公开(公告)号：US20140091255A1

公开(公告)日：2014-04-03

申请号：US14115298

申请日：2012-04-18

申请人： Chun Joong Kim ,  Seon Ju Choi ,  Soo Chan Kim ,  Dong Gyu Chang ,  Keon Il Kim ,  Woo Young Yang

发明人： Chun Joong Kim ,  Seon Ju Choi ,  Soo Chan Kim ,  Dong Gyu Chang ,  Keon Il Kim ,  Woo Young Yang

IPC分类号： H01M4/485 ,  C01D15/02

CPC分类号： C01D15/02 ,  C01G23/005 ,  C01P2002/72 ,  C01P2002/85 ,  H01M4/485

摘要： A method of preparing an electrode active material for manufacturing a lithium secondary battery exhibiting stable charging/discharging efficiency and life-cycle characteristics even during high-speed charging/discharging cycles is provided. Also, a method of controlling both a composition ratio (Ti/Li) of surface elements and a composition of a lithium element in a lithium titanium oxide which is known to be an electrode active material having a relatively stable structure is provided. The lithium secondary battery using the lithium titanium oxide manufactured by the method as the electrode active material can be stably used by maintaining charging/discharging efficiency and charging capacity even during the high-speed charging/discharging cycles.

摘要翻译： 提供了即使在高速充电/放电循环期间制备显示出稳定的充放电效率和寿命特性的锂二次电池的电极活性材料的方法。 此外，提供了一种控制表面元素的组成比（Ti / Li）和已知为具有相对稳定的结构的电极活性材料的锂二氧化钛中的锂元素的组成的方法。 即使在高速充放电循环期间，也可以通过保持充放电效率和充电能力，稳定地使用利用该方法制造的锂二氧化钛作为电极活性物质的锂二次电池。

公开(公告)号：US20130202565A1

公开(公告)日：2013-08-08

申请号：US13702975

申请日：2011-06-08

申请人： Jung-Keug Park ,  Sung Min Kim ,  Soo Chan Kim ,  Moon Young Yoon ,  Hyun Jin Cho ,  Young-Kwon Seo ,  Hee Hoon Yoon

发明人： Jung-Keug Park ,  Sung Min Kim ,  Soo Chan Kim ,  Moon Young Yoon ,  Hyun Jin Cho ,  Young-Kwon Seo ,  Hee Hoon Yoon

IPC分类号： C12N13/00

CPC分类号： C12N5/0619 ,  C12N5/0618 ,  C12N13/00 ,  C12N2506/1346 ,  C12N2506/1353 ,  C12N2506/1361 ,  C12N2506/1369 ,  C12N2506/1384 ,  C12N2529/00

摘要： The present invention relates to a method for differentiation of mesenchymal stem cells or dental pulp stem cells. More specifically, the invention relates to a method for differentiating stem cells to neural cells by applying mesenchymal stem cells or dental pulp stem cells with a low-frequency electromagnetic field. The differentiation method according to the present invention can induce differentiation even with low-cost mediums rather than induced neural differentiation mediums which are expensive due to addition of growth factors, and the neural cells differentiated according to the present invention may be useful for treatment of neurological brain diseases.

摘要翻译： 本发明涉及分化间充质干细胞或牙髓干细胞的方法。 更具体地，本发明涉及通过用低频电磁场施用间充质干细胞或牙髓干细胞来分化干细胞与神经细胞的方法。 根据本发明的分化方法即使使用低成本培养基也可诱导分化，而不是由于生长因子的添加而昂贵的诱导神经分化培养基，并且根据本发明分化的神经细胞可用于治疗神经系统 脑疾病

公开(公告)号：US08673605B2

公开(公告)日：2014-03-18

申请号：US13702975

申请日：2011-06-08

申请人： Jung-Keug Park ,  Sung Min Kim ,  Soo Chan Kim ,  Moon Young Yoon ,  Hyun Jin Cho ,  Young-Kwon Seo ,  Hee Hoon Yoon

发明人： Jung-Keug Park ,  Sung Min Kim ,  Soo Chan Kim ,  Moon Young Yoon ,  Hyun Jin Cho ,  Young-Kwon Seo ,  Hee Hoon Yoon

IPC分类号： A01N63/00 ,  C12N13/00 ,  C12N5/0793

CPC分类号： C12N5/0619 ,  C12N5/0618 ,  C12N13/00 ,  C12N2506/1346 ,  C12N2506/1353 ,  C12N2506/1361 ,  C12N2506/1369 ,  C12N2506/1384 ,  C12N2529/00

摘要： The present invention relates to a method for differentiation of mesenchymal stem cells or dental pulp stem cells. More specifically, the invention relates to a method for differentiating stem cells to neural cells by applying mesenchymal stem cells or dental pulp stem cells with a low-frequency electromagnetic field. The differentiation method according to the present invention can induce differentiation even with low-cost mediums rather than induced neural differentiation mediums which are expensive due to addition of growth factors, and the neural cells differentiated according to the present invention may be useful for treatment of neurological brain diseases.

摘要翻译： 本发明涉及分化间充质干细胞或牙髓干细胞的方法。 更具体地，本发明涉及通过用低频电磁场施用间充质干细胞或牙髓干细胞来分化干细胞与神经细胞的方法。 根据本发明的分化方法即使使用低成本培养基也可诱导分化，而不是由于生长因子的添加而昂贵的诱导神经分化培养基，并且根据本发明分化的神经细胞可用于治疗神经系统 脑疾病

公开(公告)号：US07359750B2

公开(公告)日：2008-04-15

申请号：US10668834

申请日：2003-09-23

申请人： Chul Gyu Song ,  Jeong Hwan Seo ,  Deok Won Kim ,  Soo Chan Kim ,  Dae Young Youn ,  Jong Chan Kim ,  Hee Chang Lee

发明人： Chul Gyu Song ,  Jeong Hwan Seo ,  Deok Won Kim ,  Soo Chan Kim ,  Dae Young Youn ,  Jong Chan Kim ,  Hee Chang Lee

IPC分类号： A61B5/05

CPC分类号： A61B5/4528 ,  A61B5/053 ,  A61B5/1071 ,  A61B5/1121 ,  A61B5/1126 ,  A61B5/4519 ,  A61B5/744

摘要： Disclosed herein is an apparatus and method for measuring bio-impedance attributable to joint movement. The bio-impedance measuring apparatus includes a constant current source, current stimulus electrodes, at least two voltage detection electrodes, a demodulator, a signal gain and offset controller and an isolated amplifier. The method of measuring bio-impedance attributable to joint movement, comprising the steps: generating a weak current by use of a constant current source; causing the weak current to flow from a point to another point; forming L voltage detecting electrode pairs from voltage detecting electodes positioned at m points on each of n-1 lines that divide an interval between a first joint and a second joint, between which the weak current flows, into equal n parts (m and n are natural numbers), using combination (mC2=L); detecting bio-impedance at certain periods from J (L-K) voltage detecting electrode pairs that are obtained by subtracting K voltage detecting electrode pairs, each of which exists on a single dividing line, from the formed L voltage detecting electrode pairs; and selecting a pair of voltage detecting electrodes having a highest variation of bio-impedance.

摘要翻译： 本文公开了一种用于测量归因于关节运动的生物阻抗的装置和方法。 生物阻抗测量装置包括恒流源，电流刺激电极，至少两个电压检测电极，解调器，信号增益和偏移控制器以及隔离放大器。 测量由联合运动引起的生物阻抗的方法，包括以下步骤：利用恒流源产生弱电流; 导致弱电流从一点流向另一点; 形成L电压检测电极对，该电压检测电极定位在n-1线上的每个m行上的m个点处，该第一接头和第二接头之间的间隔在弱电流流动之间分成相等的n个部分（m和n是 自然数），使用组合（mC2 = L）; 通过从形成的L电压检测电极对中减去存在于单个分割线上的K个电压检测电极对而获得的J（L-K）个电压检测电极对的特定周期的生物阻抗检测; 以及选择生物阻抗变化最大的一对电压检测电极。