公开(公告)号：US20190224081A1

公开(公告)日：2019-07-25

申请号：US15898933

申请日：2018-02-19

申请人： DENTSPLY SIRONA INC.

发明人： Hui LU ,  Xiaoming JIN ,  Joachim E. KLEE ,  Bernard KOLTISKO

IPC分类号： A61K6/083 ,  A61K6/00 ,  C07D295/24

摘要： A method of forming a dental composite includes photopolymerizing a dental composition. The dental composition includes a free-radically polymerizable (meth)acrylate resin, 75 percent by weight or greater of filler particles, and about 0.005 percent to about 5 percent by weight of at least one polymerizable stable radical. The photopolymerizing forms the dental composite such that the dental composite has a flexural modulus of about 9500 MPa or greater and the polymerizable stable radical reduces shrinkage stress of the dental composite caused by the photopolymerizing by 10% or greater. A method of forming a dental composite composition includes combining a free-radically polymerizable (meth)acrylate resin, 75 percent by weight or greater of filler particles, and about 0.005 percent to about 5 percent by weight of at least one polymerizable stable radical to form the dental composite composition.

公开(公告)号：US20170280725A1

公开(公告)日：2017-10-05

申请号：US15476005

申请日：2017-03-31

申请人： DENTSPLY SIRONA INC.

发明人： Xiaoming JIN ,  Hui LU ,  Christopher DAMIEN ,  Bernard KOLTISKO

IPC分类号： A01N57/04 ,  A61K6/083 ,  A61K6/00 ,  A01N43/50 ,  A01N25/10 ,  A23L33/16 ,  A23L2/52 ,  F16L58/04 ,  A61C5/50 ,  A61C5/70 ,  A61C7/08 ,  A61C7/16 ,  A61C8/00 ,  A61C9/00 ,  A61C13/00 ,  A61C19/06 ,  A61B17/84 ,  A61B17/86 ,  A61B17/06 ,  A61F2/06 ,  A61F2/16 ,  A61B42/10 ,  A61B46/00 ,  A61F2/00 ,  A61F6/04 ,  A61F6/14 ,  A61F13/20 ,  A61F13/36 ,  A61F6/08 ,  A61F2/24 ,  A61M16/00 ,  A61M25/00 ,  A61M5/14 ,  A61M27/00 ,  A01N25/08

CPC分类号： A01N57/04 ,  A01N25/08 ,  A01N25/10 ,  A01N33/12 ,  A01N43/50 ,  A01N57/34 ,  A23L2/52 ,  A23L33/16 ,  A23V2002/00 ,  A61B17/06166 ,  A61B17/848 ,  A61B17/86 ,  A61B42/10 ,  A61B46/40 ,  A61B2017/00889 ,  A61B2017/681 ,  A61C5/50 ,  A61C5/70 ,  A61C7/08 ,  A61C7/16 ,  A61C8/0013 ,  A61C8/0048 ,  A61C9/00 ,  A61C13/0004 ,  A61C13/0022 ,  A61C19/066 ,  A61F2/0063 ,  A61F2/06 ,  A61F2/16 ,  A61F2/24 ,  A61F6/04 ,  A61F6/08 ,  A61F6/14 ,  A61F13/2051 ,  A61F13/36 ,  A61F2013/00089 ,  A61K6/0017 ,  A61K6/083 ,  A61K8/416 ,  A61K8/55 ,  A61K8/8158 ,  A61K8/817 ,  A61K8/8188 ,  A61K8/898 ,  A61M5/14 ,  A61M16/0057 ,  A61M25/0043 ,  A61M27/002 ,  A61M2025/0056 ,  A61Q11/00 ,  F16L58/04

摘要： Compositions and methods for inhibiting and interrupting biofilm formation, and for destabilizing established biofilms are provided, the novel compositions including polymeric resins and monomeric non-polymerizable and polymerizable resins. More particularly, the compositions and methods enable the protection and removal of biofilms from surfaces in the context of medical, consumer, domestic, food service, environmental and industrial applications, where the effects constitute beneficial and desirable biofilm attenuating activity.

公开(公告)号：US20230022721A1

公开(公告)日：2023-01-26

申请号：US17941323

申请日：2022-09-09

申请人： DENTSPLY SIRONA Inc.

发明人： Xiaoming JIN ,  Hui LU ,  Christopher DAMIEN ,  Bernard KOLTISKO

IPC分类号： A01N57/04 ,  A61K8/81 ,  A61Q11/00 ,  A01N33/12 ,  A01N57/34 ,  A61K8/55 ,  A61K8/898 ,  A61K8/41 ,  A61K6/20 ,  A61K6/887 ,  A61B42/10 ,  A61B46/00 ,  A23L33/16 ,  A61C5/70 ,  A61C5/50 ,  A01N25/08 ,  A01N25/10 ,  A01N43/50 ,  A23L2/52 ,  A61B17/06 ,  A61B17/84 ,  A61B17/86 ,  A61C7/08 ,  A61C7/16 ,  A61C8/00 ,  A61C9/00 ,  A61C13/00 ,  A61C19/06 ,  A61F2/00 ,  A61F2/06 ,  A61F2/16 ,  A61F2/24 ,  A61F6/04 ,  A61F6/08 ,  A61F6/14 ,  A61F13/20 ,  A61F13/36 ,  A61M5/14 ,  A61M16/00 ,  A61M25/00 ,  A61M27/00 ,  F16L58/04

摘要： Compositions and methods for inhibiting and interrupting biofilm formation, and for destabilizing established biofilms are provided, the novel compositions including polymeric resins and monomeric non-polymerizable and polymerizable resins. More particularly, the compositions and methods enable the protection and removal of biofilms from surfaces in the context of medical, consumer, domestic, food service, environmental and industrial applications, where the effects constitute beneficial and desirable biofilm attenuating activity.