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公开(公告)号：US09045403B2
公开(公告)日：2015-06-02
申请号：US13779568
申请日：2013-02-27
发明人： Hiroaki Serizawa , Ankush B. Argade , Akash Datwani , Natalie Spencer , Yonghua Pan , Florian Ermini
IPC分类号： C07C49/203 , C07C69/145 , C07C69/02 , C07C69/24 , C07C69/743 , C07C69/74 , C07C69/75 , C07C309/66 , C07C309/73 , C07C333/04 , C07C333/06 , C07C333/08 , C07D211/26 , C07D295/13 , A61K31/185 , A61K31/13 , C07C69/608 , C07C69/587 , C07C211/08 , C07C33/02 , C07C271/22 , C07C271/30 , C07C69/92 , C07C69/007 , C07C49/21 , C07D263/38 , C07C47/21 , C07C49/647 , C07C33/14 , C07C271/12 , C07C69/738 , C07C69/76 , C07C57/66 , C07C69/757 , C07C57/03 , C07C49/557 , C07D307/46 , C07C333/10 , C07C205/57 , C07C211/35 , C07C211/38 , C07C217/08 , C07D271/10 , C07D413/04 , C07C271/28 , C07D213/75 , C07D307/52 , C07D263/32 , C07C49/255 , C07C251/60 , C07C251/40 , C07C271/24 , A01N37/00
CPC分类号： C07C49/203 , C07C33/02 , C07C33/14 , C07C47/21 , C07C49/21 , C07C49/255 , C07C49/557 , C07C49/647 , C07C57/03 , C07C57/66 , C07C69/007 , C07C69/02 , C07C69/145 , C07C69/24 , C07C69/587 , C07C69/608 , C07C69/738 , C07C69/74 , C07C69/743 , C07C69/75 , C07C69/757 , C07C69/76 , C07C69/92 , C07C205/57 , C07C211/08 , C07C211/35 , C07C211/38 , C07C217/08 , C07C251/40 , C07C251/60 , C07C271/12 , C07C271/22 , C07C271/24 , C07C271/28 , C07C271/30 , C07C309/66 , C07C309/73 , C07C333/04 , C07C333/06 , C07C333/08 , C07C333/10 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/42 , C07C2603/18 , C07C2603/74 , C07D211/26 , C07D213/75 , C07D263/32 , C07D263/38 , C07D271/10 , C07D295/13 , C07D307/46 , C07D307/52 , C07D413/04
摘要： This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.
摘要翻译： 本发明涉及香叶基香叶基丙酮（GGA）衍生物以及GGA，其异构体和GGA衍生物在抑制神经死亡，增加神经活性，增加轴突生长和细胞活力的方法中的用途，以及提高GGA受试者的存活率 或GGA衍生物。
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公开(公告)号：US20130296323A1
公开(公告)日：2013-11-07
申请号：US13779568
申请日：2013-02-27
发明人： Hiroaki Serizawa , Ankush B. Argade , Akash Datwani , Natalie Spencer , Yonghua Pan , Florian Ermini
IPC分类号： C07C49/203 , C07C69/02 , C07C69/24 , C07C69/743 , C07C69/74 , C07D295/13 , C07C309/66 , C07C309/73 , C07C333/04 , C07C333/06 , C07C333/08 , C07D211/26 , C07C69/145 , C07C69/75
CPC分类号： C07C49/203 , C07C33/02 , C07C33/14 , C07C47/21 , C07C49/21 , C07C49/255 , C07C49/557 , C07C49/647 , C07C57/03 , C07C57/66 , C07C69/007 , C07C69/02 , C07C69/145 , C07C69/24 , C07C69/587 , C07C69/608 , C07C69/738 , C07C69/74 , C07C69/743 , C07C69/75 , C07C69/757 , C07C69/76 , C07C69/92 , C07C205/57 , C07C211/08 , C07C211/35 , C07C211/38 , C07C217/08 , C07C251/40 , C07C251/60 , C07C271/12 , C07C271/22 , C07C271/24 , C07C271/28 , C07C271/30 , C07C309/66 , C07C309/73 , C07C333/04 , C07C333/06 , C07C333/08 , C07C333/10 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/42 , C07C2603/18 , C07C2603/74 , C07D211/26 , C07D213/75 , C07D263/32 , C07D263/38 , C07D271/10 , C07D295/13 , C07D307/46 , C07D307/52 , C07D413/04
摘要： This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.
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3.发明申请GGA AND GGA DERIVATIVES COMPOSITIONS THEREOF AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES INCLUDING PARALYSIS INCLUDING THEM 审中-公开GGA和GGA衍生物及其治疗神经病变疾病的方法，包括包括他们的分离公开(公告)号：US20150025077A1
公开(公告)日：2015-01-22
申请号：US14381960
申请日：2013-02-27
发明人： Hiroaki Serizawa , Ankush B. Argade , Akash Datwani , Natalie Spencer , Yonghua Pan , Florian Ermini
IPC分类号： C07C49/203 , C07C69/007 , C07C69/743 , C07D295/13 , C07C69/75 , C07C205/57 , C07D213/75 , C07D307/52 , C07C33/02 , C07C69/74
CPC分类号： C07C49/203 , C07C33/02 , C07C33/14 , C07C47/21 , C07C49/21 , C07C49/255 , C07C49/557 , C07C49/647 , C07C57/03 , C07C57/66 , C07C69/007 , C07C69/02 , C07C69/145 , C07C69/24 , C07C69/587 , C07C69/608 , C07C69/738 , C07C69/74 , C07C69/743 , C07C69/75 , C07C69/757 , C07C69/76 , C07C69/92 , C07C205/57 , C07C211/08 , C07C211/35 , C07C211/38 , C07C217/08 , C07C251/40 , C07C251/60 , C07C271/12 , C07C271/22 , C07C271/24 , C07C271/28 , C07C271/30 , C07C309/66 , C07C309/73 , C07C333/04 , C07C333/06 , C07C333/08 , C07C333/10 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/42 , C07C2603/18 , C07C2603/74 , C07D211/26 , C07D213/75 , C07D263/32 , C07D263/38 , C07D271/10 , C07D295/13 , C07D307/46 , C07D307/52 , C07D413/04
摘要： This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.
摘要翻译： 本发明涉及香叶基香叶基丙酮（GGA）衍生物以及GGA，其异构体和GGA衍生物在抑制神经死亡，增加神经活性，增加轴突生长和细胞活力的方法中的用途，以及提高GGA受试者的存活率 或GGA衍生物。
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