公开(公告)号：US20190271037A1

公开(公告)日：2019-09-05

申请号：US16297379

申请日：2019-03-08

Applicant: Complete Genomics, Inc.

Inventor： Rongqin Ke ,  Snezana Drmanac ,  Radoje Drmanac ,  Guangyang Cai ,  Matthew Callow

IPC: C12Q1/6874 ,  C12Q1/6806

Abstract: This application discloses methods of producing a DNA strand for sequencing, as well as genetic constructs, libraries, and arrays using DNA strands produced according to these methods. The application also discloses methods of sequencing using the DNA strands, genetic constructs, libraries, and arrays produced. In certain aspects, DNA being sequenced includes a target sequence and at least one adaptor sequence.

公开(公告)号：US20130296173A1

公开(公告)日：2013-11-07

申请号：US13868000

申请日：2013-04-22

Applicant: Complete Genomics, Inc.

Inventor： Matthew Callow ,  Linsu Chen ,  Dennis Ballinger

IPC: C12Q1/68

CPC classification number: C12Q1/6874 ,  C12Q2527/125

Abstract: The present invention is directed to compositions and methods for improving the discordance rate and mapping yield in nucleic acid sequencing reactions.

Abstract translation: 本发明涉及用于提高核酸测序反应中不一致率和测绘产率的组合物和方法。

公开(公告)号：US10227647B2

公开(公告)日：2019-03-12

申请号：US15040906

申请日：2016-02-10

Applicant: Complete Genomics, Inc.

Inventor： Rongqin Ke ,  Snezana Drmanac ,  Radoje Drmanac ,  Guangyang Cai ,  Matthew Callow

IPC: C12Q1/68 ,  C12Q1/6874 ,  C12Q1/6806

Abstract: This application discloses methods of producing a DNA strand for sequencing, as well as genetic constructs, libraries, and arrays using DNA strands produced according to these methods. The application also discloses methods of sequencing using the DNA strands, genetic constructs, libraries, and arrays produced. In certain aspects, DNA being sequenced includes a target sequence and at least one adaptor sequence.

公开(公告)号：US20170152554A1

公开(公告)日：2017-06-01

申请号：US15425791

申请日：2017-02-06

Applicant: Complete Genomics, Inc

Inventor： RADOJE DRMANAC ,  Matthew Callow ,  Snezana Drmanac ,  Brian K. Hauser ,  George Yeung

IPC: C12Q1/68

CPC classification number: C12Q1/6874 ,  C07H21/04 ,  C07K1/047 ,  C12Q1/6806 ,  C12Q1/682 ,  C12Q1/6837 ,  C12Q1/6869 ,  C12Q2525/151 ,  C12Q2525/313 ,  C12Q2531/125 ,  C12Q2565/513 ,  G01N15/1404 ,  G01N15/1434 ,  Y10S977/778 ,  Y10S977/789 ,  Y10S977/792 ,  Y10S977/88 ,  Y10S977/882 ,  C12Q2521/307 ,  C12Q2525/161 ,  C12Q2535/122 ,  C12Q2563/179 ,  C12Q2565/514

Abstract: A high density DNA array comprising a patterned surface, said surface comprising a pattern of small DNA binding regions separated by a non-DNA binding surface, wherein the DNA binding regions comprise DNA capture chemistry and the non-DNA binding surface does not have the DNA capture chemistry wherein more than 50% of the DNA binding regions in the array have single informative DNA species.

公开(公告)号：US20160237488A1

公开(公告)日：2016-08-18

申请号：US15040906

申请日：2016-02-10

Applicant: Complete Genomics, Inc.

Inventor： Rongqin Ke ,  Snezana Drmanac ,  Radoje Drmanac ,  Guangyang Cai ,  Matthew Callow

IPC: C12Q1/68

CPC classification number: C12Q1/6874 ,  C12Q1/6806 ,  C12Q2525/191 ,  C12Q2531/119

Abstract: This application discloses methods of producing a DNA strand for sequencing, as well as genetic constructs, libraries, and arrays using DNA strands produced according to these methods. The application also discloses methods of sequencing using the DNA strands, genetic constructs, libraries, and arrays produced. In certain aspects, DNA being sequenced includes a target sequence and at least one adaptor sequence.

Abstract translation: 本申请公开了用于测序的DNA链的制备方法，以及使用根据这些方法制备的DNA链的遗传构建体，文库和阵列。 本申请还公开了使用DNA链，遗传构建体，文库和产生的阵列进行测序的方法。 在某些方面，被测序的DNA包括靶序列和至少一个衔接子序列。

公开(公告)号：US11319588B2

公开(公告)日：2022-05-03

申请号：US16297379

申请日：2019-03-08

Applicant: Complete Genomics, Inc.

Inventor： Rongqin Ke ,  Snezana Drmanac ,  Radoje Drmanac ,  Guangyang Cai ,  Matthew Callow

IPC: C12Q1/6806 ,  C12Q1/6874

Abstract: This application discloses methods of producing a DNA strand for sequencing, as well as genetic constructs, libraries, and arrays using DNA strands produced according to these methods. The application also discloses methods of sequencing using the DNA strands, genetic constructs, libraries, and arrays produced. In certain aspects, DNA being sequenced includes a target sequence and at least one adaptor sequence.