METHODS OF FORMING STORAGE STABLE MIXTURES
    6.
    发明公开

    公开(公告)号:US20240324626A1

    公开(公告)日:2024-10-03

    申请号:US18741628

    申请日:2024-06-12

    CPC classification number: A23K20/105 A23K20/158 A23K20/24 A23K20/28 A23K50/10

    Abstract: Methods to improve retention of propanediol mononitrate and derivatives thereof in a powderous formulation comprising the propane diol mononitrate and silica include forming a uniform mixture of (i) the powderous formulation and (ii) at least one inorganic carbonate in an amount to achieve a weight ratio of the at least one inorganic carbonate to the powderous formulation of at least 1:1. The at least one inorganic carbonate is present in an amount such that a weight ratio (w/w) in the uniform mixture of the at least one inorganic carbonate to the compound of formula (1) is at least 50:1 sufficient to achieve storage stability of the uniform mixture such that retention of the compound of formula (I) is improved by at least 10% when stored in a closed container for 1 month at 25° C. and 50% relative humidity as compared to a mixture which does not include the at least one inorganic carbonate.

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