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    TYPE OF UNIVERSAL PROBE FOR THE DETECTION OF GENOMIC VARIANTS
    5.
    发明申请
    TYPE OF UNIVERSAL PROBE FOR THE DETECTION OF GENOMIC VARIANTS 审中-公开
    通用探头类型，用于检测基因组变体

    公开(公告)号：US20120225428A1

    公开(公告)日：2012-09-06

    申请号：US13411902

    申请日：2012-03-05

    申请人： Reinhard Beck ,  Frank Bergmann ,  Rita Haerteis ,  Dieter Heindl ,  Ralf Mauritz ,  Heiko Walch

    发明人： Reinhard Beck ,  Frank Bergmann ,  Rita Haerteis ,  Dieter Heindl ,  Ralf Mauritz ,  Heiko Walch

    IPC分类号： C12Q1/68 ,  G01N21/64

    CPC分类号： C12Q1/6832 ,  C12Q1/6827 ,  C12Q2525/101 ,  C12Q2525/204

    摘要： The present disclosure relates to a composition comprising a first set of probes and a second set of probes, composed of one or more DNA nucleotide(s) and five or more LNA (locked nucleic acid) nucleotides, wherein the base at a discriminating position differs for a first probe of the first set and a first probe of the second set. The present disclosure relates to the composition comprising a plurality of probes in each of the first and second set of probes, wherein the probes in each set differ in one, two, or three LNA random position(s). Further, the present disclosure relates to a method of detecting genomic variants by means of the aforementioned probes.

    摘要翻译： 本公开涉及包含由一个或多个DNA核苷酸和五个或更多个LNA（锁定的核酸）核苷酸组成的第一组探针和第二组探针的组合物，其中鉴别位置处的碱基不同 用于第一组的第一探针和第二组的第一探针。 本公开涉及在第一和第二组探针中的每一个中包括多个探针的组合物，其中每组中的探针在一个，两个或三个LNA随机位置上不同。 此外，本公开涉及通过上述探针检测基因组变体的方法。

    STABILIZER SYSTEMS FOR POLYMERS CONTAINING HALOGEN
    6.
    发明申请
    STABILIZER SYSTEMS FOR POLYMERS CONTAINING HALOGEN 审中-公开
    含有卤素聚合物的稳定剂体系

    公开(公告)号：US20110275747A1

    公开(公告)日：2011-11-10

    申请号：US12774934

    申请日：2010-05-06

    申请人： Peter Hacker ,  Reinhard Beck

    发明人： Peter Hacker ,  Reinhard Beck

    IPC分类号： C08K5/17 ,  C08K5/21 ,  C09K3/00

    CPC分类号： C08K5/16 ,  C08K3/26 ,  C08K5/17 ,  C08K5/21 ,  C08K5/3462 ,  C08K2003/265 ,  C08K2201/014 ,  C08L27/06

    摘要： The present invention relates to a stabilizer system for polymers containing halogen, comprising an alkaline earth metal double carbonate of the formula (A) (M1O)m*(M2O)n−m*(CO2)o*(H2O)p  (A) where M1 and M2=various alkaline earth metals; m=from 0.9 to 1.1; n=from 1.9 to 2.1 and p=from 0 to 2.1; or n=from 3.9 to 4.1, and p=from 0 to 4.1; o=from 0 to 1.1 and at least one of the compounds selected from the group consisting of (B) and (C), where (B) is at least one nitrogen-containing organic compound selected from the group consisting of (B1) and (B2), where (B1) is a tert-alkanolamine and (B2) is an enaminone or a urea, and (C) is an alkaline earth metal aluminohydroxocarbonate of the formula (C) (M1−xZnx)yAl2(OH)4+2yCO3*zH2O  (C) where M=magnesium or/and calcium; x=from 0 to 0.5; y=from 2 to 8, and z=from 0 to 12. The present invention further relates to compositions and articles comprising said stabilizer systems, and to processes for stabilizing a polymer containing halogen.

    摘要翻译： 本发明涉及含卤素聚合物的稳定剂体系，其包含式（A）（M1O）m *（M2O）n-m *（CO2）o *（H2O）p（A）的碱土金属双重碳酸酯， 其中M1和M2 =各种碱土金属; m = 0.9〜1.1; n = 1.9〜2.1，p = 0〜2.1; 或n = 3.9〜4.1，p = 0〜4.1; （B）和（C）中的至少一种化合物，其中（B）为选自（B1）和（B）中的至少一种含氮有机化合物， （B2），其中（B1）为叔链烷醇胺，（B2）为烯胺或脲，（C）为式（C）（M1-xZnx）yAl2（OH）4的碱土金属铝氧基碳酸酯 + 2yCO3 * zH2O（C）其中M =镁或/和钙; x =从0到0.5; y = 2至8，z = 0至12.本发明还涉及包含所述稳定剂体系的组合物和制品，以及用于稳定含卤素聚合物的方法。