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公开(公告)号：US4897465A
公开(公告)日：1990-01-30
申请号：US256813
申请日：1988-10-12
CPC分类号： C07K1/34 , A23C9/1425
摘要： Disclosed are ultrafiltration processes for the enrichment and concentration of selected proteins from protein conaining fluids. Illustratively, IgG is concentrated from whey by means of multiple ultrafiltration "passes", using a metallic oxide ultrafiltration membrane, which are characterized by differing pH's.
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2.发明授权Debittered protein product having improved antigenicity and method for manufacture 失效具有改善的抗原性的抗转录蛋白产物和制造方法
公开(公告)号：US5837312A
公开(公告)日：1998-11-17
申请号：US717004
申请日：1996-09-20
摘要： A method for debittering and reducing the allergenic reactivity of protein hydrolysates is disclosed, which method includes the providing of an aqueous solution of a protein hydrolysate, feeding the solution into a bed of siloxane, and collecting a first portion of the solution exiting from the bed. The first portion contains either a non-bitter or bitter fraction. A second portion of the solution exiting from the bed can be collected which contains the opposite tasting fraction of the hydrolysate. Preferably the siloxane is selected from the group comprising octa-siloxane and octadecyl-siloxane. Preferably the hydrolysate has a molecular weight of less than 10,000, and is derived from the group of hydrolysates comprising casein, whey and soy. Additionally, the bed preferably is of a depth of between 2 to 4 times the bed diameter. A more hypoallergenic protein hydrolysate product produced in accordance with the method of the invention is also disclosed.
摘要翻译： 公开了一种用于降解和降低蛋白质水解产物的过敏反应性的方法，该方法包括提供蛋白质水解产物的水溶液，将溶液进料到硅氧烷床中，并收集从床层出来的溶液的第一部分 。 第一部分包含非苦味或苦味的部分。 可以收集从床中排出的溶液的第二部分，其含有相反的水解产物的品尝部分。 硅氧烷优选选自八硅氧烷和十八烷基硅氧烷。 优选地，水解产物具有小于10,000的分子量，并且衍生自包含酪蛋白，乳清和大豆的水解产物。 此外，床优选地是床直径的2至4倍之间的深度。 还公开了根据本发明的方法生产的更低的抗过敏蛋白质水解产物。
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公开(公告)号：US20120171350A1
公开(公告)日：2012-07-05
申请号：US13333949
申请日：2011-12-21
CPC分类号： A61K31/05 , A23K20/158 , A23K50/30 , A23L33/12 , A23L33/30 , A23L33/40 , A23V2002/00 , A61K9/00 , A61K31/20
摘要： Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component.
摘要翻译： 公开了营养配方，其包括可以对早产儿，婴儿，幼儿和儿童施用的预消化脂肪，用于改善营养物质的耐受性，消化和吸收以及降低坏死性小肠结肠炎，绞痛和短肠综合征的发生率。 预先消化的脂肪包括含脂肪酸的单甘油酯和/或脂肪酸组分。
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公开(公告)号：US5258178A
公开(公告)日：1993-11-02
申请号：US926181
申请日：1992-08-07
CPC分类号： C07K16/121 , A61K38/00
摘要： This invention describes a product obtained from the isolation and concentration of specific immunoglobulins (antibodies) derived from the mammary secretions of cows immunized with Helicobacter pylori. The product is useful in preparing formulations for the treatment and/or prevention of gastric diseases.
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公开(公告)号：US09078846B2
公开(公告)日：2015-07-14
申请号：US13333949
申请日：2011-12-21
CPC分类号： A61K31/05 , A23K20/158 , A23K50/30 , A23L33/12 , A23L33/30 , A23L33/40 , A23V2002/00 , A61K9/00 , A61K31/20
摘要： Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component.
摘要翻译： 公开了营养配方，其包括可以对早产儿，婴儿，幼儿和儿童施用的预消化脂肪，用于改善营养物质的耐受性，消化和吸收以及降低坏死性小肠结肠炎，绞痛和短肠综合征的发生率。 预先消化的脂肪包括含脂肪酸的单甘油酯和/或脂肪酸组分。
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公开(公告)号：US20130243904A1
公开(公告)日：2013-09-19
申请号：US13818486
申请日：2011-08-22
申请人： Christopher T. Cordle , Steven T. Luebbers , Larry W. Williams , Jeffrey Harris Baxter , Geralyn Duska-Mcewen
发明人： Christopher T. Cordle , Steven T. Luebbers , Larry W. Williams , Jeffrey Harris Baxter , Geralyn Duska-Mcewen
IPC分类号： A23L1/29
CPC分类号： A23L29/272 , A23L2/66 , A23L29/206 , A23L33/115 , A23L33/16 , A23L33/18 , A23L33/40 , A23V2002/00 , A61K36/48 , A61K38/011 , A23V2250/548
摘要： Disclosed are nutritional products comprising pea protein hydrolysates as a primary or sole source of protein. The nutritional products include nutritional liquids, powders, bars, and other food products, wherein the resulting nutritional products are physically stable over shelf life and provide favorable organoleptic properties. These nutritional products may be used as a nutritional source for individuals who are intolerant and/or allergic to cow milk proteins and soy proteins and/or who have malabsorption, maldigestion, or other gastroinstestinal conditions.
摘要翻译： 公开了包含豌豆蛋白水解物作为蛋白质的主要或唯一来源的营养产品。 营养产品包括营养液体，粉末，酒吧和其他食品，其中所得营养产品在保质期内物理稳定并提供有利的感官特性。 这些营养产品可以用作对牛奶蛋白质和大豆蛋白质不耐受和/或过敏的个体和/或吸收不良，消化不良或其它胃肠病症的个体的营养来源。
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7.发明授权Methods for improving tolerance, digestion, and lipid soluble nutrient absorption in an infant, toddler, or child 有权改善婴儿，幼儿或儿童耐受性，消化和脂溶性营养吸收的方法公开(公告)号：US08754126B2
公开(公告)日：2014-06-17
申请号：US13333943
申请日：2011-12-21
申请人： Chron-Si Lai , Keith A. Garleb , John B. Lasekan , Steven R. Davis , Christopher T. Cordle , Russell J. Merritt
发明人： Chron-Si Lai , Keith A. Garleb , John B. Lasekan , Steven R. Davis , Christopher T. Cordle , Russell J. Merritt
CPC分类号： A61K31/05 , A23K20/158 , A23K50/30 , A23L33/12 , A23L33/30 , A23L33/40 , A23V2002/00 , A61K9/00 , A61K31/20
摘要： Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component.
摘要翻译： 公开了营养配方，其包括可以对早产儿，婴儿，幼儿和儿童施用的预消化脂肪，用于改善营养物质的耐受性，消化和吸收以及降低坏死性小肠结肠炎，绞痛和短肠综合征的发生率。 预先消化的脂肪包括含脂肪酸的单甘油酯和/或脂肪酸组分。
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公开(公告)号：US06245803B1
公开(公告)日：2001-06-12
申请号：US09539029
申请日：1999-06-01
申请人： Phyllis J. B. Acosta , Marlene W. Borschel , Patricia A. Reynolds , Christopher T. Cordle , Geralyn O. Duska-McEwen
发明人： Phyllis J. B. Acosta , Marlene W. Borschel , Patricia A. Reynolds , Christopher T. Cordle , Geralyn O. Duska-McEwen
IPC分类号： A61K31385
CPC分类号： A23L33/175 , A23L33/10 , A23L33/115 , A23L33/15 , A23L33/16 , A23L33/40 , A23V2002/00 , Y10S426/801 , A23V2250/0608 , A23V2250/062 , A23V2250/188 , A23V2250/1944 , A23V2250/70 , A23V2250/156 , A23V2200/222 , A23V2250/06 , A23V2250/1874 , A23V2250/1872 , A23V2250/0644 , A23V2250/0612
摘要： This invention relates to a palatable elemental nutritional formula that is nutritionally complete for humans with specialized dietary needs. The nutritional of the present invention uses specific free amino acids to provide the source of amino nitrogen (protein equivalents) and a special blend of fats that provides 38 to 50% of the total Calories in a pleasant tasting formula. The nutritionally complete formula of this invention is useful for children having multiple protein allergies, short gut syndrome, sick gut, diarrhea and the like. More specifically, the nutritional product, in accordance with this invention, utilizes L-asparagine monohydrochloride and L-glutamine in place of L-aspartic acid and L-glutamic acid, respectively. In addition, the source of fat comprises soy, fractionated coconut oil (medium chain triglycerides), high oleic safflower oil and esterified glycerol emulsifiers. The level of fat Calories is about 38 to 50% of total Calories, which produces a product having a low osmolarity and provides required energy requirements in a small volume.
摘要翻译： 本发明涉及对具有特殊膳食需要的人营养完整的可口的元素营养配方。 本发明的营养物质使用特定的游离氨基酸提供氨基氮源（蛋白质当量）和脂肪的特殊混合物，其以愉快的品酒配方提供总卡路里的38至50％。 本发明的营养完全配方对于具有多种蛋白质过敏症，短肠综合征，病肠，腹泻等的儿童是有用的。 更具体地，根据本发明的营养产品分别使用L-天冬酰胺一盐酸盐和L-谷氨酰胺代替L-天冬氨酸和L-谷氨酸。 此外，脂肪源包括大豆，分馏椰子油（中链甘油三酯），高油酸红花油和酯化甘油乳化剂。 卡路里的脂肪含量约占卡路里总量的38％至50％，产生低摩尔渗透压浓度的产品，并在小体积内提供所需的能量需求。
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公开(公告)号：US5922766A
公开(公告)日：1999-07-13
申请号：US887001
申请日：1997-07-02
申请人： Phyllis J. B. Acosta , Marlene W. Borschel , Patricia A. Reynolds , Christopher T. Cordle , Geralyn O. Duska-McEwen
发明人： Phyllis J. B. Acosta , Marlene W. Borschel , Patricia A. Reynolds , Christopher T. Cordle , Geralyn O. Duska-McEwen
IPC分类号： A23L1/29 , A23L1/30 , A23L1/302 , A23L1/304 , A23L1/305 , A61K9/08 , A61K9/14 , A61K31/18 , A61K31/23 , A61K31/70 , A61K36/00 , A61K36/28 , A61K36/899 , A61P3/02 , A61K31/415
CPC分类号： A23L33/175 , A23L33/10 , A23L33/115 , A23L33/15 , A23L33/16 , A23L33/40 , A23V2002/00 , Y10S426/801
摘要： This invention relates to a palatable elemental nutritional formula that is nutritionally complete for humans with specialized dietary needs. The nutritional of the present invention uses specific free amino acids to provide the source of amino nitrogen (protein equivalents) and a special blend of fats that provides 38 to 50% of the total Calories in a pleasant tasting formula. The nutritionally complete formula of this invention is useful for children having multiple protein allergies, short gut syndrome, sick gut, diarrhea and the like. More specifically, the nutritional product, in accordance with this invention, utilizes L-asparagine monohydrochloride and L-glutamine in place of L-aspartic acid and L-glutamic acid, respectively. In addition, the source of fat comprises soy, fractionated coconut oil (medium chain triglycerides), high oleic safflower oil and esterified glycerol emulsifiers. The level of fat Calories is about 38 to 50% of total Calories, which produces a product having a low osmolarity and provides required energy requirements in a small volume.
摘要翻译： 本发明涉及对具有特殊膳食需要的人营养完整的可口的元素营养配方。 本发明的营养物质使用特定的游离氨基酸提供氨基氮源（蛋白质当量）和脂肪的特殊混合物，其以愉快的品酒配方提供总卡路里的38至50％。 本发明的营养完全配方对于具有多种蛋白质过敏症，短肠综合征，病肠，腹泻等的儿童是有用的。 更具体地，根据本发明的营养产品分别使用L-天冬酰胺一盐酸盐和L-谷氨酰胺代替L-天冬氨酸和L-谷氨酸。 此外，脂肪源包括大豆，分馏椰子油（中链甘油三酯），高油酸红花油和酯化甘油乳化剂。 卡路里的脂肪含量约占卡路里总量的38％至50％，产生低摩尔渗透压浓度的产品，并在小体积内提供所需的能量需求。
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10.发明申请公开(公告)号：US20120172445A1
公开(公告)日：2012-07-05
申请号：US13333953
申请日：2011-12-21
CPC分类号： A61K31/05 , A23K20/158 , A23K50/30 , A23L33/12 , A23L33/30 , A23L33/40 , A23V2002/00 , A61K9/00 , A61K31/20
摘要： Disclosed are nutritional formulations including predigested fats that can be administered to preterm infants, infants, toddlers, and children for improving tolerance, digestion, and absorption of nutrients and for reducing the incidence of necrotizing enterocolitis, colic, and short bowel syndrome. The predigested fats include fatty acid-containing monoglycerides and/or a fatty acid component.
摘要翻译： 公开了营养配方，其包括可以对早产儿，婴儿，幼儿和儿童施用的预消化脂肪，用于改善营养物质的耐受性，消化和吸收以及降低坏死性小肠结肠炎，绞痛和短肠综合征的发生率。 预先消化的脂肪包括含脂肪酸的单甘油酯和/或脂肪酸组分。
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