公开(公告)号：US12202853B2

公开(公告)日：2025-01-21

申请号：US18156750

申请日：2023-01-19

Applicant: DSM IP ASSETS B.V.

Inventor： Alexander Lucia Leonardus Duchateau ,  Peter Philip Lankhorst ,  Willebrordus Bernardus Van Scheppingen

IPC: C07H17/08

Abstract: The present invention is directed to a process for purifying natamycin, to an epoxide polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macrolide.

公开(公告)号：US11344051B2

公开(公告)日：2022-05-31

申请号：US15563475

申请日：2016-04-04

Applicant: DSM IP ASSETS B.V.

Inventor： Robertus Antonius Mijndert Van Der Hoeven ,  Peter Philip Lankhorst ,  Silvia Gosiewska

IPC: A23L27/30 ,  C12P19/56

Abstract: The present invention relates to a steviol glycoside having the formula of (I) wherein at least 3 sugar moieties are present at positions R1 and at least three sugar moieties are present at position R2 and wherein the steviol glycoside comprises at least seven sugar moieties all of which are linked, directly or indirectly, to the steviol aglycon by β-linkages.

公开(公告)号：US11540544B2

公开(公告)日：2023-01-03

申请号：US17727130

申请日：2022-04-22

Applicant: DSM IP ASSETS B.V.

Inventor： Robertus Antonius Mijndert Van Der Hoeven ,  Peter Philip Lankhorst ,  Silvia Gosiewska

IPC: A23L27/30 ,  C12P19/56

Abstract: The present invention relates to a steviol glycoside having the formula of (I) wherein at least 3 sugar moieties are present at positions R1 and at least three sugar moieties are present at position R2 and wherein the steviol glycoside comprises at least seven sugar moieties all of which are linked, directly or indirectly, to the steviol aglycon by β-linkages.

公开(公告)号：US11591360B2

公开(公告)日：2023-02-28

申请号：US17268252

申请日：2019-08-15

Applicant: DSM IP ASSETS B.V.

Inventor： Alexander Lucia Leonardus Duchateau ,  Peter Philip Lankhorst ,  Willebrordus Bernardus Van Scheppingen

IPC: C07H17/08

Abstract: The present invention is directed to a process for purifying natamycin, to an epoxide polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macrolide.

公开(公告)号：US10858683B2

公开(公告)日：2020-12-08

申请号：US16402779

申请日：2019-05-03

Applicant: DSM IP Assets B.V.

Inventor： Ellen Speetjens ,  Peter Philip Lankhorst

IPC: C12P19/02 ,  C12P19/04 ,  A61K31/716 ,  C12P19/14 ,  A23K20/163 ,  A23K50/75 ,  A23K50/30 ,  C08B37/00 ,  A61K36/064

Abstract: The present invention provides a process for the treatment of a composition comprising yeast cell walls comprising β-1,3-glucans which are insoluble when extracted with water and partially soluble when extracted with DMSO, the process comprising contacting said composition with laminaripentaose-producing-β-1,3-glucanase and inactivating the laminaripentaose-producing-β-1,3-glucanase to result in a composition comprising yeast cell walls wherein the β-1,3-glucans have an improved solubility in DMSO and the ratio of β-glucans soluble in DMSO compared to water is greater than or equal to 2.

公开(公告)号：US12275755B2

公开(公告)日：2025-04-15

申请号：US18164743

申请日：2023-02-06

Applicant: DSM IP ASSETS B.V.

Inventor： Alexander Lucia Leonardus Duchateau ,  Peter Philip Lankhorst ,  Willebrordus Bernardus Van Scheppingen

IPC: C07H17/08 ,  C07H1/06

Abstract: The present invention is directed to a process for purifying natamycin, to an all-trans polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macrolide.

公开(公告)号：US11623939B2

公开(公告)日：2023-04-11

申请号：US17267790

申请日：2019-08-15

Applicant: DSM IP ASSETS B.V.

Inventor： Alexander Lucia Leonardus Duchateau ,  Peter Philip Lankhorst ,  Willebrordus Bernardus Van Scheppingen

IPC: C07H17/08 ,  C07H1/06

Abstract: The present invention is directed to a process for purifying natamycin, to an all-trans polyene amphoteric macrolide, to a composition comprising said polyene amphoteric macrolide and to a process for preparing said polyene amphoteric macrolide.

公开(公告)号：US10392639B2

公开(公告)日：2019-08-27

申请号：US15127133

申请日：2015-03-20

Applicant: DSM IP Assets B.V.

Inventor： Ellen Speetjens ,  Peter Philip Lankhorst

IPC: C12P7/02 ,  C12P19/04 ,  A61K31/716 ,  C08B37/00 ,  C12P19/14 ,  A23K20/163 ,  A23K50/75 ,  A23K50/30 ,  A61K36/064

Abstract: The present invention provides a process for the treatment of a composition comprising yeast cell walls comprising β-1,3-glucans which are insoluble when extracted with water and partially soluble when extracted with DMSO, the process comprising contacting said composition with laminaripentaose-producing-β-1,3-glucanase and inactivating the laminaripentaose-producing-β-1,3-glucanase to result in a composition comprising yeast cell walls wherein the β-1,3-glucans have an improved solubility in DMSO and the ratio of β-glucans soluble in DMSO compared to water is greater than or equal to 2.

公开(公告)号：US20130309721A1

公开(公告)日：2013-11-21

申请号：US13949090

申请日：2013-07-23

Applicant: DSM IP ASSETS B.V.

Inventor： Peter Philip Lankhorst ,  Hendrik Louis Bijl ,  Ibrahim Oezkan

IPC: C12P21/00

CPC classification number: C12P21/005 ,  C07K14/39 ,  C12H1/14 ,  C12P21/06

Abstract: The present invention describes a mannoprotein solution which has a turbidity, when measured by nephelometry at a concentration of 200 g/l of mannoprotein and at a pH in the range of pH 4 to pH 8 lower than 70 NTU, preferably lower than 60 NTU, more preferably lower than 50 NTU, most preferably lower than 40 NTU. This solution can be advantageously used in the stabilisation of wine against tartrate salt precipitation because it is very clear and can be added directly to the wine without causing any turbidity.

Abstract translation: 本发明描述了当浓度为200g / l的甘露糖蛋白并且在pH 4至pH 8低于70NTU，优选低于60NTU的pH范围内通过比浊法测量时具有浊度的甘露糖蛋白溶液， 更优选低于50NTU，最优选低于40NTU。 这种溶液可以有利地用于使葡萄酒稳定，防止酒石酸盐沉淀，因为它是非常清楚的，并且可以直接加入葡萄酒中而不引起任何浑浊。