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公开(公告)号:US20060275825A1
公开(公告)日:2006-12-07
申请号:US11403128
申请日:2006-04-12
CPC分类号: G01N33/5432 , G01N33/54373 , G01N33/551 , G01N33/92
摘要: The invention provides compositions and methods for detection of interaction of molecules.
摘要翻译: 本发明提供了用于检测分子相互作用的组合物和方法。
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公开(公告)号:US20090192049A1
公开(公告)日:2009-07-30
申请号:US12414048
申请日:2009-03-30
CPC分类号: G01N33/5432 , G01N33/54373 , G01N33/551 , G01N33/92
摘要: The invention provides compositions and methods for detection of interaction of molecules.
摘要翻译: 本发明提供了用于检测分子相互作用的组合物和方法。
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公开(公告)号:US07429492B2
公开(公告)日:2008-09-30
申请号:US11566818
申请日:2006-12-05
申请人: Bo Lin , Gangadhar Jogikalmath , Timothy Smith , Kurt Albertson , Christine Genick , Lance Laing
发明人: Bo Lin , Gangadhar Jogikalmath , Timothy Smith , Kurt Albertson , Christine Genick , Lance Laing
IPC分类号: G01N33/543
CPC分类号: G01N21/41 , G01N21/253 , G01N21/75 , G01N2021/7779 , Y10S435/81 , Y10S436/805 , Y10S436/809 , Y10S436/815
摘要: The invention provides compositions and methods of detecting binding of molecules to a biosensor. Compositions of the invention comprise a multiwell plate with an integrated biosensor and a membrane.
摘要翻译: 本发明提供检测分子与生物传感器结合的组合物和方法。 本发明的组合物包括具有集成的生物传感器和膜的多孔板。
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公开(公告)号:US20080020480A1
公开(公告)日:2008-01-24
申请号:US11566818
申请日:2006-12-05
申请人: Bo Lin , Gangadhar Jogikalmath , Timothy Smith , Kurt Albertson , Christine Genick , Lance Laing
发明人: Bo Lin , Gangadhar Jogikalmath , Timothy Smith , Kurt Albertson , Christine Genick , Lance Laing
CPC分类号: G01N21/41 , G01N21/253 , G01N21/75 , G01N2021/7779 , Y10S435/81 , Y10S436/805 , Y10S436/809 , Y10S436/815
摘要: The invention provides compositions and methods of detecting binding of molecules to a biosensor. Compositions of the invention comprise a multiwell plate with an integrated biosensor and a membrane.
摘要翻译: 本发明提供检测分子与生物传感器结合的组合物和方法。 本发明的组合物包括具有集成的生物传感器和膜的多孔板。
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公开(公告)号:US20090130703A1
公开(公告)日:2009-05-21
申请号:US12335393
申请日:2008-12-15
IPC分类号: C12Q1/02
CPC分类号: G01N21/63 , C40B30/04 , C40B30/10 , G01N21/4788 , G01N21/7743 , G01N33/54373
摘要: Methods are provided to detect changes in cells without the use of detection labels.
摘要翻译: 提供方法来检测细胞的变化,而不使用检测标记。
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">6.Method for Employing a Biosensor to Detect Small Molecules ("Fragments") that Bind Directly to Immobilized Protein Targets 审中-公开
标题翻译: 使用生物传感器检测直接与固定化蛋白质靶点结合的小分子(“片段”)的方法公开(公告)号:US20080299673A1
公开(公告)日:2008-12-04
申请号:US12106283
申请日:2008-04-19
申请人: Rick Wagner , Lance Laing
发明人: Rick Wagner , Lance Laing
IPC分类号: G01N21/62
CPC分类号: G01N33/54373 , G01N21/7743 , G01N21/7746 , G01N2021/7773
摘要: The invention provides method of detecting interactions of small molecules with target molecules.
摘要翻译: 本发明提供了检测小分子与靶分子的相互作用的方法。
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公开(公告)号:US09778267B2
公开(公告)日:2017-10-03
申请号:US12171475
申请日:2008-07-11
申请人: Brant Binder , Lance Laing
发明人: Brant Binder , Lance Laing
IPC分类号: C12Q1/02 , G01N33/68 , G01N33/543
CPC分类号: G01N33/6872 , G01N33/54373
摘要: The invention provides methods for identifying modulators of ion channels without the use of recombinant cell lines over-expressing the ion channel proteins or the use of detection labels.
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公开(公告)号:US08298780B2
公开(公告)日:2012-10-30
申请号:US12335393
申请日:2008-12-15
IPC分类号: G01N33/551
CPC分类号: G01N21/63 , C40B30/04 , C40B30/10 , G01N21/4788 , G01N21/7743 , G01N33/54373
摘要: Methods are provided to detect changes in cells without the use of detection labels.
摘要翻译: 提供方法来检测细胞的变化,而不使用检测标记。
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9.HIGH-DENSITY POLYMER SURFACE COATING TO IMMOBILIZE CHEMICAL OR BIOLOGICAL MOLECULES 审中-公开
标题翻译: 高密度聚合物表面涂层化学或生物分子公开(公告)号:US20120101230A1
公开(公告)日:2012-04-26
申请号:US12366581
申请日:2009-02-05
申请人: Guobin (Frank) Wang , Lance Laing
发明人: Guobin (Frank) Wang , Lance Laing
IPC分类号: C08F8/00
CPC分类号: C08F8/34 , G01N33/54353 , G01N33/545 , C08F120/06
摘要: A method for providing high-density polymer surface for attaching proteins or peptides, and binding proteins, peptides, DNAs, cells, small molecules, and other chemical or biological molecules that are of interests in the areas of proteomic, genomic, pharmaceutical, drug discovery, and diagnostic studies.
摘要翻译: 提供高密度聚合物表面用于附着蛋白质或肽,以及结合蛋白质,肽,DNA,细胞,小分子以及其它在蛋白质组学,基因组学,药物学和药物发现领域有兴趣的化学或生物分子的方法 和诊断研究。
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公开(公告)号:US20090017488A1
公开(公告)日:2009-01-15
申请号:US12171475
申请日:2008-07-11
申请人: Brant Binder , Lance Laing
发明人: Brant Binder , Lance Laing
IPC分类号: C12Q1/02
CPC分类号: G01N33/6872 , G01N33/54373
摘要: The invention provides methods for identifying modulators of ion channels without the use of recombinant cell lines over-expressing the ion channel proteins or the use of detection labels.
摘要翻译: 本发明提供用于鉴定离子通道调节剂的方法,而不使用过表达离子通道蛋白的重组细胞系或检测标记的使用。
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