告)号：US08620453B2
公开(公告)日：2013-12-31
申请号：US12954563
申请日：2010-11-24
IPC分类号： A61N1/05
CPC分类号： A61N1/08 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N1/086 , A61N1/36071
摘要： A medical lead is provided for use in a pulse stimulation system of the type which includes a pulse generator for producing electrical stimulation therapy. The lead comprises an elongate insulating body and at least one electrical conductor within the insulating body. The conductor has a proximal end configured to be electrically coupled to the pulse generator and has a DC resistance in the range of 375-2000 ohms. At least one distal electrode is coupled to the conductor.
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公开(公告)号：US08457744B2
公开(公告)日：2013-06-04
申请号：US10730877
申请日：2003-12-09
IPC分类号： A61N1/08
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： Components of an implantable medical device are arranged to facilitate a low-profile housing. A circuit board within the housing carries integrated circuits and discrete components. In some embodiments, the integrated circuits and discrete components are located on first and second opposing surfaces of the circuit board, respectively. In some embodiments, the implantable medical device is implanted on a cranium of a patient and the housing is concave such that it substantially conforms to the cranium. In such embodiments, the integrated circuits and/or discrete components can be arranged on the circuit board according to height to better conform to the concavity of the housing. In some embodiments, the implantable medical device includes a telemetry coil that is positioned within the housing such that it occupies space that cannot be practically occupied by the circuit board.
摘要翻译： 可植入医疗装置的部件被布置成便于小型外壳。 外壳内的电路板承载集成电路和分立元件。 在一些实施例中，集成电路和分立元件分别位于电路板的第一和第二相对表面上。 在一些实施例中，将可植入医疗装置植入患者的颅骨上，并且所述外壳是凹形的，使得其基本上符合颅骨。 在这样的实施例中，集成电路和/或分立组件可以根据高度布置在电路板上，以更好地符合壳体的凹面。 在一些实施例中，可植入医疗装置包括位于壳体内的遥测线圈，使其占据不能被电路板实际占据的空间。
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公开(公告)号：US20100049277A1
公开(公告)日：2010-02-25
申请号：US12611504
申请日：2009-11-03
CPC分类号： A61N1/0504 , A61N1/0456 , A61N1/0476 , A61N1/0492 , A61N1/0502 , A61N1/36071 , A61N1/3756
摘要： The disclosure describes an implantable neurostimulator device for delivery of neurostimulation to treat head, neck, or facial pain or tension, including pain or tension caused by occipital neuralgia. The device may be a neurostimulation device having a miniaturized housing with a low profile that permits subcutaneous implantation at a stimulation site directly adjacent a neuralgic region at the back of the neck of a patient. For example, the device may be subcutaneously implanted at the back of the neck of a patient to relieve symptoms of occipital neuralgia.
摘要翻译： 本公开描述了用于递送神经刺激以治疗头部，颈部或面部疼痛或张力的可植入神经刺激器装置，包括由枕骨神经痛引起的疼痛或张力。 该装置可以是具有小型化的壳体的神经刺激装置，其具有允许在紧邻患者颈部后方的神经痛区域的刺激部位皮下植入。 例如，该装置可以皮下植入患者颈部的后部以减轻枕骨神经痛的症状。
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公开(公告)号：US07647121B2
公开(公告)日：2010-01-12
申请号：US11687440
申请日：2007-03-16
IPC分类号： A61N1/36
CPC分类号： A61B5/053 , A61B5/04012 , A61B5/0402 , A61B5/103 , A61N1/36071 , A61N1/36521 , A61N1/37247 , G06F19/00 , G16H40/63
摘要： Techniques for selectably providing either constant voltage or constant current stimulation are described. A programming device provides a user interface by which a user selects either constant voltage or constant current stimulation, and selects either a voltage or current amplitude based on the selected stimulation mode. The programming device configures a medical device to provide the selected mode of stimulation at the selected amplitude. For example, when a medical device has constant voltage stimulation circuitry, e.g., circuitry including a voltage source, and the user selects constant current stimulation, the programming device configures the medical device to adjust the voltage amplitude based on a measured impedance to provide substantially constant current amplitude.
摘要翻译： 描述了可选择地提供恒定电压或恒定电流刺激的技术。 编程设备提供用户界面，用户通过该界面用户选择恒定电压或恒定电流刺激，并且基于所选择的刺激模式选择电压或电流幅度。 编程设备配置医疗设备以在所选择的幅度提供所选择的刺激模式。 例如，当医疗设备具有恒定电压刺激电路（例如，包括电压源的电路）并且用户选择恒定电流刺激时，编程设备配置医疗设备以基于测量的阻抗来调整电压幅度以提供基本上恒定的 电流幅度。
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公开(公告)号：US07596408B2
公开(公告)日：2009-09-29
申请号：US10837319
申请日：2004-04-30
申请人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
发明人： Ruchika Singhal , Darren A. Janzig , Carl D. Wahlstrand , Robert M. Skime , Paulette C. Olson , Erik R. Scott , James E. Randall
IPC分类号： A61N1/02
CPC分类号： A61N1/3754 , A61B5/076 , A61B2560/04 , A61L31/16 , A61L2300/404 , A61N1/3605 , A61N1/375
摘要： An implantable medical device with anti-infection agent. The implantable medical device may be configured for placement in the head of a patient and for monitoring or treatment of the brain. The implantable medical device may have a housing or it may have a housing and a member for providing a smooth interface between the device and the adjacent tissue. The anti-infection agent may be provided on or impregnated in the housing or the member. In some embodiments, the device includes a single module while in other embodiments a plurality of modules are coupled to provide a smaller profile. In some embodiments the implantable medical device may include both anti-infection and lubricious materials.
摘要翻译： 具有抗感染剂的可植入医疗器械。 可植入医疗装置可被配置用于放置在患者的头部并用于监测或治疗大脑。 可植入医疗装置可以具有壳体，或者其可以具有壳体和用于在装置和相邻组织之间提供平滑界面的构件。 抗感染剂可以设置在或浸渍在壳体或构件中。 在一些实施例中，设备包括单个模块，而在其它实施例中，多个模块被耦合以提供较小的轮廓。 在一些实施例中，可植入医疗装置可以包括抗感染和光滑材料。
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公开(公告)号：US07596399B2
公开(公告)日：2009-09-29
申请号：US10835527
申请日：2004-04-29
CPC分类号： A61B5/6864 , A61B5/107 , A61B5/686 , A61B5/6868
摘要： In general, the invention is directed to strategies pertaining to implantation of an implantable medical device between a scalp and a skull of the patient. The invention pertains to collection of data such as data pertaining to the skull of the patient, the scalp of the patient, the vascular structure or neurological structures in the head of the patient, and the like. The data may be in the form of images, such as images generated by X-ray, magnetic resonance imaging, CT-scan and fluoroscopy. A surgeon can use the collected data to determine, for example, whether the patient is a candidate for a cranial implantation, whether the patient's skull and scalp can support the implantation, what configuration of device should be implanted, where the device should be implanted, and how the surgical incisions should be made.
摘要翻译： 通常，本发明涉及关于在头皮和患者头骨之间植入可植入医疗装置的策略。 本发明涉及诸如患者头骨，患者头皮，患者头部的血管结构或神经结构等数据的收集等。 数据可以是图像的形式，例如通过X射线产生的图像，磁共振成像，CT扫描和荧光透视。 外科医生可以使用收集的数据来确定例如患者是颅骨植入的候选者，患者的颅骨和头皮是否能够支撑植入，应植入装置的哪些配置，植入装置的位置， 以及如何做外科切口。
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8.发明授权Reducing relative intermodule motion in a modular implantable medical device 失效在模块化可植入医疗设备中减少相对模块间运动公开(公告)号：US07392089B2
公开(公告)日：2008-06-24
申请号：US10731881
申请日：2003-12-09
IPC分类号： A61N1/36
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： A modular implantable medical device includes a plurality of modules that are at least partially encapsulated by an overmold. The modules may be connected by coupling modules, which may be flexible to provide for one or more degrees of relative intermodular motion. The overmold may also be flexible. In order to reduce relative intermodule motion to acceptable direction and/or ranges, the overmold may include one or more motion reduction elements.
摘要翻译： 模块化可植入医疗装置包括至少部分地由包覆成型包封的多个模块。 模块可以通过耦合模块连接，耦合模块可以是柔性的，以提供一个或多个相对的模块间运动程度。 包覆成型也可以是柔性的。 为了将相对模块间运动减小到可接受的方向和/或范围，包覆模具可以包括一个或多个运动减少元件。
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公开(公告)号：US07263401B2
公开(公告)日：2007-08-28
申请号：US10835233
申请日：2004-04-29
摘要： An implantable medical device (IMD) including a nonhermetic battery is described. The IMD includes components and a power source module that includes the nonhermetic battery. The IMD also includes a barrier to substantially impede movement of substances from the nonhermetic battery to the components. The barrier may include a hermetic feedthrough, a gel, a polymer, or a solid electrolyte within the nonhermetic battery, and a seal member. The barrier may also be a material that encapsulates the nonhermetic battery and a getter within the IMD. In some embodiments, the IMD comprises a modular IMD including an interconnect member. In that case, the barrier may include a material that fills at least a portion of a void defined by the interconnect member. A length and a cross-sectional area of the interconnect member may also act as a barrier.
摘要翻译： 描述了包括非密封电池的可植入医疗装置（IMD）。 IMD包括组件和包含非密封电池的电源模块。 IMD还包括阻止物质从非密封电池移动到部件的屏障。 阻挡层可以包括非密封电池内的密封馈通，凝胶，聚合物或固体电解质，以及密封构件。 屏障还可以是在IMD内封装非密封电池和吸气剂的材料。 在一些实施例中，IMD包括包括互连构件的模块化IMD。 在这种情况下，阻挡层可以包括填充由互连构件限定的空隙的至少一部分的材料。 互连构件的长度和横截面积也可以用作屏障。
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公开(公告)号：US07242982B2
公开(公告)日：2007-07-10
申请号：US10730873
申请日：2003-12-09
IPC分类号： A61N1/36
CPC分类号： A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要： A modular implantable medical device permits implantable medical devices to have a smaller profile in order to better fit into locations within the human body. A modular implantable medical device separates various functional components of the implantable medical device into a set of interconnected modules. This distributed architecture of a modular implantable medical device may permit the device footprint to be distributed over a larger area while making the profile smaller, and may permit the overall shape of the implantable medical device to better match the body location into which it is to be implanted. An overmold integrates the modules of a modular implantable medical device into a single structure. In some embodiments the overmold is flexible and provides a biocompatible interface from the component modules and the patient, while restraining potentially harmful intermodule motion.
摘要翻译： 模块化可植入医疗装置允许植入式医疗装置具有更小的外形，以便更好地适应人体内的位置。 模块化可植入医疗装置将可植入医疗装置的各种功能部件分离成一组互连的模块。 模块化可植入医疗设备的这种分布式架构可以允许设备占地面积分布在更大的区域上，同时使轮廓更小，并且可以允许可植入医疗设备的整体形状更好地匹配要被植入的医疗设备的身体位置 植入。 包覆模具将模块化可植入医疗设备的模块集成到单个结构中。 在一些实施方案中，包覆成型是柔性的并且提供来自组件模块和患者的生物相容性界面，同时限制潜在有害的模块间运动。
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