公开(公告)号：US20210277405A1

公开(公告)日：2021-09-09

申请号：US17205008

申请日：2021-03-18

申请人： Conagen Inc. ,  Sumitomo Chemical Co., Ltd.

发明人： Ilya Tikh ,  Sonya Clarkson ,  Brendon Dusel ,  Jacob Edward Vick ,  Xiaodan Yu ,  Bryan Salas-Santiago

IPC分类号： C12N15/77 ,  C12P1/04

摘要： The present invention relates to the creation of a control system within a host cell to limit or eliminate degradation of key specified products at certain times during fermentation and to redirect the metabolic flux of the cell toward higher production of same key specified products.

公开(公告)号：US20240043894A1

公开(公告)日：2024-02-08

申请号：US18052595

申请日：2022-11-04

申请人： Conagen Inc.

发明人： David Nunn ,  Jacob Edward Vick ,  Bryan Salas-Santiago

IPC分类号： C12P19/36 ,  C12P19/30 ,  C12N9/12 ,  C12N9/10 ,  C12N9/24 ,  C12N9/02 ,  C12N9/14 ,  C12N9/78

CPC分类号： C12P19/36 ,  C12P19/30 ,  C12N9/1235 ,  C12Y207/06001 ,  C12N9/1077 ,  C12Y204/02012 ,  C12N9/1241 ,  C12Y207/07018 ,  C12N9/2497 ,  C12Y302/02001 ,  C12N9/0036 ,  C12Y106/01001 ,  C12N9/14 ,  C12Y306/01022 ,  C12N9/78 ,  C12Y305/01019

摘要： The present invention relates to microbial production of nicotinamide mononucleotide (NMN), nicotinamide riboside (NR), and nicotinamide adenine dinucleotide (NAD) using a genetically modified bacterium.