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公开(公告)号：US07854892B2
公开(公告)日：2010-12-21
申请号：US11744936
申请日：2007-05-07
IPC分类号： G01N35/04
CPC分类号： G01N35/04 , G01N2035/00326 , G01N2035/0415 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998
摘要： A specimen-transport module adapted for use with each of a plurality of specimen-processing instruments of a multi-instrument clinical workcell. Such module is adapted to transport individual racks of specimen-containers relative to a specimen-aspiration probe of an associated instrument in a workcell, as well as to transfer selected racks of specimen-containers to an adjacent and identical specimen-transport module associated with another clinical instrument of the workcell. Since the same transport system is used to both present specimens for aspiration and to transfer specimens between instruments, there is no need for two independent conveyances as is characteristic of the prior art. Preferably, the specimen-transport module includes a magnetic X/Y transport system that operates beneath a rack-supporting surface to advance racks in mutually perpendicular directions across a supporting surface via magnetic forces.
摘要翻译： 一种适于与多仪器临床工作单元的多个样本处理装置中的每一个一起使用的样本传送模块。 这样的模块适用于相对于工作单元中相关联的仪器的样本 - 抽吸探头运送样品容器的各个架，以及将选定的样本容器架移送到与另一个相关联的相邻和相同的样品传送模块 工作单元的临床仪器。 由于使用相同的运输系统来提供用于抽吸的样本并且在仪器之间传送样品，所以不需要两个独立的运输工具，如现有技术的特征。 优选地，样本传送模块包括磁性X / Y传送系统，其在机架支撑表面下方操作，以通过磁力跨越支撑表面在彼此垂直的方向上前进架。
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公开(公告)号：US07331474B2
公开(公告)日：2008-02-19
申请号：US10794685
申请日：2004-03-05
IPC分类号： A47B73/00
CPC分类号： G01N35/04 , B01L9/06 , G01N2035/0415 , G01N2035/0477
摘要： A magnetically-attractive specimen-container rack for use with a magnetic transport system for transporting racks of specimen-containers to or within an automated clinical instrument for analysis and/or processing. The specimen-container rack comprises a pair of U-shaped magnetically-attractive members mounted in the base section of the rack housing so that the distal ends of such members extend towards the base of the rack and terminate in a plane slightly short of the plane in which the rack is supported for movement atop a rack-supporting surface. Such members are adapted to cooperate with similarly-shaped permanent magnets carried by an X/Y-movable truck that underlies a non-magnetic rack-supporting plate. Other features of the rack include a pair of side-pockets formed in one side of the rack in the vicinity of the end walls of the rack housing, such pockets serving to receive a movably-mounted member associated with a linear drive mechanism by which the rack can be physically advanced edgewise along a linear path; and notch structure by which the rack can be releasably engaged by a movably-mounted plate which serves to lift and invert the rack to effect mixing of contained specimens.
摘要翻译： 用于磁性运输系统的磁性吸引人的样品容器架，用于将样品容器的架运送到自动化临床仪器内或其内部进行分析和/或加工。 样本容器架包括安装在齿条壳体的基部中的一对U形磁吸引件，使得这些构件的远端朝向齿条的基部延伸并且终止在稍短于平面的平面中 其中支架用于在支架表面上移动。 这种构件适于与由非磁性支架板支撑的X / Y型可移动卡车所承载的类似形状的永磁体配合。 齿条的其它特征包括在齿条壳体的端壁附近形成在齿条的一侧的一对侧口袋，这些口袋用于容纳与线性驱动机构相关联的可移动安装的构件， 机架可以沿线性路径沿边缘进行物理高级化; 以及切口结构，齿条可以通过可移动安装的板可释放地接合，该板用于提升和倒转齿条以实现所容纳的试样的混合。
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公开(公告)号：US07998409B2
公开(公告)日：2011-08-16
申请号：US11859347
申请日：2007-09-21
CPC分类号： G01N35/04 , G01N2035/00326 , G01N2035/0415 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998
摘要： A specimen-transport module adapted for use with each of a plurality of specimen-processing instruments of a multi-instrument clinical workcell. Such module is adapted to transport individual racks of specimen-containers relative to a specimen-aspiration probe of an associated instrument in a workcell, as well as to transfer selected racks of specimen-containers to an adjacent and identical specimen-transport module associated with another clinical instrument of the workcell. Since the same transport system is used to both present specimens for aspiration and to transfer specimens between instruments, there is no need for two independent conveyances as is characteristic of the prior art. Preferably, the specimen-transport module includes a magnetic X/Y transport system that operates beneath a rack-supporting surface to advance racks in mutually perpendicular directions across a supporting surface via magnetic forces.
摘要翻译： 一种适于与多仪器临床工作单元的多个样本处理装置中的每一个一起使用的样本传送模块。 这样的模块适用于相对于工作单元中相关联的仪器的样本 - 抽吸探头运送样品容器的各个架，以及将选定的样本容器架移送到与另一个相关联的相邻和相同的样品传送模块 工作单元的临床仪器。 由于使用相同的运输系统来提供用于抽吸的样本并且在仪器之间传送样品，所以不需要两个独立的运输工具，如现有技术的特征。 优选地，样本传送模块包括磁性X / Y传送系统，其在机架支撑表面下方操作，以通过磁力跨越支撑表面在彼此垂直的方向上前进架。
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公开(公告)号：US07850914B2
公开(公告)日：2010-12-14
申请号：US10794702
申请日：2004-03-05
IPC分类号： G01N35/04
CPC分类号： G01N35/04 , G01N2035/00326 , G01N2035/0415 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998
摘要： A specimen-transport module adapted for use with each of a plurality of specimen-processing instruments of a multi-instrument clinical workcell. Such module is adapted to transport individual racks of specimen-containers relative to a specimen-aspiration probe of an associated instrument in a workcell, as well as to transfer selected racks of specimen-containers to an adjacent and identical specimen-transport module associated with another clinical instrument of the workcell. Since the same transport system is used to both present specimens for aspiration and to transfer specimens between instruments, there is no need for two independent conveyances as is characteristic of the prior art. Preferably, the specimen-transport module includes a magnetic X/Y transport system that operates beneath a rack-supporting surface to advance racks in mutually perpendicular directions across a supporting surface via magnetic forces.
摘要翻译： 一种适于与多仪器临床工作单元的多个样本处理装置中的每一个一起使用的样本传送模块。 这样的模块适用于相对于工作单元中相关联的仪器的样本 - 抽吸探头运送样品容器的各个架，以及将选定的样品容器架移送到与另一个相关联的相邻和相同的样本传输模块 工作单元的临床仪器。 由于使用相同的运输系统来提供用于抽吸的样本并且在仪器之间传送样品，所以不需要两个独立的运输工具，如现有技术的特征。 优选地，样本传送模块包括磁性X / Y传送系统，其在机架支撑表面下方操作，以通过磁力跨越支撑表面在彼此垂直的方向上前进架。
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5.发明授权公开(公告)号：US07661326B2
公开(公告)日：2010-02-16
申请号：US11553107
申请日：2006-10-26
申请人： William W. Li , William J. Casey , Craig R. Veiner , Carlos R. Gonzalez , Jose M. Cano , Roberto Del Valle , Santiago Galvez
发明人： William W. Li , William J. Casey , Craig R. Veiner , Carlos R. Gonzalez , Jose M. Cano , Roberto Del Valle , Santiago Galvez
IPC分类号： G01N1/00
CPC分类号： G01N35/1097
摘要： Apparatus for aspirating and dispensing liquid samples in an analytical instrument, e.g., a hematology instrument, includes a liquid-sampling valve that, while operating to segment and position for dispensing one or more precise volumes of a liquid sample that has been aspirated into the valve by a pump, simultaneously enables the apparatus to be operated in an aspirate/dispense (suck-and-spit) mode in which a liquid sample can be selectively driven through the valve in opposite directions by a pump, e.g., a syringe pump.
摘要翻译： 用于在分析仪器（例如血液仪器）中抽吸和分配液体样品的装置包括液体取样阀，该液体采样阀在操作以分段和定位以分配一个或多个精确体积的已被吸入阀中的液体样品 通过泵同时使装置能够以抽吸/分配（吸吮）模式操作，其中液体样品可以通过泵（例如注射泵）在相反方向上被选择性地驱动通过阀。
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6.发明申请公开(公告)号：US20080098828A1
公开(公告)日：2008-05-01
申请号：US11553107
申请日：2006-10-26
申请人： William W. Li , William J. Casey , Craig R. Veiner , Carlos R. Gonzalez , Jose M. Cano , Roberto Del Valle , Santiago Galvez
发明人： William W. Li , William J. Casey , Craig R. Veiner , Carlos R. Gonzalez , Jose M. Cano , Roberto Del Valle , Santiago Galvez
IPC分类号： G01N1/00
CPC分类号： G01N35/1097
摘要： Apparatus for aspirating and dispensing liquid samples in an analytical instrument, e.g., a hematology instrument, includes a liquid-sampling valve that, while operating to segment and position for dispensing one or more precise volumes of a liquid sample that has been aspirated into the valve by a pump, simultaneously enables the apparatus to be operated in an aspirate/dispense (suck-and-spit) mode in which a liquid sample can be selectively driven through the valve in opposite directions by a pump, e.g., a syringe pump.
摘要翻译： 用于在分析仪器（例如血液仪器）中抽吸和分配液体样品的装置包括液体取样阀，该液体采样阀在操作以分段和定位以分配一个或多个精确体积的已被吸入阀中的液体样品 通过泵同时使装置能够以抽吸/分配（吸吮）模式操作，其中液体样品可以通过泵（例如注射泵）在相反方向上被选择性地驱动通过阀。
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公开(公告)号：US20080008624A1
公开(公告)日：2008-01-10
申请号：US11859347
申请日：2007-09-21
申请人： Craig Veiner , Frank Tappen , Roberto Del Valle
发明人： Craig Veiner , Frank Tappen , Roberto Del Valle
IPC分类号： G01N35/10
CPC分类号： G01N35/04 , G01N2035/00326 , G01N2035/0415 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998
摘要： A specimen-transport module adapted for use with each of a plurality of specimen-processing instruments of a multi-instrument clinical workcell. Such module is adapted to transport individual racks of specimen-containers relative to a specimen-aspiration probe of an associated instrument in a workcell, as well as to transfer selected racks of specimen-containers to an adjacent and identical specimen-transport module associated with another clinical instrument of the workcell. Since the same transport system is used to both present specimens for aspiration and to transfer specimens between instruments, there is no need for two independent conveyances as is characteristic of the prior art. Preferably, the specimen-transport module includes a magnetic X/Y transport system that operates beneath a rack-supporting surface to advance racks in mutually perpendicular directions across a supporting surface via magnetic forces.
摘要翻译： 一种适于与多仪器临床工作单元的多个样本处理装置中的每一个一起使用的样本传送模块。 这样的模块适用于相对于工作单元中相关联的仪器的样本 - 抽吸探头运送样品容器的各个架，以及将选定的样本容器架移送到与另一个相关联的相邻和相同的样品传送模块 工作单元的临床仪器。 由于使用相同的运输系统来提供用于抽吸的样本并且在仪器之间传送样品，所以不需要两个独立的运输工具，如现有技术的特征。 优选地，样本传送模块包括磁性X / Y传送系统，其在机架支撑表面下方操作，以通过磁力跨越支撑表面在彼此垂直的方向上前进架。
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公开(公告)号：US20050196320A1
公开(公告)日：2005-09-08
申请号：US10794702
申请日：2004-03-05
申请人： Craig Veiner , Frank Tappen , Roberto Del Valle
发明人： Craig Veiner , Frank Tappen , Roberto Del Valle
IPC分类号： G01N35/00
CPC分类号： G01N35/04 , G01N2035/00326 , G01N2035/0415 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998
摘要： A specimen-transport module adapted for use with each of a plurality of specimen-processing instruments of a multi-instrument clinical workcell. Such module is adapted to transport individual racks of specimen-containers relative to a specimen-aspiration probe of an associated instrument in a workcell, as well as to transfer selected racks of specimen-containers to an adjacent and identical specimen-transport module associated with another clinical instrument of the workcell. Since the same transport system is used to both present specimens for aspiration and to transfer specimens between instruments, there is no need for two independent conveyances as is characteristic of the prior art. Preferably, the specimen-transport module includes a magnetic X/Y transport system that operates beneath a rack-supporting surface to advance racks in mutually perpendicular directions across a supporting surface via magnetic forces.
摘要翻译： 一种适于与多仪器临床工作单元的多个样本处理装置中的每一个一起使用的样本传送模块。 这样的模块适用于相对于工作单元中相关联的仪器的样本 - 抽吸探头运送样品容器的各个架，以及将选定的样品容器架移送到与另一个相关联的相邻和相同的样本传输模块 工作单元的临床仪器。 由于使用相同的运输系统来提供用于抽吸的样本并且在仪器之间传送样品，所以不需要两个独立的运输工具，如现有技术的特征。 优选地，样本传送模块包括磁性X / Y传送系统，其在机架支撑表面下方操作，以通过磁力跨越支撑表面在彼此垂直的方向上前进架。
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公开(公告)号：US20050194333A1
公开(公告)日：2005-09-08
申请号：US10794685
申请日：2004-03-05
申请人： Craig Veiner , Frank Tappen , Roberto Del Valle , Richard Marquis
发明人： Craig Veiner , Frank Tappen , Roberto Del Valle , Richard Marquis
IPC分类号： A47B73/00
CPC分类号： G01N35/04 , B01L9/06 , G01N2035/0415 , G01N2035/0477
摘要： A magnetically-attractive specimen-container rack for use with a magnetic transport system for transporting racks of specimen-containers to or within an automated clinical instrument for analysis and/or processing. The specimen-container rack comprises a pair of U-shaped magnetically-attractive members mounted in the base section of the rack housing so that the distal ends of such members extend towards the base of the rack and terminate in a plane slightly short of the plane in which the rack is supported for movement atop a rack-supporting surface. Such members are adapted to cooperate with similarly-shaped permanent magnets carried by an X/Y-movable truck that underlies a non-magnetic rack-supporting plate. Other features of the rack include a pair of side-pockets formed in one side of the rack in the vicinity of the end walls of the rack housing, such pockets serving to receive a movably-mounted member associated with a linear drive mechanism by which the rack can be physically advanced edgewise along a linear path; and notch structure by which the rack can be releasably engaged by a movably-mounted plate which serves to lift and invert the rack to effect mixing of contained specimens.
摘要翻译： 用于磁性运输系统的磁性吸引人的样品容器架，用于将样品容器的架运送到自动化临床仪器内或其内部进行分析和/或加工。 样本容器架包括安装在齿条壳体的基部中的一对U形磁吸引件，使得这些构件的远端朝向齿条的基部延伸并且终止于稍微短于平面的平面中 其中支架用于在支架表面上移动。 这种构件适于与由非磁性支架板支撑的X / Y型可移动卡车所承载的类似形状的永磁体配合。 齿条的其它特征包括在齿条壳体的端壁附近形成在齿条的一侧的一对侧口袋，这些口袋用于容纳与线性驱动机构相关联的可移动安装的构件， 机架可以沿线性路径沿边缘进行物理高级化; 以及切口结构，齿条可以通过可移动安装的板可释放地接合，该板用于提升和倒转齿条以实现所容纳的试样的混合。
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公开(公告)号：US20070105230A1
公开(公告)日：2007-05-10
申请号：US11270859
申请日：2005-11-09
申请人： Carlos Perez , Lidice Lopez , Mark Wells , Joaquin Ibanez , Eileen Landrum , Roberto Del Valle , Santiago Galvez
发明人： Carlos Perez , Lidice Lopez , Mark Wells , Joaquin Ibanez , Eileen Landrum , Roberto Del Valle , Santiago Galvez
IPC分类号： G01N33/48
CPC分类号： G01N33/80 , Y10T436/10 , Y10T436/101666 , Y10T436/107497 , Y10T436/25 , Y10T436/25125
摘要： A method for discriminating and quantifying platelets within an analyzed blood sample involves initially diluting the blood sample with a ghosting reagent that causes a change in the index of refraction of the cell. Owing to the change in the index of refraction, light scattered from the ghosted red blood cells will be substantially reduced relative to light scattered from platelets. This results in locations of platelets within a scatterplot of the analyzed blood sample to fall within a region distinguishable from those containing normal red blood cells, fragmented red blood cells, and microcytic red blood cells.
摘要翻译： 在分析的血液样品中鉴别和定量血小板的方法包括首先用引起细胞折射率变化的重影试剂稀释血液样品。 由于折射率的变化，相对于从血小板散射的光，从重影的红细胞散射的光将显着降低。 这导致血小板在分析的血液样品的散点图内的位置落入与含有正常红细胞，碎片红细胞和微红细胞的区域区分开的区域内。
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