公开(公告)号：US20070118027A1

公开(公告)日：2007-05-24

申请号：US11283506

申请日：2005-11-18

申请人： Clark Baker ,  Joseph Schmitt ,  Shannon Campbell ,  Nick Durr ,  Carine Hoarau ,  Rafael Ostrowski ,  Martin Debreczeny

发明人： Clark Baker ,  Joseph Schmitt ,  Shannon Campbell ,  Nick Durr ,  Carine Hoarau ,  Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： A61B5/00

CPC分类号： G01N21/359 ,  A61B5/0059 ,  A61B5/0537 ,  A61B5/4869 ,  G01N21/274

摘要： The present disclosure provides systems, devices, and/or methods for assessing body fluid-related metrics and/or changes therein. The disclosure further provides systems, devices, and/or methods for correlating body fluid-related metrics in a particular tissue with the corresponding whole-body metric. The disclosure also provides, systems, devices, and/or methods for assessment of such metrics to facilitate diagnosis and/or therapeutic interventions related to maintaining and/or restoring body fluid balance.

摘要翻译： 本公开提供了用于评估体液相关度量和/或其中变化的系统，装置和/或方法。 本公开还提供用于将特定组织中的体液相关度量与相应的全身度量相关联的系统，装置和/或方法。 本公开还提供了用于评估这些度量的系统，装置和/或方法，以促进与维持和/或恢复体液平衡相关的诊断和/或治疗干预。

公开(公告)号：US08175665B2

公开(公告)日：2012-05-08

申请号：US11716482

申请日：2007-03-09

申请人： Clark R. Baker, Jr. ,  Nicholas J. Durr ,  Murtaza Mogri ,  Carine Hoarau ,  Rafael Ostrowski ,  Martin P. Debreczeny

发明人： Clark R. Baker, Jr. ,  Nicholas J. Durr ,  Murtaza Mogri ,  Carine Hoarau ,  Rafael Ostrowski ,  Martin P. Debreczeny

IPC分类号： A61B5/1455

CPC分类号： A61B5/0059 ,  A61B5/4869 ,  A61B5/4878

摘要： Methods and systems for calculating body fluid metrics are provided. In accordance with an exemplary embodiment of the present technique, there is provided a method for calculating body fluid metrics by acquiring an absorbance spectrum of a subject's tissue over a range of near-infrared light, performing a multi-linear regression of the absorbance spectrum of the subject's tissue in relation to absorbance spectra of tissue constituents, and calculating body fluid metrics based on the results of the multi-linear regression. A system is provided having a sensor for emitting the light into the subject's tissue and detecting reflected, scattered, or transmitted light, a spectrometer for processing the detected light and generating the absorbance spectrum of the subject's tissue, memory for storing absorbance spectra of the tissue constituents and a multi-linear regression model, and a processor for performing the multi-linear regression and calculating the body fluid metrics.

摘要翻译： 提供了用于计算体液量度的方法和系统。 根据本技术的示例性实施例，提供了一种通过在近红外光范围内获取受试者组织的吸收光谱来计算体液量度的方法，执行吸收光谱的多线性回归 相关于组织成分的吸收光谱的受试者组织，以及基于多线性回归的结果计算体液量度。 提供一种具有用于将光发射到被检体的组织中并检测反射，散射或透射光的传感器的系统，用于处理检测到的光并产生受试者组织的吸收光谱的光谱仪，用于存储组织的吸收光谱的存储器 成分和多线性回归模型，以及用于执行多线性回归和计算体液量度的处理器。

公开(公告)号：US20080221412A1

公开(公告)日：2008-09-11

申请号：US11716482

申请日：2007-03-09

申请人： Clark R. Baker, ,  Nicholas J. Durr ,  Murtaza Mogri ,  Carine Hoarau ,  Rafael Ostrowski ,  Martin P. Debreczeny

发明人： Clark R. Baker, ,  Nicholas J. Durr ,  Murtaza Mogri ,  Carine Hoarau ,  Rafael Ostrowski ,  Martin P. Debreczeny

IPC分类号： A61B5/00

CPC分类号： A61B5/0059 ,  A61B5/4869 ,  A61B5/4878

摘要： Methods and systems for calculating body fluid metrics are provided. In accordance with an exemplary embodiment of the present technique, there is provided a method for calculating body fluid metrics by acquiring an absorbance spectrum of a subject's tissue over a range of near-infrared light, performing a multi-linear regression of the absorbance spectrum of the subject's tissue in relation to absorbance spectra of tissue constituents, and calculating body fluid metrics based on the results of the multi-linear regression. A system is provided having a sensor for emitting the light into the subject's tissue and detecting reflected, scattered, or transmitted light, a spectrometer for processing the detected light and generating the absorbance spectrum of the subject's tissue, memory for storing absorbance spectra of the tissue constituents and a multi-linear regression model, and a processor for performing the multi-linear regression and calculating the body fluid metrics.

摘要翻译： 提供了用于计算体液量度的方法和系统。 根据本技术的示例性实施例，提供了一种通过在近红外光范围内获取受试者组织的吸收光谱来计算体液量度的方法，执行吸收光谱的多线性回归 相关于组织成分的吸收光谱的受试者组织，以及基于多线性回归的结果计算体液量度。 提供一种具有用于将光发射到被检体的组织中并检测反射，散射或透射光的传感器的系统，用于处理检测到的光并产生受试者组织的吸收光谱的光谱仪，用于存储组织的吸收光谱的存储器 成分和多线性回归模型，以及用于执行多线性回归和计算体液量度的处理器。

公开(公告)号：US08449834B2

公开(公告)日：2013-05-28

申请号：US11526417

申请日：2006-09-25

申请人： Rafael Ostrowski ,  Martin Debreczeny

发明人： Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： G01N21/75

CPC分类号： G01N31/223

摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.

公开(公告)号：US20080083265A1

公开(公告)日：2008-04-10

申请号：US11526369

申请日：2006-09-25

申请人： Rafael Ostrowski ,  Martin Debreczeny

发明人： Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： G01N33/497

CPC分类号： G01N33/004 ,  Y02A50/244

摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.

公开(公告)号：US20080081003A1

公开(公告)日：2008-04-03

申请号：US11526417

申请日：2006-09-25

申请人： Rafael Ostrowski ,  Martin Debreczeny

发明人： Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： G01N31/22 ,  G01N33/52

CPC分类号： G01N31/223

摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.

摘要翻译： 本发明涉及具有硼硅酸盐基质的二氧化碳检测器。 也可以在硼硅酸盐基材上设置二氧化碳响应指示剂溶液。 二氧化碳检测器可以是二氧化碳检测器系统的一部分，其还包括可操作地连接到壳体的空气进气口，以允许空气到达二氧化碳检测器。 二氧化碳检测器可以包括硼硅酸盐底物和设置在硼硅酸盐衬底上的二氧化碳响应指示剂溶液。 该检测器可以是另一系统的一部分，例如复苏系统。 检测器可以通过用二氧化碳响应指示剂溶液润湿硼硅酸盐底物并干燥指示剂溶液以使其固化并形成干燥的二氧化碳检测器来制备。 它可以用于通过将检测器暴露于样品来检测空气样品中二氧化碳的浓度。

公开(公告)号：US20080078394A1

公开(公告)日：2008-04-03

申请号：US11526393

申请日：2006-09-25

申请人： Rafael Ostrowski ,  Martin Debreczeny

发明人： Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： A61M16/00 ,  G01N31/22 ,  G01N33/52 ,  B01J20/10

CPC分类号： G01N31/223 ,  A61B5/0836 ,  A61M2016/103 ,  A61M2230/432 ,  B01J20/10 ,  B01J20/2803 ,  B01J20/28033 ,  B01J2220/49

摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.

公开(公告)号：US08431087B2

公开(公告)日：2013-04-30

申请号：US11526393

申请日：2006-09-25

申请人： Rafael Ostrowski ,  Martin Debreczeny

发明人： Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： G01N21/75

CPC分类号： G01N31/223 ,  A61B5/0836 ,  A61M2016/103 ,  A61M2230/432 ,  B01J20/10 ,  B01J20/2803 ,  B01J20/28033 ,  B01J2220/49

摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.

公开(公告)号：US08420405B2

公开(公告)日：2013-04-16

申请号：US11526369

申请日：2006-09-25

申请人： Rafael Ostrowski ,  Martin Debreczeny

发明人： Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： G01N21/77

CPC分类号： G01N33/004 ,  Y02A50/244

摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.

摘要翻译： 本发明涉及具有硼硅酸盐基质的二氧化碳检测器。 也可以在硼硅酸盐基材上设置二氧化碳响应指示剂溶液。 二氧化碳检测器可以是二氧化碳检测器系统的一部分，其还包括可操作地连接到壳体的空气进气口，以允许空气到达二氧化碳检测器。 二氧化碳检测器可以包括硼硅酸盐底物和设置在硼硅酸盐衬底上的二氧化碳响应指示剂溶液。 该检测器可以是另一系统的一部分，例如复苏系统。 检测器可以通过用二氧化碳响应指示剂溶液润湿硼硅酸盐底物并干燥指示剂溶液以使其固化并形成干燥的二氧化碳检测器来制备。 它可以用于通过将检测器暴露于样品来检测空气样品中二氧化碳的浓度。

公开(公告)号：US20080075633A1

公开(公告)日：2008-03-27

申请号：US11526834

申请日：2006-09-25

申请人： Rafael Ostrowski ,  Martin Debreczeny

发明人： Rafael Ostrowski ,  Martin Debreczeny

IPC分类号： A61B5/00 ,  G01N31/22

CPC分类号： G01N31/223 ,  A61M16/0084 ,  A61M16/08 ,  A61M16/0816 ,  A61M16/0825 ,  A61M2016/0413 ,  G01N21/78

摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.