专利检索 ap:("Christopher DINSMORE" OR "Peter FULLER" OR "David GUERIN" OR "Christopher F. THOMPSON" OR "Qinglin PU" OR "Mark E. SCOTT" OR "Jason David KATZ" OR "Ravi KURUKLASURIYA" OR "Joshua T. CLOSE" OR "Danielle FALCONE" OR "Jason BRUDAKER" OR "Hongbo ZENG" OR "Yunfeng BAI" OR "Jianmin FU" OR "Norman KONG" OR "Yumei LIU" OR "Zhixiang ZHENG" OR "MERCK SHARP & DOHME CORP.") AND inv:"Jason David Katz" 第 1 页

1.

发明申请
N-(2-CYANO HETEROCYCLYL) PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS 有权
标题翻译： N-（2-氰基杂环基）吡唑并吡喃酮作为甘薯激酶抑制剂

公开(公告)号：US20160272633A1

公开(公告)日：2016-09-22

申请号：US14778052

申请日：2014-03-19

申请人： Christopher DINSMORE , Peter FULLER , David GUERIN , Christopher F. THOMPSON , Qinglin PU , Mark E. SCOTT , Jason David KATZ , Ravi KURUKLASURIYA , Joshua T. CLOSE , Danielle FALCONE , Jason BRUDAKER , Hongbo ZENG , Yunfeng BAI , Jianmin FU , Norman KONG , Yumei LIU , Zhixiang ZHENG , MERCK SHARP & DOHME CORP.

发明人： Christopher Dinsmore , Peter Fuller , David Guerin , Christopher F. Thompson , Qinglin Pu , Mark E. Scott , Jason David Katz , Ravi Kuruklasuriya , Joshua T. Close , Danielle Falcone , Jason Brubaker , Hongbo Zeng , Yunfeng Bai , Jianmin Fu , Norman Kong , Yumei Liu , Zhixiang Zheng

IPC分类号： C07D471/04 , C07D519/00

CPC分类号： C07D471/04 , C07D519/00

摘要： Provided are compounds of Formula I, a JAK inhibitor, and use thereof for the treatment of JAK-mediated diseases by the application.

2.

发明申请
CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS 有权
标题翻译：甘氨酸激酶抑制剂CYCLOALKYL NITRILE PYRAZOLO PYRIDONES

公开(公告)号：US20160280704A1

公开(公告)日：2016-09-29

申请号：US14778019

申请日：2014-03-19

申请人： Matthew Lloyd Childers , Christopher Dinsmore , Peter Fuller , David Guerin , Jason David Katz , Qinglin Pu , Mark E. Scott , Christopher F. Thompson , Hongjun Zhang , Danielle Falcone , Luis Torres , Jason Brubaker , Hongbo Zeng , Jiaqiang Cai , Xiaoxing Du , Chonggang Wang , Yunfeng Bai , Norman Kong , Yumei Liu , Zhixiang Zheng , Merck Sharp & Dohme Corp.

发明人： Matthew Lloyd Childers , Christopher Dinsmore , Peter Fuller , David Guerin , Jason David Katz , Qinglin Pu , Mark E. Scott , Christopher F. Thompson , Hongjun Zhang , Danielle Falcone , Luis Torres , Jason Brubaker , Hongbo Zeng , Jiaqiang Cai , Xiaoxing Du , Chonggang Wang , Yunfeng Bai , Norman Kong , Yumei Liu , Zhixiang Zheng

IPC分类号： C07D471/04 , C07D519/00

CPC分类号： C07D471/04 , C07D519/00

摘要： Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

3.

发明申请
ACYCLIC CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS 审中-公开
标题翻译：交联氰基乙基吡唑啉酮作为甘油激酶抑制剂

公开(公告)号：US20160272634A1

公开(公告)日：2016-09-22

申请号：US14778055

申请日：2014-03-19

申请人： Christopher DINSMORE , Peter FULLER , David GUERIN , Jason David KATZ , Christopher F. THOMPSON , Danielle FALCONE , Wei DENG , Luis TORRES , Hongbo ZENG , Yunfeng BAI , Jianmin FU , Norman KONG , Yumei LIU , Zhixiang ZHENG , Mark E. SCOTT , MERCK SHARP & DOHME CORP.

发明人： Christopher Dinsmore , Peter Fuller , David Guerin , Jason David Katz , Christopher F. Thompson , Danielle Falcone , Wei Deng , Luis Torres , Hongbo Zeng , Yunfeng Bai , Jianmin Fu , Norman Kong , Yumei Liu , Zhixiang Zheng , Mark E. Scott

IPC分类号： C07D471/04 , C07D519/00

CPC分类号： C07D471/04 , C07D519/00

摘要： The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

摘要翻译： 本发明提供了作为JAK抑制剂的式I化合物，因此可用于治疗JAK介导的疾病如类风湿性关节炎，哮喘，COPD和癌症。

4.

发明申请
GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS 有权
标题翻译：作为JANUS KINASE抑制剂的GEMYALLY取代的氰基乙基吡唑啉吡啶

公开(公告)号：US20160272632A1

公开(公告)日：2016-09-22

申请号：US14778046

申请日：2014-03-19

申请人： Matthew Lloyd CHILDERS , Peter FULLER , David GUERIN , Jason David KATZ , Qinglin PU , Mark E. SCOTT , Christopher E. THOMPSON , Michelle MARTINEZ , Danielle FALCONE , Luis TORRES , Yongqi DENG , Ravi KURUKULASURIYA , Hongbo ZENG , Yunfeng BAI , Norman KONG , Yumei LIU , MERCK SHARP & DOHME CORP.

发明人： Matthew Lloyd Childers , Peter Fuller , David Guerin , Jason David Katz , Qinglin Pu , Mark E. Scott , Christopher F. Thompson , Michelle Martinez , Danielle Falcone , Luis Torres , Yongqi Deng , Ravi Kurukulasuriya , Hongbo Zeng , Yunfeng Bai , Norman Kong , Yumei Liu , Zhixiang Zheng

IPC分类号： C07D471/04 , C07D519/00

CPC分类号： C07D471/04 , C07D519/00

摘要： The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

摘要翻译： 本发明提供了作为JAK抑制剂的式（I）化合物，因此可用于治疗JAK介导的疾病如类风湿性关节炎，哮喘，COPD和癌症。

5.

发明授权
Cyanomethylpyrazole carboxamides as janus kinase inhibitors 有权
标题翻译：氰基甲基吡唑甲酰胺作为甘蔗激酶抑制剂

公开(公告)号：US09328099B2

公开(公告)日：2016-05-03

申请号：US14345978

申请日：2012-09-21

申请人： Jason Brubaker , Matthew Lloyd Childers , Matthew Christopher , Joshua T. Close , Jason David Katz , Joon Jung , Scott Peterson , Phieng Siliphaivanh , Tony Siu , Graham Frank Smith , Luis E. Torres , Hyun Chong Woo , Jonathan R. Young , Hongjun Zhang

发明人： Jason Brubaker , Matthew Lloyd Childers , Matthew Christopher , Joshua T. Close , Jason David Katz , Joon Jung , Scott Peterson , Phieng Siliphaivanh , Tony Siu , Graham Frank Smith , Luis E. Torres , Hyun Chong Woo , Jonathan R. Young , Hongjun Zhang

IPC分类号： C07D231/38 , C07D405/04 , C07D401/14 , C07D401/04 , C07D403/04 , C07D405/08 , C07D403/12 , C07D401/12 , C07D403/08 , C07D405/12 , C07D409/12 , C07D413/12 , C07D401/06 , C07D403/06 , C07D405/06 , C07D405/14 , C07D409/04 , C07D413/14 , C07D417/14

CPC分类号： C07D405/08 , C07D231/38 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/08 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/14

摘要： The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

摘要翻译： 本发明提供了作为JAK抑制剂的式I化合物，因此可用于治疗JAK介导的疾病如类风湿性关节炎，哮喘，COPD和癌症。

6.

发明授权
N-(2-cyano heterocyclyl) pyrazolo pyridones as janus kinase inhibitors 有权

公开(公告)号：US09957265B2

公开(公告)日：2018-05-01

申请号：US14778052

申请日：2014-03-19

申请人： Merck Sharp & Dohme Corp.

发明人： Christopher Dinsmore , Peter Fuller , David Guerin , Christopher F. Thompson , Qinglin Pu , Mark E. Scott , Jason David Katz , Ravi Kurukulasuriya , Joshua T. Close , Danielle Falcone , Jason Brubaker , Hongbo Zeng , Yunfeng Bai , Jianmin Fu , Norman Kong , Yumei Liu , Zhixiang Zheng

IPC分类号： C07D471/04 , C07D519/00

CPC分类号： C07D471/04 , C07D519/00

摘要： Provided are compounds of Formula I, a JAK inhibitor, and use thereof for the treatment of JAK-mediated diseases by the application.

7.

发明授权
Acyclic cyanoethylpyrazolo pyridones as janus kinase inhibitors 有权

公开(公告)号：US10059705B2

公开(公告)日：2018-08-28

申请号：US14778055

申请日：2014-03-19

申请人： Merck Sharp & Dohme Corp.

发明人： Christopher Dinsmore , Peter Fuller , David Guerin , Jason David Katz , Christopher F. Thompson , Danielle Falcone , Wei Deng , Luis Torres , Hongbo Zeng , Yunfeng Bai , Jianmin Fu , Norman Kong , Yumei Liu , Zhixiang Zheng , Mark E. Scott

IPC分类号： C07D471/04 , C07D519/00

CPC分类号： C07D471/04 , C07D519/00

摘要： The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.