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    OCCLUSION MEMBER AND TENSIONER APPARATUS AND METHODS OF THEIR USE FOR SEALING A VASCULAR PUNCTURE
    1.
    发明申请
    OCCLUSION MEMBER AND TENSIONER APPARATUS AND METHODS OF THEIR USE FOR SEALING A VASCULAR PUNCTURE 有权
    OCCLUSION会员和张力器装置及其用于密封血管的使用方法

    公开(公告)号：US20080058864A1

    公开(公告)日：2008-03-06

    申请号：US11929762

    申请日：2007-10-30

    申请人： Celso Bagaoisan ,  Juan Domingo ,  Nicanor Domingo ,  Farhad Khosravi ,  Suresh Pai

    发明人： Celso Bagaoisan ,  Juan Domingo ,  Nicanor Domingo ,  Farhad Khosravi ,  Suresh Pai

    IPC分类号： A61B17/03 ,  A61M25/10

    CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00557 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61M25/10182 ,  A61M25/10187 ,  A61M2025/0681

    摘要： Apparatus for sealing a puncture includes an elongate occlusion member having a balloon attached to distal ends of telescoping inner and outer members. A housing on the proximal end of the outer member includes a piston coupled to the inner member and slidable within a chamber communicating with a fluid reservoir. A switch on the housing is actuated to direct fluid from the reservoir through the outer member into the balloon to expand the balloon and into the chamber to move the piston and pull the inner member, shortening the balloon as it expands. During use, the distal end of the occlusion member is introduced into a puncture communicating with a vessel until the collapsed balloon is disposed within the vessel. The balloon is expanded, and a tensioner is connected to the housing to apply a proximal force holding the balloon against the vessel wall to seal the puncture.

    摘要翻译： 用于密封穿刺的装置包括具有附接到伸缩的内部和外部构件的远端的气囊的细长闭塞构件。 外部构件的近端上的壳体包括联接到内部构件并可在与流体储存器连通的腔室内滑动的活塞。 启动壳体上的开关以将流体从储存器引导通过外部构件进入气囊，以使气囊膨胀并进入腔室中，以移动活塞并拉动内部构件，从而在气囊膨胀时缩短气囊。 在使用期间，将阻塞构件的远端引入到与血管连通的穿刺件中，直到将收缩的气囊设置在血管内。 气囊膨胀，并且张紧器连接到壳体以施加将气囊保持抵靠血管壁的近侧力以密封穿刺。

    APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE
    2.
    发明申请
    APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE 有权
    用于密封血管内窥镜的装置和方法

    公开(公告)号：US20080082122A1

    公开(公告)日：2008-04-03

    申请号：US11854534

    申请日：2007-09-12

    申请人： Farhad Khosravi ,  Suresh Pai ,  Celso Bagaoisan ,  Scott Sershen ,  Marlon Moreno ,  Juan Domingo

    发明人： Farhad Khosravi ,  Suresh Pai ,  Celso Bagaoisan ,  Scott Sershen ,  Marlon Moreno ,  Juan Domingo

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0057 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61B2017/00654

    摘要： An apparatus for sealing a puncture through tissue to a vessel includes an elongate occlusion member including an expandable member, a cartridge carried on the occlusion member, and a sealant carried within the cartridge. The cartridge includes an outer member and a pusher member within the outer member. The sealant is disposed within the outer member adjacent the expandable member distal to the pusher member. During use, the occlusion member is introduced into a puncture until the expandable member and the sealant extend from the puncture into the vessel. The expandable member is expanded, and withdrawn until the expanded expandable member contacts the vessel wall, thereby withdrawing the sealant back into the puncture. The outer member is withdrawn to expose the sealant within the puncture, while the pusher member prevents removal of the sealant, and then the cartridge, occlusion member, and pusher member are successively removed.

    摘要翻译： 用于将通过组织的穿刺密封到容器的装置包括包括可扩张构件的细长阻塞构件，承载在闭塞构件上的药筒和在药筒内承载的密封剂。 该盒在外部构件内包括外部构件和推动构件。 密封剂设置在外部构件中，邻近可推动构件远离推动构件。 在使用期间，将阻塞构件引入穿刺中，直到可膨胀构件和密封剂从穿刺件延伸到容器中。 可膨胀构件被膨胀并且被抽出直到膨胀的可膨胀构件接触血管壁，从而将密封剂抽回到穿刺中。 取出外部构件以在穿刺中露出密封剂，同时推动器构件防止密封剂的移除，然后连续地移除盒，遮挡构件和推动构件。

    Apparatus and methods for delivering sealing materials during a percutaneous procedure to facilitate hemostasis
    4.
    发明申请
    Apparatus and methods for delivering sealing materials during a percutaneous procedure to facilitate hemostasis 审中-公开
    用于在经皮操作过程中输送密封材料以便于止血的装置和方法

    公开(公告)号：US20070060950A1

    公开(公告)日：2007-03-15

    申请号：US10975205

    申请日：2004-10-27

    申请人： Farhad Khosravi ,  Suresh Pai ,  Celso Bagaoisan ,  Scott Sershen

    发明人： Farhad Khosravi ,  Suresh Pai ,  Celso Bagaoisan ,  Scott Sershen

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00004 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61B2090/062

    摘要： An apparatus for sealing a puncture extending through tissue to a blood vessel includes a guidewire including an expandable tamp, a retaining sheath for covering the tamp, and a delivery sheath including a primary lumen for receiving the guidewire therethrough and a secondary lumen for delivering sealing compound into the puncture. The guidewire is advanced into the puncture with the tamp in a contracted condition, the tamp is expanded within the vessel after retracting the retaining sheath, and the guidewire is retracted to seal the puncture from the vessel. The delivery sheath is advanced over the guidewire, and sealing compound is introduced into the puncture through the delivery sheath. After introducing the sealing compound, the delivery sheath is removed, and an introducer sheath is advanced over the guidewire to provide access to perform a medical procedure via the vessel after removing the guidewire.

    摘要翻译： 用于将延伸穿过组织的穿刺密封到血管的装置包括：导丝，包括可膨胀的夯，用于覆盖夯的保持护套;以及输送护套，其包括用于接收导丝的主腔，以及用于输送密封化合物的第二内腔 进入穿刺。 导丝在收缩状态下用夯实进入穿刺中，在缩回保持护套之后，在容器内膨胀，并且引导线缩回以密封穿孔。 输送护套在引导线上前进，并且密封化合物通过输送护套引入穿刺。 在引入密封化合物之后，移除输送护套，并且引导器护套在引导线上前进，以在移除引导线之后提供通过血管执行医疗程序的通路。

    Apparatus and methods for sealing a vascular puncture
    5.
    发明申请
    Apparatus and methods for sealing a vascular puncture 有权

    公开(公告)号：US20060100664A1

    公开(公告)日：2006-05-11

    申请号：US10982385

    申请日：2004-11-05

    申请人： Suresh Pai ,  Celso Bagaoisan ,  Farhad Khosravi

    发明人： Suresh Pai ,  Celso Bagaoisan ,  Farhad Khosravi

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61B2017/00672

    摘要： Apparatus for sealing a puncture through tissue to a blood vessel includes a cartridge including a proximal end, a distal end sized for insertion into a puncture, and a lumen extending therebetween. A bioabsorbable plug is disposed within the lumen adjacent the distal end, and an anchoring element is disposed within the lumen proximal to the plug. A pusher member is disposed within the lumen for deploying the plug and anchoring element out the distal end of the cartridge. The plug may be formed from lyophilized hydrogel and the anchoring element may be formed from air-dried hydrogel, the anchoring element hydrating slower than the plug when exposed to an aqueous environment. During use, the plug and anchoring element are delivered into the puncture, the plug is cinched against the vessel wall. Protrusions on the anchoring element engage tissue surrounding the puncture to prevent proximal movement of the plug.

    Apparatus and methods for delivering sealing materials during a percutaneous procedure to facilitate hemostasis
    7.
    发明申请
    Apparatus and methods for delivering sealing materials during a percutaneous procedure to facilitate hemostasis 审中-公开
    用于在经皮手术过程中输送密封材料以便于止血的装置和方法

    公开(公告)号：US20050149117A1

    公开(公告)日：2005-07-07

    申请号：US10745946

    申请日：2003-12-24

    申请人： Farhad Khosravi ,  Celso Bagaoisan ,  Suresh Pai ,  Scott Sershen

    发明人： Farhad Khosravi ,  Celso Bagaoisan ,  Suresh Pai ,  Scott Sershen

    IPC分类号： A61B17/00 ,  A61B17/08 ,  A61M5/178

    CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/0065

    摘要： Apparatus and methods are provided for sealing a puncture extending through tissue to a blood vessel. A delivery sheath is introduced-into the puncture, and a sealing compound, e.g., precursor polymers that mix to create a hydrogel, is introduced through the delivery sheath into the puncture. The delivery sheath is then removed, an introducer sheath is advanced through the puncture into the vessel, and instruments are introduced through the introducer sheath into the vessel to perform a medical procedure. After completing the procedure, the introducer sheath is withdrawn. The sealing compound may expand into the puncture and/or tissue recoil of the surrounding tissue may cause the sealing compound to at least partially occlude the puncture to facilitate sealing and/or hemostasis.

    摘要翻译： 提供了用于将延伸穿过组织的穿刺密封到血管的装置和方法。 将输送护套引入穿刺中，并且通过输送护套将密封化合物（例如混合以产生水凝胶的前体聚合物）引入穿刺中。 然后移出输送鞘，引导器护套穿过穿刺进入血管，并且将器械通过导引器鞘导入血管以执行医疗程序。 完成该程序后，引导器护套被取出。 密封化合物可能膨胀到周围组织的穿刺和/或组织反冲中，可能导致密封化合物至少部分地阻塞穿刺以便于密封和/或止血。

    Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture
    9.
    发明授权
    Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture 有权
    闭塞成员和张紧器设备及其用于密封血管穿刺的方法

    公开(公告)号：US07985240B2

    公开(公告)日：2011-07-26

    申请号：US11929762

    申请日：2007-10-30

    申请人： Celso J. Bagaoisan ,  Juan Domingo ,  Nicanor Domingo ,  Farhad Khosravi ,  Suresh S. Pai

    发明人： Celso J. Bagaoisan ,  Juan Domingo ,  Nicanor Domingo ,  Farhad Khosravi ,  Suresh S. Pai

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00557 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61M25/10182 ,  A61M25/10187 ,  A61M2025/0681

    摘要： Apparatus for sealing a puncture includes an elongate occlusion member having a balloon attached to distal ends of telescoping inner and outer members. A housing on the proximal end of the outer member includes a piston coupled to the inner member and slidable within a chamber communicating with a fluid reservoir. A switch on the housing is actuated to direct fluid from the reservoir through the outer member into the balloon to expand the balloon and into the chamber to move the piston and pull the inner member, shortening the balloon as it expands. During use, the distal end of the occlusion member is introduced into a puncture communicating with a vessel until the collapsed balloon is disposed within the vessel. The balloon is expanded, and a tensioner is connected to the housing to apply a proximal force holding the balloon against the vessel wall to seal the puncture.

    摘要翻译： 用于密封穿刺的装置包括具有附接到伸缩的内部和外部构件的远端的气囊的细长闭塞构件。 外部构件的近端上的壳体包括联接到内部构件并可在与流体储存器连通的腔室内滑动的活塞。 启动壳体上的开关以将流体从储存器引导通过外部构件进入气囊，以使气囊膨胀并进入腔室中，以移动活塞并拉动内部构件，从而在气囊膨胀时缩短气囊。 在使用期间，将阻塞构件的远端引入到与血管连通的穿刺件中，直到将收缩的气囊设置在血管内。 气囊膨胀，并且张紧器连接到壳体以施加将气囊保持抵靠血管壁的近侧力以密封穿刺。

    Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture
    10.
    发明授权
    Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture 有权
    闭塞成员和张紧器设备及其用于密封血管穿刺的方法

    公开(公告)号：US07316704B2

    公开(公告)日：2008-01-08

    申请号：US10806927

    申请日：2004-03-22

    申请人： Celso J. Bagaoisan ,  Juan Domingo ,  Nicanor Domingo ,  Farhad Khosravi ,  Suresh S. Pai

    发明人： Celso J. Bagaoisan ,  Juan Domingo ,  Nicanor Domingo ,  Farhad Khosravi ,  Suresh S. Pai

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B2017/00557 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61M25/10182 ,  A61M25/10187 ,  A61M2025/0681

    摘要： Apparatus for sealing a puncture includes an elongate occlusion member having a balloon attached to distal ends of telescoping inner and outer members. A housing on the proximal end of the outer member includes a piston coupled to the inner member and slidable within a chamber communicating with a fluid reservoir. A switch on the housing is actuated to direct fluid from the reservoir through the outer member into the balloon to expand the balloon and into the chamber to move the piston and pull the inner member, shortening the balloon as it expands. During use, the distal end of the occlusion member is introduced into a puncture communicating with a vessel until the collapsed balloon is disposed within the vessel. The balloon is expanded, and a tensioner is connected to the housing to apply a proximal force holding the balloon against the vessel wall to seal the puncture.

    摘要翻译： 用于密封穿刺的装置包括具有附接到伸缩的内部和外部构件的远端的气囊的细长闭塞构件。 外部构件的近端上的壳体包括联接到内部构件并可在与流体储存器连通的腔室内滑动的活塞。 启动壳体上的开关以将流体从储存器引导通过外部构件进入气囊，以使气囊膨胀并进入腔室中，以移动活塞并拉动内部构件，从而在气囊膨胀时缩短气囊。 在使用期间，将阻塞构件的远端引入到与血管连通的穿刺件中，直到将收缩的气囊设置在血管内。 气囊膨胀，并且张紧器连接到壳体以施加将气囊保持抵靠血管壁的近侧力以密封穿刺。