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公开(公告)号：US20180274131A1
公开(公告)日：2018-09-27
申请号：US15763197
申请日：2016-10-03
发明人： Christophe Pierre Edouard Naz , Anandkumar Nandakumar , Oleg Svanidze , Martijn Antonius Johannes Cox , Fabio Zomer Volpato
CPC分类号： D01D5/0084 , A61L27/18 , A61L27/34 , A61L31/10 , A61L2420/02 , D01D5/0046 , D01D5/0061 , D01D5/0069 , D01D5/0092 , D04H1/728 , D10B2509/06
摘要： Endoluminal and other as implantable prostheses are fabricated in electrospinning apparatus including a target and an applicator. A solution comprising a polymer and a solvent is directed to the target with a first electrical potential between the target and the applicator to produce a first set of fibers. The same or another solution is continued to be delivered through the applicator onto the target while applying a second electrical potential to produce a second set of fibers having a second solvent fraction, and the same or different solution may be delivered while applying a third potential difference to produce a laminated structure having at least three layers. By properly controlling the electrical potentials and solvent fractions, an adhesive layer can be formed to serve a glue or adhesive between the inner and outer layers, and a stent or other scaffold may be positioned between the inner and outer layers to form a covered stent or graft.
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公开(公告)号：US20200171210A1
公开(公告)日：2020-06-04
申请号：US16782253
申请日：2020-02-05
申请人： Xeltis, BV
摘要： The present disclosure provides methods, substrates and compositions for modifying, repairing, and/or engineering blood vessel tissue, and in particular the use of such compositions for treating a diseased blood vessel.
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公开(公告)号：US20190201588A1
公开(公告)日：2019-07-04
申请号：US16225045
申请日：2018-12-19
申请人： Xeltis, BV
CPC分类号： A61L27/58 , A61F2/2415 , A61L27/14 , A61L27/50 , A61L27/507 , A61L27/54 , A61L2430/20 , D01D5/0015
摘要： A biodegradable cardiovascular implant is provided for growing cardiovascular tissue in a patient. The implant distinguishes an electro-spun network with supramolecular compounds having hard-blocks covalently bonded with soft-blocks resulting in much enhanced durability and fatigue resistance, while maintaining the effectiveness as a cardiovascular implant.
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公开(公告)号：US20180325646A1
公开(公告)日：2018-11-15
申请号：US15940037
申请日：2018-06-12
申请人： Xeltis, BV
CPC分类号： A61F2/0077 , A61F2/06 , A61F2002/0081 , A61F2002/0091 , A61F2210/0004 , A61F2240/001 , A61F2250/0067 , A61L27/18 , A61L27/34 , A61L27/50 , A61L33/00 , A61L33/0005 , A61L33/0047 , A61L33/007 , A61L33/06 , A61M1/3655
摘要： A cardiovascular graft is provided with highly reduced thrombogenicity. The cardiovascular graft is an electrospun non-woven mesh produced from supramolecular polymers with large diameter fibers. The cardiovascular graft can be implemented as a vascular graft into the human body to allow vascular bypass/reconstruction, or repeated venous access for dialysis treatment, as well as other disorders of small-diameter blood vessels.
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公开(公告)号：US11510782B2
公开(公告)日：2022-11-29
申请号：US15770276
申请日：2016-10-27
申请人： Xeltis, BV
摘要： Bioabsorbable medical devices such as vascular closures, mitral chorea replacements, and mitral leaflet extensions are provided.
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公开(公告)号：US10687966B2
公开(公告)日：2020-06-23
申请号：US15842359
申请日：2017-12-14
申请人： Xeltis, BV
发明人： Tom Lavrijsen , Anandkumar Nandakumar , Martijn Antonius Johannes Cox , Franciscus Petrus Thomas Baaijens , Carolina Victoria Catharina Bouten , Anton Bosman , Tristan Mes , Patricia Yvonne Wilhelmina Dankers
IPC分类号： A61F2/86 , A61F2/91 , A61L27/18 , A61L27/50 , A61L27/56 , A61F2/00 , A61F2/24 , A61L27/54 , A61L27/58
摘要： The disclosure lies in the field of regenerative medicine and relates to an implant having a matrix material, and a method for manufacturing an implant having matrix material. The disclosure further relates to a crimped implant.
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公开(公告)号：US20180214611A1
公开(公告)日：2018-08-02
申请号：US15938220
申请日：2018-03-28
申请人： Xeltis, BV
IPC分类号： A61L27/50 , A61L27/34 , A61L27/26 , A61L27/58 , D01F6/62 , D04H1/4334 , D04H1/435 , D04H1/4374
CPC分类号： A61L27/507 , A61L27/18 , A61L27/26 , A61L27/34 , A61L27/54 , A61L27/58 , A61L2300/414 , A61L2300/426 , A61L2300/604 , A61L2300/606 , A61L2400/18 , D01F6/625 , D04H1/4334 , D04H1/435 , D04H1/4374 , C08L67/04
摘要： The present disclosure provides methods, substrates and compositions for modifying, repairing, and/or engineering blood vessel tissue, and in particular the use of such compositions for treating a diseased blood vessel.
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公开(公告)号：US20180235758A1
公开(公告)日：2018-08-23
申请号：US15770276
申请日：2016-10-27
申请人： Xeltis, BV
CPC分类号： A61F2/2463 , A61F2/2412 , A61F2/2454 , A61F2/246 , A61F2210/0004 , A61F2230/0013 , A61L27/507 , A61L27/58
摘要： Bioabsorbable medical devices such as vascular closures, mitral chorea replacements, and mitral leaflet extensions are provided.
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公开(公告)号：US20180153717A1
公开(公告)日：2018-06-07
申请号：US15842359
申请日：2017-12-14
申请人： Xeltis, BV
发明人： Tom Lavrijsen , Anandkumar Nandakumar , Martijn Antonius Johannes Cox , Franciscus Petrus Thomas Baaijens , Carolina Victoria Catharina Bouten , Anton Bosman , Tristan Mes , Patricia Yvonne Wilhelmina Dankers
IPC分类号： A61F2/86 , A61F2/00 , A61L27/58 , A61L27/56 , A61F2/24 , A61L27/54 , A61L27/50 , A61L27/18 , C08L67/04
摘要： The disclosure lies in the field of regenerative medicine and relates to an implant having a matrix material, and a method for manufacturing an implant having matrix material. The disclosure further relates to a crimped implant.
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