High throughput method for measurement of physicochemical values
    1.
    发明授权
    High throughput method for measurement of physicochemical values 失效
    用于测量物理化学值的高通量方法

    公开(公告)号:US06562627B1

    公开(公告)日:2003-05-13

    申请号:US09471854

    申请日:1999-12-23

    IPC分类号: G01N3002

    摘要: Methods are provided for determining a dissociation constant for each one of at least a portion of a set of compounds. The methods include contacting a solution of the set of compounds with a membrane mimetic surface exhibiting a non-specific compound-dependent affinity for at least the portion of the compounds. A parameter dependent on the non-specific affinity of the surface for each one of at least the portion of the set of compounds in the test solution is measured and used to calculate the dissociation constant.

    摘要翻译: 提供了用于确定一组化合物的至少一部分中的每一个的解离常数的方法。 所述方法包括使该组化合物的溶液与至少部分化合物表现出非特异性化合物依赖性亲和力的膜模拟表面接触。 测量取决于测试溶液中至少部分化合物的至少一部分中每一个表面的非特异性亲和力的参数,并用于计算解离常数。