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公开(公告)号：US20090275815A1
公开(公告)日：2009-11-05
申请号：US12503376
申请日：2009-07-15
IPC分类号： A61B5/1473
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/14865 , A61B5/6848 , A61B2560/0252
摘要： An in-vivo sensor assembly includes an assembly body having a body proximal end and a body distal end, a plurality of sensor elements including at least an analyte sensor element containing an enzyme that is a substrate of the analyte to be measured, a reference sensor element and a temperature sensor element disposed at or near the body distal end wherein the at least an analyte sensor element and the reference sensor element are exposed to the sample fluid and the temperature sensor is capable of measuring the temperature of and adjacent to the analyte sensor element, and an electrical coupling means disposed at the body proximal end and configured to couple to the at least an analytical sensor element, the reference sensor element and the temperature sensor element.
摘要翻译： 体内传感器组件包括具有身体近端和身体远端的组件主体，多个传感器元件至少包括分析物传感器元件，所述分析物传感器元件包含作为待测量分析物的基底的酶，参考传感器 元件和设置在身体远端处或附近的温度传感器元件，其中至少分析物传感器元件和参考传感器元件暴露于样品流体，并且温度传感器能够测量分析物传感器的温度并与其相邻 元件和设置在身体近端处并且被配置为耦合到至少一个分析传感器元件，参考传感器元件和温度传感器元件的电耦合装置。
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公开(公告)号：US20100102264A1
公开(公告)日：2010-04-29
申请号：US12258475
申请日：2008-10-27
CPC分类号： F16K25/005 , F16K11/0743 , Y10T137/86558 , Y10T137/86638
摘要： A shear valve assembly includes a stationary valve manifold having a manifold planar surface containing a plurality of manifold input ports and one or more manifold output ports, a movable valve switch having a switch planar surface in slidable, interactive contact with the manifold planar surface forming an interactive contact junction, the switch planar surface having a fluid switching channel capable of connecting one of the plurality of manifold input ports with one of the one or more manifold output ports, a surface modifying component disposed at the interactive contact junction that provides a period of extended useful life of the manifold planar surface and the switch planar surface beyond the useful life of pre-lubricated interactive contact junction, a drive shaft connected to the valve switch, and a valve housing supporting the stationary valve manifold, the movable valve switch, and the drive shaft.
摘要翻译： 剪切阀组件包括具有包含多个歧管输入端口和一个或多个歧管输出端口的歧管平面的固定阀歧管，可移动阀开关，其具有与歧管平面的可滑动的交互式接触的开关平面， 所述开关平面表面具有能够将所述多个歧管输入端口中的一个与所述一个或多个歧管输出端口中的一个连接的流体切换通道，设置在所述交互式接触接点处的表面修饰部件， 在预润滑的交互式接触接头的使用寿命之后延长歧管平面和开关平面的使用寿命，连接到阀开关的驱动轴和支撑固定阀歧管的阀壳，可动阀开关和 驱动轴。
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公开(公告)号：US20090240121A1
公开(公告)日：2009-09-24
申请号：US12052985
申请日：2008-03-21
申请人： Charles Bickoff
发明人： Charles Bickoff
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/14865 , A61B5/6848 , A61M25/0014 , A61M2025/0079 , A61M2025/0681
摘要： An intravascular sensor assembly insertable into an intravenous catheter, the sensor assembly includes a sheath having a sheath proximal end and a sheath distal end wherein an outer diameter of the sheath is sized to be substantially equal to the outer diameter of an insertion needle of the intravenous catheter, a hub sealingly connected to the sheath proximal end, the hub adapted for removably coupling to the intravenous catheter, a sensor disposed within the sheath, the sensor having a sensor shank with a shank distal end and a shank proximal end, a plurality of sensor elements including a working electrode with a reagent matrix disposed thereon, the reagent matrix comprising an enzyme capable of catalyzing a reaction involving a substrate for the enzyme and a reference electrode, the plurality of sensor elements disposed adjacent the shank distal end, a plurality of connector pads disposed at the shank proximal end where the plurality of connector pads are contained within the hub and the plurality of sensor elements are exposed adjacent the sheath distal end, and a plurality of elongated conductive elements where each of the plurality of conductive elements electrically couples one of the plurality of sensor elements to one of the plurality of connector pads, and a cable electrically coupled to the plurality of connector pads.
摘要翻译： 可插入到静脉内导管中的血管内传感器组件，传感器组件包括具有护套近端和护套远端的护套，其中护套的外径尺寸设计成基本上等于静脉内插入针的外径 导管，密封地连接到护套近端的毂，毂适于可移除地联接到静脉导管，设置在护套内的传感器，传感器具有带柄远端和柄近端的传感器柄，多个 传感器元件，包括其上设置有试剂基质的工作电极，所述试剂基质包含能够催化涉及所述酶的底物和参考电极的反应的酶，所述多个传感器元件邻近所述柄末端设置，多个 设置在柄部近端的连接器焊盘，其中多个连接器焊盘包含在毂a内 并且所述多个传感器元件暴露在所述护套远端附近，以及多个细长导电元件，其中所述多个导电元件中的每一个将所述多个传感器元件中的一个电耦合到所述多个连接器焊盘中的一个，以及电缆 电耦合到多个连接器焊盘。
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公开(公告)号：US5482389A
公开(公告)日：1996-01-09
申请号：US344864
申请日：1994-11-25
申请人： Charles Bickoff , Dominic P. Emello
发明人： Charles Bickoff , Dominic P. Emello
CPC分类号： B26D1/085 , B26D5/22 , B41J11/70 , Y10T83/8748
摘要： A paper cutting device of an electronic printer which derives its motive power from the drive source operating the paper feed mechanism of the printer. The paper feed mechanism has a one-way clutch coupled to the paper feed drive shaft which locks on to the shaft when feeding print media in the forward direction and over runs when the paper feed drive source rotates opposed to the print media driving direction. A second one-way clutch is coupled to the cutter drive shaft and positively engages the cutter mechanism when the paper feed drive is operated in the reverse non-feeding direction. It over runs when print media is being fed. The cutting mechanism is driven through its one-way clutch to a couple eccentric crank. The crank pushes a linear guided cutter blade by means of an articulated link which engages the blade. The paper is registered against the front edge of a slot in the blade guide and the blade is forced through the restrained media. The blade is then positively retracted and its home position is sensed by an optical sensor which signals the control electronics that the cutting cycle has been completed. The home position is detented to allow the cutting mechanism to be opened without loosing its home reference position.
摘要翻译： 一种电子打印机的切纸装置，其从驱动源获得其动力，操作打印机的送纸机构。 供纸机构具有联接到供纸驱动轴的单向离合器，当供纸驱动源与打印介质驱动方向相反地旋转时，当向前方向供给打印介质时，供纸驱动轴锁定在轴上。 第二单向离合器联接到切割器驱动轴，并且当供纸驱动器在相反的非进给方向上操作时，第二单向离合器与切割机构正确接合。 当打印介质进纸时，它会运行。 切割机构通过单向离合器驱动到一对偏心曲柄。 曲柄通过与叶片接合的铰接连杆推动线性引导切割刀片。 纸张抵靠刀片引导件中的槽的前边缘，并且刀片被强制通过约束介质。 然后刀片被正向缩回，并且其原始位置由光学传感器感测到，该传感器向控制电子装置指示切割循环已经完成。 起始位置是允许切割机构打开而不会丢失其原始位置。
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公开(公告)号：US4964832A
公开(公告)日：1990-10-23
申请号：US385827
申请日：1989-07-27
申请人： Charles Bickoff
发明人： Charles Bickoff
CPC分类号： A63H3/14 , A63H3/52 , Y10S446/901 , Y10T24/27 , Y10T24/2708 , Y10T428/24017
摘要： This invention relates to the design of a modular puppet construction system which allows the user to achieve a broadly variable configuration, thereby permitting the user to add and remove modular body parts, features, clothing, other articles of usage, and control elements. The body and attachable parts may preferably be fabricated from a loop type material. The attachable parts and control elements may have hook type material permanently affixed to allow universal placement on the loop fabricated elements. The hook type material may also advantageously be a free standing part in a back to back configuration and used as an intermediate element to attach two loop fabricated parts. Additionally, elements not fabricated from loop or hook type materials may be affixed to the loop or hook type material to facilitate use. Moreover, the attachment interface may be in the form of an articulating or hingeable device which is surfaced with hook "VELCRO"-like material which when positioned between two physical elements of the puppet allow many degrees of movement or control of the attached modular parts. Additionally, the hook or loop type fastener may be affixed to control elements such as push rods and string controls to allow the fastening of such control elements to the modular puppet assembly. This modular arrangement thereby allows the toy to be configured as or converted between a stuffed toy, simple and advanced form of hand puppet, and a marionette.
摘要翻译： 本发明涉及一种模块化木偶构造系统的设计，其允许用户实现广泛可变的构造，从而允许用户添加和移除模块化身体部位，特征，衣服，其他使用制品和控制元件。 主体和可附接部件可以优选地由环形材料制成。 可连接部件和控制元件可以具有永久固定的钩型材料，以允许通常放置在环形构件上。 钩型材料还可以有利地是背对背构造的独立部分，并且用作连接两个环制造部件的中间元件。 此外，不由环或钩型材料制成的元件可以固定到环或钩型材料以便于使用。 此外，附接界面可以是铰接或铰链式装置的形式，其以“VELCRO”形钩状材料表面浮雕，当被放置在木偶的两个物理元件之间时允许附着的模块化部件的许多程度的移动或控制。 此外，钩或环型紧固件可以固定到诸如推杆和串控制的控制元件，以允许将这些控制元件紧固到模块化木偶组件。 因此，这种模块化装置允许玩具被配置为或者在填充玩具，简单而高级的手傀儡形式和牵线木偶之间进行转换。
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公开(公告)号：US4786047A
公开(公告)日：1988-11-22
申请号：US903403
申请日：1986-09-02
CPC分类号： B65H29/20 , B65H2701/1912
摘要： Apparatus for conveying a sheet of paper from a power feeder to an exit point including a frame for guiding the moving sheet along a preselected path and including a flexible member between the feeder and the exit point for normally guiding the sheet along the preselected path, the flexible member allowing the sheet to buckle in a direction normal to the plane of and away from the preselected path in response to an obstruction.
摘要翻译： 用于将一张纸从供电器输送到出口点的设备，该出口点包括用于沿着预选路径引导移动片材的框架，并且在馈送器和出口点之间包括柔性构件，用于沿预选路径正常引导片材， 柔性构件允许片材响应于障碍物沿垂直于预定路径的平面并远离预选路径的方向弯曲。
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7.发明授权Automated point of care detection system including complete sample processing capabilities 失效自动点护理检测系统，包括完整的样品处理能力公开(公告)号：US06656428B1
公开(公告)日：2003-12-02
申请号：US09632343
申请日：2000-08-03
申请人： David D. Clark , Jeffrey W. Steaffens , John Dorson , Ian Wells , Alan J. Fujii , James E. Maynard , James Baker , John Zeis , Charles Bickoff , Richard D. McEachern , Kunio Kohga , Andrew Ghusson , John C. Balsavich, Jr.
发明人： David D. Clark , Jeffrey W. Steaffens , John Dorson , Ian Wells , Alan J. Fujii , James E. Maynard , James Baker , John Zeis , Charles Bickoff , Richard D. McEachern , Kunio Kohga , Andrew Ghusson , John C. Balsavich, Jr.
IPC分类号： G01N2100
CPC分类号： B01L3/502 , B01L2200/16 , B01L2300/0672 , B01L2400/0478 , B01L2400/0644 , G01N35/00 , G01N35/1002 , G01N2035/0436 , G01N2035/0443 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： The present invention relates to cost effective analytical instruments for determining the presence or amount of an analyte in a sample. The analytical instruments utilize an assay cartridge which has a sample receiving port and a rotatable carousel containing a plurality of reagent wells. Each reagent well includes a piston element for delivery of reagent to a test surface. The instrument is capable of indexing the assay cartridge to deliver sample and reagents to a test surface in a predetermined and flexibile manner, thus providing an assay protocol which is specific to the type of sample under analysis. The invention also relates to components, features, disposables, reagent delivery systems, accessories, and methods for using such instruments. Appropriate applications include infectious disease testing, cancer detection and monitoring, therapeutic drug level monitoring, allergy testing, environmental testing, food testing, diagnostic testing of human and veterinary samples, and off-line process testing.
摘要翻译： 本发明涉及用于确定样品中分析物的存在或量的成本有效的分析仪器。 分析仪器使用具有样品接收端口和包含多个试剂阱的可旋转转盘的测定盒。 每个试剂井都包括用于将试剂输送到测试表面的活塞元件。 该仪器能够对分析盒进行分度，以将样品和试剂以预定和灵活的方式递送到测试表面，从而提供对所分析样品类型特异性的测定方案。 本发明还涉及用于使用这些仪器的组件，特征，一次性用品，试剂递送系统，附件和方法。 适当的应用包括传染病测试，癌症检测和监测，治疗药物水平监测，过敏测试，环境测试，食品测试，人类和兽医样品的诊断测试以及离线过程测试。
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公开(公告)号：US5520403A
公开(公告)日：1996-05-28
申请号：US411953
申请日：1995-03-28
CPC分类号： A61G5/08 , A61G5/0825 , A61G5/10 , A61G5/1054 , A61G5/1059 , A61G7/10 , A61G2200/34 , A61G7/1032 , Y10S297/04 , Y10S414/134
摘要： A wheelchair having a set of features which facilitate transfering a patient to an alternative surface and raising the chair to an alternative seating height. The first of these features enables each of the handwheels to be independently pivoted rearward by raising its related arm rest. The motion of the wheel is over centering and its rearward position is determined by a brake pad which engages its respective handwheel. The rearward position of the handwheel is such as to clear the rear of the seat. The forward position is determined with the arm rest in the normal down position and latched to the frame. The second feature is a lifting mechanism for raising the patient to the level of an alternative surface such as a bed. The third feature has the seat surface fabricated from a moveable belt which laterally transports the patient to the alternative surface. The wheelchair also has an embodiment which allows folding for easy transport.
摘要翻译： 轮椅具有一组特征，便于将患者转移到替代表面并将椅子升高到另外的座椅高度。 这些特征中的第一个使得每个手轮可以通过提升其相关的扶手来独立地向后枢转。 车轮的运动超过定心，其后方位置由与其相应的手轮接合的制动衬块确定。 手轮的向后位置可以清除座椅的后部。 前臂位置由扶手定位在正常向下位置并锁定在框架上。 第二特征是用于将患者升高到诸如床的替代表面的水平的提升机构。 第三特征具有由可移动带制造的座面，其将患者侧向输送到替代表面。 轮椅还具有允许折叠以便于运输的实施例。
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公开(公告)号：US3960256A
公开(公告)日：1976-06-01
申请号：US516513
申请日：1974-10-21
IPC分类号： B41J2/24 , B41J25/308 , B41J3/04
CPC分类号： B41J25/3082 , B41J2/24 , B41J25/308
摘要： Apparatus for a matrix printer by which the distance between the printhead and the paper being printed upon may be adjusted. The printhead is secured to a carriage whose position may be adjusted with respect to the paper by rotating a pair of bearings that are rotatably mounted in the carriage and centrally located around a stationary shaft.
摘要翻译： 用于矩阵式打印机的装置可通过该装置调节打印头和被打印的纸张之间的距离。 打印头通过旋转一对可旋转地安装在滑架中并且位于固定轴周围的中心的轴承而被固定到可以相对于纸张调整其位置的滑架。
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