公开(公告)号：US10959932B2

公开(公告)日：2021-03-30

申请号：US16067014

申请日：2016-12-30

Applicant: Colgate-Palmolive Company

Inventor： Carlo Daep ,  Michael Fitzgerald ,  Ekta Makwana ,  Peter R. Hilliard, Jr. ,  Shamim Ansari ,  Robert D'Ambrogio

IPC: A61K8/64 ,  C01B33/149 ,  A61Q11/00 ,  A61K8/02 ,  A61K9/00 ,  A61K8/44 ,  A61K8/25 ,  A61K6/54 ,  A61K47/60 ,  A61K8/21 ,  A61K8/27 ,  A61K38/17 ,  A61K9/16

Abstract: Disclosed herein is mucin-coated silica, compositions comprising the same, and methods of promoting the aggregation and/or clearance of oral bacteria using such compositions.

公开(公告)号：US11667947B2

公开(公告)日：2023-06-06

申请号：US16704052

申请日：2019-12-05

Applicant: Colgate-Palmolive Company

Inventor： Ekta Makwana ,  Carlo Daep

IPC: C12Q1/18 ,  G16B40/10 ,  C12Q1/02 ,  C12Q1/24 ,  G06F17/15

CPC classification number: C12Q1/18 ,  C12Q1/025 ,  C12Q1/24 ,  G06F17/15 ,  G16B40/10

Abstract: Described herein are methods and systems for identifying a composition having anti-pathogenic activity; evaluating the anti-pathogenic activity of a composition; measuring the metabolic function of a pathogen; and/or comparing the anti-pathogenic performance of a plurality of compositions.

公开(公告)号：US10912731B2

公开(公告)日：2021-02-09

申请号：US15668913

申请日：2017-08-04

Applicant: Colgate-Palmolive Company

Inventor： Carl Myers ,  Rehana Begum-Gafur ,  Jeffrey Merl Miller ,  Ekta Makwana

IPC: A61K8/86 ,  A61Q11/00 ,  A61K8/84 ,  A61K8/24 ,  A61K8/44 ,  A61K8/03 ,  A61Q17/00

Abstract: This application provides, among other things, novel aqueous biphasic oral care compositions comprising two distinct aqueous phases, useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.

公开(公告)号：US11497694B2

公开(公告)日：2022-11-15

申请号：US16215028

申请日：2018-12-10

Applicant: Colgate-Palmolive Company

Inventor： Carl Myers ,  Guillaume Picquet ,  Ekta Makwana

IPC: A61K8/24 ,  A61K8/86 ,  A61Q11/00 ,  A61K8/49 ,  A61K8/81 ,  A61K8/44 ,  A61K8/90 ,  A61K8/41

Abstract: This application provides, among other things, novel aqueous monophasic compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.

公开(公告)号：US20190038545A1

公开(公告)日：2019-02-07

申请号：US15668913

申请日：2017-08-04

Applicant: Colgate-Palmolive Company

Inventor： Carl Myers ,  Rehana Begum-Gafur ,  Jeffrey Merl Miller ,  Ekta Makwana

IPC: A61K8/86 ,  A61Q11/00 ,  A61K8/84 ,  A61K8/24 ,  A61K8/44

Abstract: This application provides, among other things, novel aqueous biphasic oral care compositions comprising two distinct aqueous phases, useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.