公开(公告)号：US20220161527A1

公开(公告)日：2022-05-26

申请号：US17431015

申请日：2019-12-13

Applicant: DAIKIN INDUSTRIES, LTD. ,  DAIKIN AMERICA, INC.

Inventor： Kozue KOMAZAWA ,  Kyle BRUNDIN ,  Yuuki KUWAJIMA ,  Yosuke NISHIMURA ,  Steve MARICONTI ,  Takeshi INABA

IPC: B32B25/08 ,  B32B25/18 ,  B32B27/32 ,  B32B25/02 ,  B32B1/08 ,  B32B27/26 ,  B32B27/30

Abstract: Adding silica particles having specified collective characteristics to a fluororubber formulation enhances direct adhesion between the fluororubber formulation and a copolymer upon curing. Specifically, as measured before being mixed into the fluororubber formulation, the silica particles have an average value of the product “(particle size)×(circularity)” that is 17.5 nm or higher and 500 μm or lower. The silica particles may also have an average particle size of between 25.0 nm inclusive and 500 μm inclusive, and an average circularity of 0.80 or higher. Alternatively, as measured after being incorporated into the fluororubber formulation and then cured, the silica particles have an apparent average value of the product “(particle size)×(circularity)” that is 32.0 nm or higher and 500 μm or lower. The silica particles may also have an apparent average particle size of between 40.0 nm inclusive and 500 μm inclusive as measured after being incorporated into the fluororubber formulation and then cured.

公开(公告)号：US20160288461A1

公开(公告)日：2016-10-06

申请号：US15034214

申请日：2014-11-12

Applicant: DAIKIN INDUSTRIES, LTD.

Inventor： Yuuki KUWAJIMA ,  Shoji FUKUOKA ,  Kozue KOMAZAWA ,  Mayuko TAEDA ,  Junpei TERADA

IPC: B32B25/08 ,  C08K5/14 ,  B32B27/30 ,  C08K5/29 ,  B32B25/14 ,  B32B27/32

Abstract: The present invention aims to provide a laminate in which a fluororesin layer and a fluororubber layer are firmly bonded even when the fluororesin layer contains a fluororesin having excellently low fuel permeability. The present invention relates to a laminate including a fluororubber layer (A) and a fluororesin layer (B) stacked on the fluororubber layer (A). The fluororubber layer (A) is a layer formed from a fluororubber composition. The fluororubber composition contains a fluororubber (a1) and a basic multifunctional compound having at least two nitrogen atoms in the molecule with a distance between the nitrogen atoms in the molecule of 5.70 Å or greater. The fluororubber (a1) has an absorption coefficient at 1720 cm−1, determined after being brought into contact with triethyl amine, of 0.35 or lower. The fluororesin layer (B) is formed from a fluororesin (b1) having a fuel permeability coefficient of 2.0 g·mm/m2/day or lower.

Abstract translation: 本发明的目的在于提供一种即使在氟树脂层含有具有优异的低燃料透过性的氟树脂的情况下也能够使氟树脂层和氟橡胶层牢固结合的层压体。 本发明涉及层叠在氟橡胶层（A）上的氟橡胶层（A）和氟树脂层（B）的层叠体。 氟橡胶层（A）是由氟橡胶组合物形成的层。 氟橡胶组合物含有氟橡胶（a1）和分子中具有至少两个氮原子的碱性多官能化合物，分子中的氮原子之间的距离为5.70以上。 氟橡胶（a1）在与三乙胺接触后测定的在1720cm -1处的吸收系数为0.35以下。 氟树脂层（B）由燃料透过系数为2.0g·mm / m 2 /天以下的氟树脂（b1）形成。

公开(公告)号：US20190161726A1

公开(公告)日：2019-05-30

申请号：US16321265

申请日：2017-07-28

Applicant: DAIKIN INDUSTRIES, LTD. ,  KYOTO UNIVERSITY

Inventor： Kozue KOMAZAWA ,  Tatsuya HIGUCHI ,  Shin KANEKO ,  Yutaka YASUI

IPC: C12N5/0735 ,  C12M1/00 ,  C09D127/18 ,  C08F14/26 ,  C08F214/26 ,  C08F214/28 ,  C12N5/074

Abstract: A method for producing differentiated cells from pluripotent stem cells by an embryoid body (EB) method, including the steps of: (1) culturing pluripotent stem cells by using a culture bag having a perfluoropolymer on its inner surface to thereby form an embryoid body; and (2) inducing differentiation of the pluripotent stem cells contained in the embryoid body obtained in step (1) to thereby obtain differentiated cells.

公开(公告)号：US20180201890A1

公开(公告)日：2018-07-19

申请号：US15743913

申请日：2016-07-14

Applicant: DAIKIN INDUSTRIES, LTD. ,  OTSUKA PHARMACEUTICAL FACTORY, INC.

Inventor： Tatsuya HIGUCHI ,  Kozue KOMAZAWA ,  Yoshiko MOHARA ,  Takayuki DEMPO ,  Masuhiro NISHIMURA

IPC: C12M1/00 ,  C12N5/0775 ,  C09D127/18 ,  C09D127/20 ,  C09D129/10 ,  A61K35/28

CPC classification number: C12M23/20 ,  A61K35/28 ,  C09D127/18 ,  C09D127/20 ,  C09D129/10 ,  C12M23/14 ,  C12N5/0663

Abstract: When mammal cells are administered by using a container whose surface in contact with the mammal cells is formed of a fluororesin material at least partially having a —CF3 terminal group or a container whose surface in contact with the mammal cells is formed of a fluororesin material having a total number of non-fluorinated group terminals and —CF2H group terminals in the fluororesin of 70 or less per 1×106 carbon atoms, or mammal cells are stored or cultured in such a container, the cell adhesion on the container inner surface and the cell survival rate reduction can effectively be suppressed. Therefore, by using these containers, a mammal cell-containing liquid having a high concentration and a high proportion of living cells can be administered, stored or prepared, which contributes to regenerative medicine using the mammal cell-containing liquid (suspension liquid).