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公开(公告)号:US20240355612A1
公开(公告)日:2024-10-24
申请号:US18685356
申请日:2022-08-23
发明人: David M. COX , Manuel FAUR , Mircea GUNA , Yang KANG , Andrei SONOC
CPC分类号: H01J49/4215 , H01J49/004
摘要: In one aspect, an ion filter for use in a mass spectrometer is disclosed, which includes a plurality of rods arranged in a multipole configuration to provide a passageway through which ions can travel, said plurality of rods being configured for application of RF voltages thereto to provide an electromagnetic field within the passageway for providing radial confinement of the ions and further configured for application of a DC voltage thereto. At least two pairs of auxiliary electrodes are interspersed between the plurality of rods and are configured for application of a DC bias voltage with one polarity to one of said pairs and a DC bias voltage with an opposite polarity to the other one of said pairs to provide a DC potential difference between the auxiliary electrodes and the plurality of rods.
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公开(公告)号:US20240234123A1
公开(公告)日:2024-07-11
申请号:US18037582
申请日:2021-11-17
发明人: Bruce COLLINGS , James HAGER , Yang KANG , Bradley B. SCHNEIDER
CPC分类号: H01J49/4215 , H01J49/0031 , H01J49/24 , H01J49/0086
摘要: A mass spectrometer comprises a first mass filter for receiving a plurality of ions and having a transmission bandwidth configured to allow transmission of ions having m/z ratios within a desired range, and a second mass filter that is disposed downstream of the first mass filter for selecting ions having a target m/z value within a transmission window thereof for mass analysis. The transmission bandwidth of the first mass filter encompasses at least two m/z ratios of interest such that one of said m/z ratios corresponds to said target m/z value within the transmission window of said second mass filter.
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公开(公告)号:US20240355611A1
公开(公告)日:2024-10-24
申请号:US18685534
申请日:2022-08-23
发明人: David M. COX , Mircea GUNA , Yang KANG , Mircea MANOLESCU , Andrei SONOC
IPC分类号: H01J49/42
CPC分类号: H01J49/421
摘要: An ion mass filter for use in a mass spectrometer is disclosed, which includes a plurality of rods arranged in a multipole configuration to provide a passageway through which ions can travel, said plurality of rods being configured for application of RF voltages thereto to generate an electromagnetic field within the passageway for providing radial confinement of the ions and further configured for application of a DC voltage thereto, and at least two pairs of auxiliary electrodes interspersed between the plurality of multipole rods, where one pair forms a first pole of the auxiliary electrodes and the other pair forms a second pole of the auxiliary electrodes. A controller can provide one or more control signals to the DC voltage source so as to switch the polarity of the DC voltage differential between the two poles according to a predefined criterion.
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4.
公开(公告)号:US20240175846A1
公开(公告)日:2024-05-30
申请号:US18283318
申请日:2022-03-22
发明人: Thomas COVEY , Yang KANG , Bradley B. SCHNEIDER
IPC分类号: G01N27/624 , G01N27/623 , H01J49/24
CPC分类号: G01N27/624 , G01N27/623 , H01J49/24
摘要: Methods and systems for performing differential mobility spectrometry are provided herein. Systems and methods in accordance with various aspects of the present teachings provide differential mobility separation at drift gas volumetric flow rates greater than about 10 L/min, which are substantially higher than those previously reported and conventionally used in DMS-based analyses.
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公开(公告)号:US20240087870A1
公开(公告)日:2024-03-14
申请号:US18273914
申请日:2022-01-21
IPC分类号: H01J49/24
CPC分类号: H01J49/24
摘要: In one aspect, an ion guide for use in a mass spectrometry system is disclosed, which comprises an inlet for receiving a plurality of ions entrained in a gas flow, and a plurality of rods arranged in a multipole configuration so as to provide a passageway through which the received ions can traverse. At least one of the rods is configured for application of a DC and/or an RF voltage thereto for generating an electromagnetic field within the passageway suitable for focusing the ions, and a controller configured to maintain an operational pressure of the ion guide within a predefined range.
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