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6 条记录 (耗时 0.018 秒)

    COLON DISEASE TARGETS AND USES THEREOF
    5.
    发明申请
    COLON DISEASE TARGETS AND USES THEREOF 审中-公开

    公开(公告)号：US20200325189A1

    公开(公告)日：2020-10-15

    申请号：US16744571

    申请日：2020-01-16

    申请人： Celera Corporation

    发明人： Bruno DOMON ,  Aiqun LI ,  Tao HE ,  Ian MCCAFFREY

    IPC分类号： C07K14/47 ,  G01N33/574 ,  C07K16/18 ,  C07K16/30 ,  C12N15/113 ,  C12Q1/6886

    摘要： The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon.

    COLON DISEASE TARGETS AND USES THEREOF
    6.
    发明申请
    COLON DISEASE TARGETS AND USES THEREOF 审中-公开
    结肠疾病目标及其用途

    公开(公告)号：US20140178391A1

    公开(公告)日：2014-06-26

    申请号：US14057434

    申请日：2013-10-18

    申请人： Celera Corporation

    发明人： Bruno DOMON ,  Aiqun LI ,  Tao HE ,  Ian MCCAFFREY

    IPC分类号： C07K16/18 ,  G01N33/574

    CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K39/00 ,  C07K16/18 ,  C07K16/3046 ,  C07K2317/734 ,  C12N15/113 ,  C12N2310/14 ,  C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/158 ,  G01N33/57419

    摘要： The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon.

    摘要翻译： 本发明提供了诊断和检测与结肠相关疾病的方法。 本发明提供在结肠疾病（CC​​AT）中差异表达的一种或多种蛋白质或其片段，肽或核酸分子，并且抗体结合CCAT。 本发明提供CCAT用作调节CCAT活性的筛选剂的靶标。 此外，本发明提供了治疗与结肠相关疾病的方法。