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公开(公告)号：US20150143588A1
公开(公告)日：2015-05-21
申请号：US14531710
申请日：2014-11-03
Applicant: DOW AGROSCIENCES LLC
Inventor： Lakshmi SASTRY-DENT , Steven L. EVANS , Ryan C. BLUE , Zehui CAO
IPC: C12N15/82
CPC classification number: C12N15/8213 , C12N15/8209 , C12N15/8212 , C12N15/8275
Abstract: A universal donor polynucleotide is described that can be inserted at targeted locations in plant genomes to facilitate rapid and high throughput integration of a donor molecule within a specific genomic location.
Abstract translation: 描述了可以在植物基因组中的靶位置插入通用供体多核苷酸，以促进供体分子在特定基因组位置内的快速和高通量整合。
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公开(公告)号：US20150128310A1
公开(公告)日：2015-05-07
申请号：US14531739
申请日：2014-11-03
Applicant: Dow AgroSciences LLC
Inventor： Lakshmi SASTRY-DENT , Zehui CAO , Shreedharan SRIRAM , Steven R. WEBB , Debra L. CAMPER
CPC classification number: C12N15/8213 , A01H5/10 , C12N15/8243 , C12N15/8273 , C12N15/8274 , C12N15/8286
Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.
Abstract translation: 如本文所公开的，已经鉴定了代表用于靶向插入外源序列的最佳位点的来自玉米植物的最佳天然基因座。
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公开(公告)号：US20210230617A1
公开(公告)日：2021-07-29
申请号：US17224659
申请日：2021-04-07
Applicant: DOW AGROSCIENCES LLC
Inventor： Lakshmi SASTRY-DENT , Zehui CAO , Shreedharan SRIRAM , Steven R. WEBB , Debra L. CAMPER , W. Michael AINLEY
Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.
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公开(公告)号：US20190194674A1
公开(公告)日：2019-06-27
申请号：US16263133
申请日：2019-01-31
Applicant: DOW AGROSCIENCES LLC
Inventor： Lakshmi SASTRY-DENT , Zehui CAO , Shreedharan SRIRAM , Steven R. WEBB , Debra L. CAMPER , Navin ELANGO
CPC classification number: C12N15/8213 , A01H5/10 , C12N15/8243 , C12N15/8273 , C12N15/8274 , C12N15/8286
Abstract: As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.
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公开(公告)号：US20190136265A1
公开(公告)日：2019-05-09
申请号：US16246864
申请日：2019-01-14
Applicant: Dow AgroSciences LLC
Inventor： Lakshmi SASTRY-DENT , Zehui CAO , Shreedharan SRIRAM , Steven R. WEBB , Debra L. CAMPER
Abstract: As disclosed herein, optimal native genomic loci have been identified in dicot plants, such as soybean plants, that represent best sites for targeted insertion of exogenous sequences.
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Patent Agency Ranking
公开(公告)号：US20180142250A1
公开(公告)日：2018-05-24
申请号：US15867770
申请日：2018-01-11
Applicant: DOW AGROSCIENCES LLC
Inventor： Lakshmi SASTRY-DENT , Zehui CAO , Shreedharan SRIRAM , Steven R. WEBB , Debra L. CAMPER , W. Michael AINLEY
CPC classification number: C12N15/8213 , A01H5/10 , C12N15/8243 , C12N15/8273 , C12N15/8274 , C12N15/8286
Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.
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公开(公告)号：US20150128307A1
公开(公告)日：2015-05-07
申请号：US14531732
申请日：2014-11-03
Applicant: Dow AgroSciences LLC
Inventor： Lakshmi SASTRY-DENT , Zehui CAO , Shreedharan SRIRAM , Steven R. WEBB , Debra L. CAMPER
CPC classification number: C12N15/902 , C12N15/8213
Abstract: As disclosed herein, optimal native genomic loci have been identified in dicot plants, such as soybean plants, that represent best sites for targeted insertion of exogenous sequences.
Abstract translation: 如本文所公开的，在双子叶植物（例如大豆植物）中鉴定出最佳的天然基因组基因座，其表示用于靶向插入外源序列的最佳位点。
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公开(公告)号：US20180010200A1
公开(公告)日：2018-01-11
申请号：US15705447
申请日：2017-09-15
Applicant: DOW AGROSCIENCES LLC
Inventor： Lakshmi SASTRY-DENT , W. Michael AINLEY , Jayakumar P. SAMUEL , Zehui CAO , Liu SHEN , Cristie M. DEWES
IPC: C12Q1/68
CPC classification number: C12Q1/6895
Abstract: The present disclosure provides a system and methods for detecting and identifying plant events that contain donor sequences inserted precisely into a targeted genomic loci, and plants and plant cells comprising such targeted genomic loci. The method comprises the steps of amplifying a genomic DNA with a first round of PCR to produce an amplicon from donor sequences inserted in the reverse orientation, wherein the production of the amplicon indicates the presence of the site specific integration event.
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公开(公告)号：US20170044558A1
公开(公告)日：2017-02-16
申请号：US15338888
申请日：2016-10-31
Applicant: DOW AGROSCIENCES LLC
Inventor： W. Michael AINLEY , James W. BING , David R. CORBIN , Steven L. EVANS , Joseph F. PETOLINO , Lakshmi SASTRY-DENT , Steven A. THOMPSON , Steven R. WEBB , Mary E. WELTER , Ning ZHOU
CPC classification number: C12N15/8213 , C12N9/1241 , C12Y207/07047
Abstract: The present invention claims methods for the stable integration of exogenous DNA into a specific locus, E32, in the maize genome through the use of zinc finger nucleases. Maize plants and plant parts that were transformed by the methods of the invention are claimed. The invention is useful for creating desirable traits such as herbicide resistance, herbicide tolerance, insect resistance, insect tolerance, disease resistance, disease tolerance, stress tolerance, and stress resistance in maize The E32 locus represents a superior site for inserting foreign genes because native agronomic phenotypes are not disturbed.
Abstract translation: 本发明要求通过使用锌指核酸酶将外源DNA稳定整合到玉米基因组中的特定基因座E32的方法。 要求保护通过本发明方法转化的玉米植物和植物部分。 本发明可用于产生所需的性状如除草剂抗性，除草剂耐受性，抗虫性，抗虫性，抗病性，抗病性，胁迫耐受性和玉米中的胁迫耐受性E32基因座代表插入外源基因的优越位点，因为天然农艺 表型不受干扰。
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公开(公告)号：US20150128309A1
公开(公告)日：2015-05-07
申请号：US14531705
申请日：2014-11-03
Applicant: Dow AgroSciences LLC
Inventor： Lakshmi SASTRY-DENT , Zehui CAO , Shreedharan SRIRAM , Steven R. WEBB , Debra L. CAMPER , Navin ELANGO
CPC classification number: C12N15/8213 , A01H5/10 , C12N15/8243 , C12N15/8273 , C12N15/8274 , C12N15/8286
Abstract: As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.
Abstract translation: 如本文所公开的，在单子叶植物（例如玉米植物）中鉴定出最佳天然基因组基因座，其代表用于靶向插入外源序列的最佳位点。
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